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St. John’s vs. UConn Prediction, Spread, NCAAB Picks for February 25

St. John’s F Zuby Ejiofor lays in a basketball in an NCAAB game
AP Photo/Aaron Gash

The top spot in the Big East is on the line in the Constitution State on Wednesday.

The St. John’s Red Storm (22-5) sit in first place of the conference at 15-1, coming off an 81-52 rout of Creighton on Saturday.

The UConn Huskies (25-3) rebounded from their second Big East defeat to knock off Villanova, 73-63 to improve to 15-2 in the league. 

Let’s look at the St. John’s vs. UConn spread, prediction, and NCAAB picks for Wednesday’s showdown at PeoplesBank Arena in Hartford, tipping off at 7:00 p.m. ET on Peacock.

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St. John’s vs. UConn Prediction, Spread, NCAAB Picks for February 25

The Johnnies held off the Huskies at Madison Square Garden, 81-72 as 1.5-point underdogs on February 6. That loss not only snapped UConn’s 18-game winning streak, but head coach Dan Hurley’s squad was handed their first Big East loss.

The Red Storm outscored the Huskies, 22-5 at the foul line, but St. John’s shot 5-of-19 from long distance.

St. John’s lost the first three matchups against UConn after Rick Pitino took over as head coach in 2023. However, the Red Storm are 3-0 in the past three meetings with the Huskies.

St. John’s vs. UConn Over/Under, Spread

The Huskies enter this matchup as 5.5-point favorites, returning a 1.36x payout on PrizePicks Team Picks if they win outright.

The Red Storm are road underdogs with a 2.77x payout if they win, via PrizePicks Team Picks.

  • Spread: UConn -5.5
  • Over/Under: 147.5
  • Game Winner Payout: St. John’s 2.77x | UConn 1.36x

(Team Picks data is live as of writing and is subject to change)


St. John’s vs. UConn Numbers to Know

Here are some facts and figures to get you set for St. John’s vs. UConn tonight, including insights on our St. John’s vs. UConn prediction.

  • Since Pitino took over at St. John’s, the Red Storm covered the spread in five of six matchups, including four as an underdog.
  • UConn failed to cover in four consecutive games before knocking off Villanova as 3.5-point road favorites on Saturday.
  • The Huskies lost outright as 15.5-point favorites in their last home game, getting tripped up by Creighton, 91-84 on February 18.
  • Since starting Big East play 3-0 against the spread (ATS), UConn struggled to a 3-11 ATS mark the last 14 games.
  • Tonight marks the third time the Johnnies are underdogs this season. St. John’s lost to Pitino’s old team Kentucky (78-66) on December 20 before the victory over UConn earlier this month.
  • UConn ranks first in Big East play in offensive efficiency, effective field goal percentage (56.4%), 2-point shooting (56.1%), and 3-point shooting (37.9%).
  • St. John’s is the top team in defensive efficiency in conference action and the best in defending the 2-point shot (46.1%). 
  • In the first matchup, St. John’s allowed the highest EFG% to any team in league play as UConn shot 63.2% in the loss.
  • In the past six games, the Red Storm converted 31-of-112 attempts from 3-point range, a 27.6% clip.

St. John’s vs. UConn CBB Player Picks

Here are three top St. John’s vs. UConn picks to target on Wednesday. Key PrizePicks player projections are headlined by three players: St. John’s F Zuby Ejiofor, UConn C Tarris Reed, Jr., and Red Storm F-G Bryce Hopkins.

St. John’s F Zuby Ejiofor vs. UConn Projection: 16 Points

  • Ejiofor posted 21 points on 6-of-10 shooting in the victory over UConn at the Garden.
  • In the last three games, the senior has failed to score more than 15 points.
  • In seven road conference outings, Ejiofor averages 14.2 points per game (PPG). He has scored more than 16 points twice at Butler (18) and Villanova (17).
  • The Texas native scored at least 30% of the team’s points once in the last 14 games, coming against the Huskies. 

UConn C Tarris Reed, Jr. vs. St. John’s Projection: 21.5 Pts+Rebs

  • Reed averages double-figures for the first time in his career, putting up 13.6 PPG.
  • In the loss to St. John’s, the senior scored 12 points and pulled down 6 rebounds. 
  • Reed shot 12-of-16 from the floor in the last two games against Creighton and Villanova.
  • The St. Louis native averages 7.7 rebounds per game in the past 11 contests, including four double-digit rebounding performances.

St. John’s F-G Bryce Hopkins vs. UConn Projection: 13.5 Points

  • The former Providence standout compiled 15 points in Saturday’s rout of Creighton.
  • In five of the past six games, Hopkins posted at least 14 points. He scored 14 in the win over UConn, including hitting 5 free throws.
  • Hopkins averaged 17.0 PPG in his last five road outings, capped off by a 23-point showing at Marquette last Wednesday. 
  • The senior isn’t much of a threat from long distance, hitting 29% this season and a single 3-pointer in the past four games.

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Make St. John’s vs. UConn CBB Picks on PrizePicks

The winner of tonight’s showdown will likely grab the top seed in the Big East tournament next month. UConn looks for revenge while St. John’s goes for the season sweep on the road.

There’s never been a better time to add to the excitement of every CBB moment than with PrizePicks.

There are hundreds of player stat projections on the CBB board for every game; just pick at least two player stat projections to build your Lineup on PrizePicks. Or, make your picks on winners, spreads, and over/unders on Team Picks, now available in 34 states!

Check out the Playbook throughout the season for more CBB picks, predictions, and news every day.

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Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Kevin has spent the last 15 years in the sports gambling space. He covered all major sports at VegasInsider both as a writer and handicapper from 2009 until 2024. He has also covered college basketball and MLB for the Action Network.

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