Thunder vs. Bucks Prediction, Spread: Giannis, Holmgren Throw Down

Bucks F Giannis Antetolounmpo and Thunder C Chet Holmgren battle for the basketball in an NBA game.
AP Photo/Morry Gash

The Oklahoma City Thunder (36-8) wrap up a four-game road trip when they take on the Milwaukee Bucks (18-24) at Fiserv Forum on Wednesday evening. The game tips at 9:30 p.m. ET and can be seen on ESPN.

Below, are our Thunder vs. Bucks prediction and spread for Wednesday’s matchup. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spread, and total.

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Thunder vs. Bucks Prediction, Spread, Over/Under

The Thunder haven’t missed a beat after winning the 2024-25 NBA title — G Shai Gilgeous-Alexander and his crew have yet to record double-digit losses and has won six of its last seven.

Meanwhile, the Bucks have struggled this season and find themselves outside the playoffs, sitting 11thin the Eastern Conference. Milwaukee is coming off a 112-110 win vs. the Atlanta Hawks on MLK Day, but had dropped three straight prior to that.


Thunder vs. Bucks Over/Under, Spread

The Thunder enter Wednesday’s game as 9.5-point road favorites, returning a 1.21x payout on PrizePicks Team Picks if they win outright.

The Bucks are home underdogs with a 3.84x payout if they win, via PrizePicks Team Picks.

  • Spread: Oklahoma City Thunder -9.5
  • Over/Under: 226.5
  • Game Winner Payout: Thunder 1.21x | Bucks 3.84x

Team Picks data is live at the time of writing and is subject to change.


Thunder vs. Bucks Injury Report

Let’s dive into the full Thunder vs. Bucks injury report for Wednesday, via NBA.com.

Thunder Injury Report

  • C Isaiah Hartenstein (calf): OUT
  • G Jalen Williams (hamstring): OUT
  • G Alex Caruso (groin): OUT

Bucks Injury Report

  • G Kevin Porter Jr. (oblique): Questionable
  • C Myles Turner (ankle): Questionable

Thunder vs. Bucks Prediction on Spread

Here are some stats to know to help you make your Thunder vs. Bucks prediction on Wednesday, January 21.

  • Oklahoma City is just 10-11 against the spread as a road favorite this season, ranking 11th in the NBA.
  • Milwaukee has a 4-5 record against the spread as home underdog.
  • The Thunder rank second in per-game scoring (121.4), while the Bucks are't nearly as dangerous, ranking 27th with 112.4 points per contest.
  • The Bucks knock down 39.4% of their shots from three, ranking second behind only the Nuggets.
  • Meanwhile, Oklahoma City allows its opponents to shoot 37.2% from beyond the arc, the sixth-highest clip in the league.
  • The Thunder give up the fewest fast-break points per contest (11.4), while the Bucks surrender 15.0 fast-break points (15th).
  • Oklahoma City is 3-1 against the spread in its last four meetings vs. Milwaukee, winning all three contests outright.

Thunder vs. Bucks Picks for PrizePicks Today: Wednesday, January 21

Here are the top Thunder vs. Bucks picks to target for Wednesday, January 21, on PrizePicks. Player stat projections via PrizePicks are headlined by Bucks F Giannis Antetokounmpo and Thunder C Chet Holmgren.

Bucks F Giannis Antetokounmpo vs. Thunder Projection: 39.5 Pts+Rebs

  • Antetokounmpo averaged 32.6 points and rebounds over his last five games. During the month of January, the Bucks star posted 36.9 combined points and rebounds.
  • According to NBA.com, Antetokounmpo tallied a 35.6% usage rate, ranking third in the entire NBA. Only Jaylen Brown (36.8%) and Luka Doncic (36.2%) have higher usage rates in the league.
  • The Greek Freak spends 32.4% of his time on the floor on ball, per databallr.
  • The former MVP pulled down double-digit rebounds in just one of his last five games.

Thunder C Chet Holmgren vs. Bucks Projection: 28.5 PRA

  • Holmgren averaged 27.8 points, rebounds, and assists in his last five contests.
  • According to Add More Funds, Holmgren has racked up 29.4 points per 100 possessions.
  • The former Gonzaga standout secured 41.9% of his contested rebound opportunities this season, per NBA.com.
  • Holmgren tallied at least 10 rebounds in four of his last six games.

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Make Thunder vs. Bucks NBA Picks on PrizePicks

Thunder vs. Bucks picks are one of several avenues in which basketball fans can get in on the NBA action on Wednesday.

You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.

Stick around with the Playbook for continued NBA predictions, picks, and news.


Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service, see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

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about the author

Chris Bengel is a veteran sports writer with two decades of experience covering the NBA, NHL, and NFL for CBS Sports and 247Sports. He attended Rowan University where he earned a degree in journalism and is a tortured Philadelphia sports fan residing in Harrisburg, PA.

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