The Seattle Seahawks (12-3) are on an inside track to capture the top seed in the NFC playoffs and a first-round bye. Now, they travel to Charlotte to face the Carolina Panthers (8-7), who have overcome a 1-3 start to sit in the driver’s seat for the NFC South title.
Carolina knocked off Tampa Bay 23-20 last Sunday to jump the Buccaneers for first place, but the teams are set to meet again in Week 18.
With that in mind, let's take a look at a Seahawks vs. Panthers prediction and picks for Sunday’s showdown at Bank of America Stadium, kicking off at 1:00 p.m. ET on CBS. Use PrizePicks NFL to make picks on Week 17 and beyond.
Seahawks vs. Panthers Prediction, Spread, Over/Under
Seattle is riding a five-game winning streak, but failed to cover the spread in the last two victories over the Rams and Colts. The Panthers have alternated wins and losses in the past nine games.
Seahawks vs. Panthers Over/Under, Spread
The Seahawks enter this matchup as 6.5-point favorites, returning a 1.26x payout on PrizePicks Team Picks if they win outright.
The Panthers are home underdogs with a 3.44x payout if they win, via PrizePicks Team Picks.
- Spread: Seattle Seahawks -6.5
- Over/Under: 42.5
- Game Winner Payout: Seahawks 1.26x | Panthers 3.44x
Team Picks data is live as of writing and is subject to change.
Seahawks vs. Panthers Prediction on Spread
Here are some stats to know to get you set for Week 17, including insights on our Seahawks vs. Panthers prediction.
- The Seahawks erased a 16-point fourth-quarter deficit in last Thursday’s 38-37 overtime triumph over the Rams. The two matchups between the Seahawks and Rams were decided by a total of three points, but Seattle owns a one-game division lead over Los Angeles.
- Road is where the heart is for Seattle, who is 6-1 away from Lumen Field and has won 12 of the past 13 games outside the Pacific Northwest.
- The Seahawks are a perfect 5-0 as a road favorite and have covered the spread four times. The lone non-cover came in a 30-24 triumph at Tennessee in Week 12 as 13-point favorites.
- Carolina is seeking back-to-back wins for the first time since Weeks 6 and 7. The Panthers are averaging 11.0 points per game in their past five games off a victory.
- In six opportunities as a home underdog, the Panthers have covered five times, including the Week 13 upset of the Rams, 31-28.
- Seattle is traveling to Charlotte for the first time since 2019, as the Seahawks held off the Panthers, 30-24.
Seahawks vs. Panthers Picks for Week 17
Here are three top Seahawks vs. Panthers picks to target on Sunday. Key PrizePicks player projections are headlined by three players: Seattle QB Sam Darnold, Carolina QB Bryce Young, and Seahawks WR Jaxon Smith-Njigba.
Seahawks QB Sam Darnold vs. Panthers Projection: 228.5 Passing Yards
- Darnold may not match his career-high output of 4,319 passing yards from last season in Minnesota. He sits at 3,703 yards with two games remaining, although it’s the second-most yards in his eight-year career.
- The former USC standout has topped the 240-yard passing mark in five of the last six games. He has not thrown for fewer than 230 yards in seven road contests.
- The third pick of the 2018 draft ranks seventh at Pro Football Focus in passing grade among QBs making at least five starts (81.0). During his career-best season with the Vikings, he posted a 77.5 passing grade.
- In four of the last six home games, the Panthers have yielded at least 230 passing yards.
Panthers QB Bryce Young vs. Seahawks Projection: 198.5 Passing Yards
- Young has never thrown for 3,000 yards in a season. The third-year signal-caller currently sits at 2,691 yards while averaging 192.2 yards per game.
- The 2022 Heisman Trophy winner torched the Falcons for a career-high 448 yards in a Week 11 overtime victory. In the last four games, he has been held to fewer than 200 yards three times.
- In four of 13 games, the former Alabama star passed this projection. The Seahawks have yielded fewer than 200 passing yards in three of the past four road games.
- Young has failed to post consecutive 100+ passer ratings in 2025, coming off a 102.5 rating against Tampa Bay.
Seahawks WR Jaxon Smith-Njigba vs. Panthers Projection: 91.5 Receiving Yards
- JSN remains atop the receiving leaderboard with 1,637 yards, 45 yards ahead of Rams WR Puka Nacua heading into the final two games.
- The former Ohio State star racked up his 13th performance of at least 90 receiving yards in the Week 16 thriller against the Rams with 96 yards on 8 catches.
- Smith-Njigba has been the model of consistency in his third season. JSN has hauled in 52 receptions and 5 TDs each at home and on the road.
- Five of his nine 100+ yard receiving games are away from Lumen Field. The last player to amass 100 receiving yards at Carolina was Saints WR Chris Olave in Week 10.
Make Seahawks vs. Panthers Picks on PrizePicks
The Panthers can put themselves in a great position to win the NFC South with a victory over the red-hot Seahawks on Sunday.
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