The UConn Huskies (24-3) will look to keep pace atop the Big East standings following a deflating home loss against Creighton on Wednesday. The Huskies are currently ranked fifth in the country and sit at 14-2 in conference play this season.
Meanwhile, the Villanova Wildcats (21-5) are riding a six-game winning streak and just beat Xavier 92-89 in overtime on Tuesday.
Let’s look at a UConn vs. Villanova prediction and picks for Saturday’s battle at Xfinity Mobile Arena in Philadelphia, tipping off at 5:30 p.m. ET on TNT. Use PrizePicks and PrizePicks Team Picks to make predictions on player picks, game winners, over/unders, spreads, and more.
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UConn vs. Villanova Prediction, Spread, Over/Under
The Huskies outlasted the Wildcats in the first matchup, 75-67, in overtime back on January 30 at UConn. Despite a back-and-forth affair throughout regulation, UConn was able to outscore Villanova 14-6 in the extra session to come away with a big win.
Villanova has lost seven of its last eight contests to UConn, with the most recent victory coming in January 2025.
UConn vs. Villanova Spread, Over/Under
The Huskies enter this matchup as 1.5-point favorites, returning a 1.61x payout on PrizePicks Team Picks if they win outright.
The Wildcats are narrow home underdogs with a 2.12x payout if they win, via PrizePicks Team Picks.
- Spread: UConn Huskies -1.5
- Over/Under: 140.5
- Game Winner Payout: UConn 1.61x | Villanova 2.12x
Team Picks data is live as of writing and is subject to change.
UConn vs. Villanova Prediction on Spread
Here are some stats to know to get you set for UConn vs. Villanova tonight, including insights on our UConn vs. Villanova prediction.
- The Huskies own a Big East-worst 9-18 against-the-spread record, producing just a 33.3% cover rate.
- The Wildcats have a 17-9 ATS record with a 6-2 ATS mark over their last eight.
- UConn and Villanova are very evenly matched on the offensive end. The Huskies average 79.4 PPG (fourth in the Big East), while the Wildcats rack up 78.3 PPG (fifth).
- The Huskies connected on 36.8% of their shots from beyond the arc, ranking second in the Big East. Meanwhile, the Wildcats rank third in that department, as they shoot 36.2% from deep.
- Villanova has averaged 81.3 PPG during its current six-game winning streak.
- The Wildcats are 7-3 ATS in their last 10 games vs. the Huskies but have won just two of those contests outright.
UConn vs. Villanova Picks for PrizePicks Today: 2/21/26
Here are three top UConn vs. Villanova picks to target on Saturday. Key PrizePicks player projections are headlined by UConn C Tarris Reed Jr., Villanova G Tyler Perkins, and UConn G Silas Demary Jr.
UConn C Tarris Reed Jr. vs. Villanova Projection: 20.5 Pts + Rebs
- The senior leads the Huskies in rebounds with 7.7 per contest.
- Reed has recorded at least 21 points and rebounds in three of his last five games.
- The former four-star recruit scored 15 points on 7-of-11 shooting and secured 12 rebounds in Wednesday’s loss to Creighton.
- In UConn’s win against Villanova on January 24, Reed netted 10 points on just 4-of-7 shooting while pulling down 11 rebounds.
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Villanova G Tyler Perkins vs. UConn Projection: 14.5 Points
- Perkins has averaged a career-best 13.7 PPG in his second season with Villanova after transferring from Penn following the 2023-24 campaign.
- The Wildcats' leading scorer has recorded at least 15 points in 10 consecutive games dating back to January 13 vs. Providence.
- Perkins scored 16 points on 6-of-16 shooting in a 75-67 overtime loss vs. UConn on Jan. 24.
- The Villanova G is shooting a career-high 36.0% from beyond the arc. Perkins has connected on 38.9% of his 3-point shots in his last three games.
UConn G Silas Demary Jr. vs. Villanova Projection: 12.5 Points
- The junior G has scored at least 13 points in six of his last seven games.
- Demary ranks second on the Huskies with a 45.2% shooting clip from deep. However, the former Georgia Bulldog has shot 50% (10-of-20) from 3-point land over his last six outings.
- The UConn junior scored just 10 points vs. Villanova on January 24 but missed seven of his 11 field goal attempts.
- Demary averages 11.5 PPG, ranking fifth on the Huskies.
Make #5 UConn vs. Villanova Picks on PrizePicks
Can UConn continue to be road warriors in the Big East, or will Villanova pull off the upset at home? You can get in on this weekend's college basketball action and make picks with PrizePicks.
Just pick at least two players and predict More or Less on their projected stats on PrizePicks, or make your picks on winners, spreads, and over/unders on Team Picks, now available in 34 states!
Check out the Playbook throughout the season for more CBB picks, predictions, and news every day.
