Patriots RB TreVeyon Henderson produced an up-and-down rookie season in 2025. However, as he prepares for his second season, the injury bug may have already slowed down the electric running back out of Ohio State.
During Monday’s practice, Henderson reportedly suffered a lower ankle injury, according to Christopher Price of The Boston Globe. The injury occurred when Henderson slipped on the turf. At Tuesday's practice, Henderson was sidelined again.
When are the Patriots expecting Henderson to return from the ankle injury? Below, we’ll look for the latest injury news to answer that question with a full TreVeyon Henderson injury update, along with the impact on fantasy football and projections for the Patriots on PrizePicks.
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TreVeyon Henderson Injury Update: When Will Patriots RB Return From Ankle Injury?
Early indications suggest that Henderson's injury may be minor enough to get on the field for the NFL season opener in just over two weeks on Wednesday, Sept. 9, but it's not 100% as of now.
After Henderson slipped on the turf, the Patriots RB was seen “walking and moving fine" at practice, according to Price. That's a good sign that it's not a major injury; however, Henderson is getting some precautionary tests done on his right ankle.
Henderson wasn’t expected to play in New England’s preseason finale against the Cleveland Browns on Thursday. He likely wouldn’t return to the practice field until the days leading up to the Patriots’ Week 1 contest against the Seattle Seahawks, assuming the tests come back clean.
Henderson played in all 17 games as a rookie after being selected in the second round of the 2025 NFL Draft. The former Ohio State star led the Patriots in rushing yards (911), touchdowns (9), and carries (180) in his rookie campaign.
The speedy RB missed eight career games at Ohio State, but did play in all 16 games during his final collegiate season.
Could TreVeyon Henderson Injury Open the Door For Rhamondre Stevenson in Fantasy Football?
If the ankle injury turns out to be nagging and creates an issue into the regular season, Henderson’s absence would certainly be a hindrance to the Patriots’ offense.
Henderson wasn’t a bell cow RB as a rookie by any means, but he made the most of his opportunities and grew into a bigger role as the year continued. According to PlayerProfiler, Henderson’s 911 yards ranked 21st among qualifying running backs and averaged 53.6 rushing yards per contest.
Henderson had only a 46.2% snap share in 2025, ranking 42nd among NFL running backs.
The Patriots split reps between Henderson and veteran RB Rhamondre Stevenson throughout the 2025 season, and they are again expected to share the backfield in 2025. Being in the backfield of an offense that tends to lean on QB Drake Maye, with a +2.4% pass rate over expectation (fourth highest in NFL), often leads to underwhelming fantasy results on a week-to-week basis.
Even with the minor injury, Henderson is currently projected for 699.5 rush yards and 5.5 rushing TDs for the 2026 season on PrizePicks NFLSZN game. Rhamondre Stevenson is projected similarly, with 624.5 season rushing yards and 6 rush TDs.
Henderson topped the 100-yard mark in two contests, including rushing for a season-high 148 yards and 2 TDs against the Buffalo Bills on Dec. 14.
As a receiver, Henderson registered an 8.8% target share, ranking 24th among qualifying RBs. He also racked up 6.3 yards per reception.
If Henderson ends up missing time to start the regular season, the Patriots would lean on Stevenson as the team’s bell-cow RB. That may also likely affect New England’s season-long projections, including the Patriots carrying a 1.58x payout to reach 10+ wins, via PrizePicks Team Picks.
Stevenson may not have been quite as dangerous as Henderson, but still received a considerable amount of work last season. The veteran RB averaged 4.6 yards per carry and totaled 603 rushing yards and 7 TDs in 14 games in 2025.
The Patriots did run 28.9 rushing plays per game in 2025 (seventh), so regardless of which RB is on the field, they will likely receive a large amount of work, potentially enough to be considered weekly flex options in traditional fantasy.
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Second-year RB TreVeyon Henderson suffered a lower ankle injury during Monday’s practice, causing him to miss practice on Tuesday.
However, reports suggest the injury could be relatively minor and may not affect his regular-season availability. Still, Henderson’s status is certainly worth paying attention to ahead of the Patriots’ Week 1 matchup against the Seattle Seahawks on Sept. 9.
The NFL regular season begins on September 9 as Henderson and the Patriots take the field, and users can make NFL predictions for the upcoming campaign, such as the Super Bowl winner, divisional winners, and win totals, on PrizePicks Team Picks — available in 36 states!
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