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Spurs vs. Trail Blazers Prediction, NBA Playoff Picks, Spread – 4/24/26

Trail Blazers SF Deni Avdija dribbles the ball vs. the Kings.
AP Photo/Justine Willard

The San Antonio Spurs vs. Portland Trail Blazers game is set to tip off at 10:30 p.m. ET on Friday, April 24, with the Spurs entering as 1.5-point favorites on the spread, via PrizePicks.

The Spurs lost C Victor Wembanyama to a concussion in Game 2, and the Trail Blazers came away with a narrow win. As the series shifts to Portland, will the Spurs bounce back with their center listed as questionable? 

Below, we'll break down our Spurs vs. Trail Blazers prediction and picks for Friday’s NBA game, including the spread, over/under, and key player picks for PrizePicks.

Don’t wait until tip-off — make your Spurs vs. Trail Blazers picks on PrizePicks now for tonight’s NBA game.

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Spurs vs. Trail Blazers Prediction, Spread, Over/Under – Friday, April 24

The Spurs were dealt a brutal blow in Game 2 when star C Victor Wembanyama suffered a concussion in the second quarter. Wembanyama banged his head off the court in a scary fall and was ruled out for the remainder of the game.

Wembanyama is currently in concussion protocol and is listed as questionable for Game 3 as a result, per the NBA injury report.

With Wembanyama out, the Trail Blazers were able to secure a narrow 106-103 win against the Spurs in Game 2. Portland G Scoot Henderson scored a game-high 31 points on 11-of-17 shooting, including knocking down 5 3-pointers.

The Trail Blazers held the Spurs to 29.2% (7-of-24) shooting from beyond the arc. San Antonio G Stephon Castle chipped in a team-high 18 points on 7-of-20 shooting, but no Spurs player converted double-digit shot attempts in Game 2. 


Spurs vs. Trail Blazers Spread, Over/Under – Friday, April 24

The Spurs enter Friday’s game as 1.5-point road favorites against the Trail Blazers, returning a 1.58x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Spurs vs. Trail Blazers game on PrizePicks.

  • Spread: San Antonio Spurs -1.5 (1.75x payout)
  • Over/Under: 220.5 (1.96x payout on Over)
  • Game Winner Payout: Spurs 1.58x | Trail Blazers 2.17x

Play the Spurs vs. Trail Blazers spread or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

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San Antonio Spurs vs. Portland Trail Blazers Timeline

Here is the full Spurs vs. Trail Blazers timeline, including the playoff series game-by-game and recent matchup history.

All-Time: Spurs, 115-101

Regular Season: Spurs, 2-1

Series: 1-1

Spurs vs. Trail Blazers Timeline, Schedule for 2026 NBA Playoffs

  • Game 1: Spurs 111, Trail Blazers 98
  • Game 2: Trail Blazers 106, Spurs 103
  • Game 3: Friday, April 24, 10:30 p.m. ET in Portland
  • Game 4: Sunday, April 26, 3:30 p.m. ET in Portland
  • Game 5: Tuesday, April 28, 9:30 p.m. ET in San Antonio
  • Games 6-7 are if necessary

Spurs vs. Trail Blazers Prediction on Spread for NBA Playoffs First Round

Here are the key game stats and trends behind our Spurs vs. Trail Blazers prediction on the spread for Friday, April 24.

Lock in your Spurs vs. Trail Blazers prediction on PrizePicks before the line moves.

  • The Spurs are 6-4 against the spread in their last 10 meetings vs. the Trail Blazers.
  • San Antonio has a 13-12-1 ATS record as a road favorite this season, producing a 52.0% cover rate.
  • According to NBA Advanced Stats, the Spurs own the fifth-best defensive rating (105.2) among playoff teams.
  • The Spurs are shooting 38.9% on 3-pointers, which ranks fourth among playoff teams. Meanwhile, the Trail Blazers are connecting on just 30.9% of their shots from beyond the arc (13th).
  • San Antonio has averaged 16.4 fast break points per contest this season, ranking 10th in the NBA.

Spurs vs. Trail Blazers Player Picks, Stats for PrizePicks – 4/24/26

Here are the top Spurs vs. Trail Blazers picks to target in the NBA Playoffs on PrizePicks for Friday, April 24. Today’s NBA picks for PrizePicks include SF Deni Avdija and C Luke Kornet.

Get a Payout Boost every night of the NBA Playoffs on PrizePicks.

Trail Blazers SF Deni Avdija vs. Spurs Projection: 23.5 Points

  • Avdija averaged 27.8 PPG over five games vs. the Spurs this season.
  • The Trail Blazers F has registered at least 24 points in eight of his last 10 games dating back to the regular season.
  • Avdija is shooting 50.0% (12-of-24) on triples in five games against the Spurs this season.
  • According to databallr, Avdija spends 35.2% of his time on the court on the ball, ranking in the 99th percentile.

Add Deni Avdija to your PrizePicks Lineup now.


Spurs C Luke Kornet vs. Trail Blazers Projection: 16.5 Pts + Rebs

  • Kornet totaled 14.0 combined points and rebounds per game in 16 contests without Victor Wembanyama this season.
  • The Spurs C tallied 10 points and 9 rebounds in 28 minutes with Wembanyama missing the majority of Game 2.
  • Kornet has posted 17.5 combined points and rebounds per game in the first-round series against Portland.
  • According to NBA Advanced Stats, Kornet has pulled down 40.0% of his contested rebound opportunities this postseason.

Add Luke Kornet to your PrizePicks Lineup now.

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NBA Playoffs Live Picks: Spurs vs. Trail Blazers on PrizePicks for Game 3

Here are some in-game angles to target for your Spurs vs. Trail Blazers live picks in tonight’s game. 

Every live NBA Lineup on PrizePicks during the NBA Playoffs enters you to win a trip to the NBA Finals — paid by PrizePicks. Make your live NBA Playoffs picks on PrizePicks.

  • The Spurs average 31.8 PPG in the first quarter this season, which ranks first in the NBA.
  • The Trail Blazers average just 55.2 PPG in the second half, sitting 25th in the league.
  • Spurs G Stephon Castle shoots better from the perimeter on the road this season, as he knocks down 34.4% of his 3-point shots in road games, compared to just 31.9% shooting at home.
  • Portland and San Antonio both have a pace of 96.50 during the NBA playoffs so far, which ranks ninth among postseason squads.

Make Spurs vs. Trail Blazers NBA Playoffs Picks on PrizePicks

Despite potentially lacking C Victor Wembanyama, the Spurs have the talent to secure a bounce-back road victory in Game 3. Will San Antonio be able to rise to the occasion in the face of adversity?

Don’t wait until tip-off — make your Spurs vs. Trail Blazers picks on PrizePicks now and earn real money if you’re right.

Pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily NBA predictions, picks, and news every day all the way through the 2026 NBA Finals.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Chris Bengel is a veteran sports writer with two decades of experience covering the NBA, NHL, and NFL for CBS Sports and 247Sports. He attended Rowan University where he earned a degree in journalism and is a tortured Philadelphia sports fan residing in Harrisburg, PA.

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