Texans vs. Chargers Prediction, Picks for NFL Saturday Game: C.J. Stroud Heater?

Texans QB C.J. Stroud throws a football in an NFL game.
AP Photo/Tony Gutierrez

The Texans and Chargers, two teams in the heat of the AFC playoff race, meet in the first of two Saturday NFL games.

Trailing the Jaguars by one game in the AFC South, Houston rolls into the game riding a seven-game win streak — currently the longest in the league — while the Chargers have taken four straight and are one game back of the Denver Broncos in the AFC West.

The game kicks off at 4:30 p.m. ET on NFL Network. 

Below, we'll break down our Texans and Chargers prediction and Saturday game picks for Week 17, including the top player picks on PrizePicks real money NFL game, including Texans QB C.J. Stroud and WR Nico Collins, and Chargers QB Justin Herbert. 

{{nfl_offer_banner="/style-system/ui-components-playbook"}}

Texans vs. Chargers Over/Under Picks, Spread, Over/Under 

The Texans and Chargers meet for the first time since Houston's 32-12 win in the AFC Wild Card round last January. Overall, the Chargers lead the series 6-4, but Houston has won four of the last six games. 

Texans vs. Chargers Over/Under, Spread

The Chargers enter the Week 17 rumble as 2.5-point favorites, returning a 1.75x payout on PrizePicks Team Picks if they win.

The Texans are big underdogs with a 2x payout if they win, via PrizePicks Team Picks.

  • Spread: Los Angeles Chargers -2.5
  • Total: 39.5
  • Game Winner Payout: Chargers 1.75x | Texans 2x

Texans vs. Chargers Prediction on Over/Under

The listed total of 39.5 is the third-lowest total of Week 17, only ahead of Christmas nght’s Broncos-Chiefs tilt (36.5) and Sunday’s Steelers-Browns matchup (35.5) 

  • The Texans have played 10 of their 15 games to the under this season, which includes hitting the over in the last two games. 
  • The 10 unders for Houston are third-most this season, one less than Kansas City and New Orleans, both with 11. 
  • The 39.5 listed over/under marks the fourth game this season under 40 for the Texans. Houston is 2-1 to the over in the three previous outings, including going over last week’s 39.5.
  • The main reason for Houston’s 10 unders has been its defense, which has allowed the fewest points at points per game at 16.6.
  • The Texans also lead the NFL in total defense (272.3 yards per game) and pass yards per play (5.61).
  • DVOA has the Texans as the second-best rated defense, behind the Seahawks. 
  • On the offensive side of the ball, they sit at 18th with 23.1 points per game. 
  • The Chargers have played nine of their 15 games to the under this season, just one less under than the Texans. 
  • The last three, and five of the last six Chargers games have gone below the listed over/under.
  • Saturday’s game marks the first over/under of the season below 40 for the Chargers. By comparison, last week’s over/under was listed at 51.5 (totaled 51). 
  • Los Angeles’ defense is eighth in the NFL, allowing 20.1 PPG, and third in total defense, allowing 283.1 yards per game.
  • On the offensive side, the Chargers are also in the middle of the pack at 16th, averaging 23.3 points per game.

Texans vs. Chargers Picks for PrizePicks

Here are three Texans vs. Chargers player picks for Saturday's game for PrizePicks real money NFL game, including Texans QB C.J. Stroud and WR Nico Collins and Chargers QB Justin Herbert.

Pick More or Less on these projections on PrizePicks — plus thousands more — to win real money this NFL season.  

Texans QB C.J. Stroud Projection vs. Chargers: 223.5 Pass Yards

  • Texans QB C.J. Stroud has reached his projected passing yards in six of 12 games. 
  • The former Buckeye has had the same listed projection of 223.5 passing yards each of the past three weeks, recording more once and less once. For all 12 games, Stroud’s passing projection has been between 200.5 and 234.5.  
  • Since returning from injury in Week 13, Stroud has thrown 5 TD passes with 1 INT, averaging 231.5 passing yards per game.
  • The Texans’ QB ranks 15th of 27 QBs with a 93.6 passer rating. 

Texans WR Nico Collins Projection vs. Chargers: 64.5 Receiving Yards

  • Texans WR Nico Collins has hit more than his projected receiving yards in eight of 14 games. 
  • The listed projected receiving mark of 64.5 yards is the lowest projection since Week 10.  
  • Collins has recorded 65+ yards in six of the last eight games. 
  • The Michigan product averages 15.6 yards per catch, fourth-best in the NFL. 

Chargers QB Justin Herbert Projection vs. Texans: 216.5 Pass Yards

  • Chargers QB Justin Herbert failed to reach his passing projection in eight of 15 games this season, but has recorded more in each of the last two weeks. 
  • Herbert’s projected passing mark of 216.5 yards is the second-lowest of the season, only ahead of Week 15’s 208.5 (threw for 210).  
  • The former Oregon standout passed for 300 yards last week vs. Dallas, his first game over 250 yards since his Oct. 19 outing against Indy. 
  • The Chargers QB has 25 passing TDs on the season, tied for fifth-most in the NFL. 
{{nfl_offer_banner="/style-system/ui-components-playbook"}}

Make Texans vs. Chargers Predictions on PrizePicks

Can the Texans stretch their winning streak to eight games and clinch a playoff spot? Or will the Chargers inch closer to the Broncos in the AFC West race? 

As the NFL season enters its 17th week, there's no better place to get real money action with your NFL predictions than on PrizePicks.

There is a wide variety of player stat projections on the NFL board, so you can make predictions on whatever you'd like — from yards to field goals. Just pick your players, predict More or Less on their stats, and cash in on your predictions if you're right.

It's the simplest way to get real-money action on NFL action. 

Stay locked in on Playbook all the way through the Super Bowl for NFL predictions, picks, and news.


Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

David Bearman spent 18 years with ESPN in their Stats & Information Department and overseeing their betting content. From 2023-25, he served as Chief Content Officer of Pro Football Network, overseeing all content, including coverage of Super Bowls 58 and 59. He is also the Founder of Betting with Bearman, a 3x a week betting newsletter and weekly podcast on Bleav Podcast Network.

New User Offer
Get $50 Instantly

In Lineups after you play $5

Play Now
PrizePicks Logomark

Smart Picks Start Here.

Get expert insights, analysis, and news delivered straight to your inbox.

Green checkmark emoji
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
official Partner of

Join the largest squad in Daily Fantasy Sports

Join our Discord
let’s goooo