Both UCLA and UConn failed to cover the spread in their first-round victories on Friday. UConn is listed as a 4.5-point favorite for the second round against UCLA at 8:45 p.m. ET, televised on TNT.
The Huskies (30-5) just held off Furman, 82-71, despite going 5-of-25 from 3-point range. The Bruins (24-11) stymied a late UCF rally in a 75-71 victory while leading scorer F Tyler Bilodeau sat out with a knee injury.
Let’s look at a UCLA vs. UConn spread prediction for this showdown at Xfinity Mobile Arena. Make your college basketball picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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UCLA vs. UConn Prediction, Spread, Over/Under
This is the second meeting between these blue-blood schools. UCLA last outlasted UConn in the 1995 Round of 8, 102-96, on its way to a title.
The Huskies face their first Big Ten opponent in the NCAA Tournament since knocking off Purdue for the title in 2024.
The Bruins, meanwhile, seek their first Round of 16 appearance since 2023 while taking on their first Big East foe in the tourney since losing to Villanova in 2009.
UCLA vs. UConn Spread, Over/Under
The Huskies enter this matchup as 4.5-point favorites, returning a 1.49x payout on PrizePicks Team Picks if they win outright.
The Bruins are underdogs with a 2.5x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: UConn Huskies -4.5 (1.92x payout)
- Over/Under: 136.5 (1.85x payout on over)
- Game Winner Payout: UCLA 2.5x | UConn 1.49x
Team Picks data is live as of writing and is subject to change.
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UCLA vs. UConn Prediction on Spread – 3/22/26
Here are some key stats to know before locking in your UCLA vs. UConn prediction on spread for Sunday, March 22 on PrizePicks.
- UConn owns a dreadful 13-22 against-the-spread mark, capped off by a 4-8 ATS slump in the last 12 games.
- The non-cover against Furman snapped a 14-0 ATS run in the NCAA Tournament for UConn dating back to 2023.
- UCLA posted a 7-1 ATS hot stretch before Friday’s win over UCF. The Bruins led by 14 with 7 minutes remaining before the Knights cashed as 5.5-point underdogs.
- The Bruins are 2-2 without Bilodeau (17.6 PPG) in the lineup.
- UConn ranks 14th nationally in adjusted defensive efficiency, also sitting 13th in defensive 2-point percentage (45.9%).
- The Huskies have struggled from long range recently, converting on 16 of 69 3-point tries in the last three games.
- The Bruins lost seven of 10 times when shooting worse than 48% on effective field goal percentage. UConn is ninth, holding opponents to a 45.9 EFG%.
- Out of the last 14 NCAA Tournament victories for head coach Dan Hurley’s squad, 13 came by double digits. The smallest margin of victory in that stretch was eight in the first round against Oklahoma last season.
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Make UCLA vs. UConn Picks on PrizePicks
The Huskies seek a return to the Round of 16 for the first time since their last run to the National Championship Game in 2024. Can the Bruins shut down the Huskies on Sunday night?
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