The college football regular season is nearly finished, with two weeks until the conference championships. With the College Football Playoff rankings out, every team knows its chances of competing for a National Championship, which could make the upcoming weeks exciting.
There are just two top-25 matchups this week, but they could shape the CFB Playoff picture. No. 7 Oregon is currently in the bracket, but it may not be able to afford another loss. No. 15 USC could spoil that and, in the process, make a case for itself to be in the final 12.
Elsewhere, No. 8 Oklahoma’s win over Alabama last week has put them in the conversation, and a win over No. 22 Missouri could help their cause.
Below, we'll dig into Saturday CFB picks for Week 13 in our cheat sheet and list the projections for the top players in college football. PrizePicks is the simplest way to win real money with your CFB picks. Just pick your players, predict More or Less on their projected stats, and cash in if your picks are correct.
Week 13 Saturday CFB DFS Picks for PrizePicks
Here are the top CFB DFS picks for Week 13. Use this analysis to make your PrizePicks DFS picks for Saturday's games.
Miami QB Carson Beck Projection: 250.5 Passing Yards
No. 13 Miami vs. Virginia Tech Pick – 12 p.m. ET
Carson Beck has a higher passer rating than:
— M🎙ke McCoy (@UM_radio_Mic) November 20, 2025
Marcel Reed
Gunner Stockton
Ty Simpson
Arch Manning
He's also tied for 10th in the country with 18 TD passes and 3rd in the country in completion %. #BeatVT
- Carson Beck has more than 250 passing yards in three of his last five games.
- Virginia Tech is 74th in passing yards allowed per game (226.4).
- Beck is one of the more accurate passers in college football, ranking third in the FBS in completion percentage (73.2%).
- The Hokies rank fourth in the ACC in completion percentage against conference opponents (53.8%).
- Miami pass catchers are averaging 5.1 yards after the catch, the third-highest mark in the country.
- VT allows 4.1 yards after the catch, which ranks 115th.
Texas QB Arch Manning Projection: 291.5 Pass + Rush Yards
No. 17 Texas vs. Arkansas Pick – 3:30 p.m. ET
Arch Manning Is Elite pic.twitter.com/yL8ViUhAWB
— Matt Galatzan (@MattGalatzan) November 20, 2025
- Arch Manning has more than 330 combined passing and rushing yards in two of his last three games.
- Arkansas is 15th in the SEC in passing yards allowed per game to conference opponents (289.0) and 13th in rushing yards (191.0).
- Manning excels as a mobile QB and has the ninth-best scrambling EPA (0.777).
- The Razorbacks struggle against QBs who can move outside the pocket, ranking last (136th) in scrambling EPA (0.903).
- Arkansas has ranked in the bottom 40% for EPA per dropback in three of five games against SEC opponents, per CFB Graphs.
Penn State RB Kaytron Allen Projection: 91.5 Rushing Yards
Penn State vs. Nebraska Pick – 7:30 p.m. ET
Watching film on Kaytron Allen, and man, he’s just steady! His career has been so consistent. I have him graded higher than his teammate Singleton.
— Full-Time Dame 💰 (@DP_NFL) November 18, 2025
Allen has the look of a solid starting RB!pic.twitter.com/gItikrZv60
- Kaytron Allen is 17th in the nation with 917 rushing yards and has more than 140 rushing yards in two of his last four games.
- The senior just had a career-high 181 rushing yards against Michigan State, who ranks 13th in the Big Ten for rushing yards allowed per game (153.9).
- Nebraska ranks 14th in rushing yards yielded per game in the Big Ten (161.1).
- The former four-star recruit is 17th in the nation in yards after contact (601).
- The Cornhuskers are allowing 3.2 yards after contact per attempt (103rd).
Ohio State RB Bo Jackson Projection: 89.5 Rushing Yards
Rutgers vs. No. 1 Ohio State Pick – 12 p.m. ET
Ohio State true freshman RB Bo Jackson is tied for 7th in the country in rush yards per carry.
— The Buckeye Nut (@TheBuckeyeNut) November 18, 2025
He is the only true freshman in the Top 10 pic.twitter.com/nEBUzGHo11
- Bo Jackson has more than 100 yards in two of his last three games
- His last 100+ yard performance was in Week 12 against UCLA, which is second-to-last in the Big Ten in opponents’ rush EPA (0.050). Now he faces Rutgers, which is dead last.
- From Weeks 9-12, Jackson’s 7.0 yards per carry ranked seventh in the nation.
- The Scarlet Knights rank last in the FBS in yards allowed per carry (6.8).
- The true freshman’s 4.7 yards after contact from Weeks 9-12 was sixth in the FBS. Rutgers' defense is 123rd there.
Georgia Tech WR Eric Rivers Projection: 54.5 Receiving Yards
Pitt vs. No. 16 Georgia Tech Pick – 7 p.m. ET
Georgia Tech's Eric Rivers has CRAZY speed!
— IanM (@IannmNFL) November 15, 2025
Eric Rivers hasn't had a ton of production this season, but there are plenty examples of him OUT RUNNING defenses, getting overtop, uncontested. NFL teams might be attracted to such an athlete. pic.twitter.com/6IRmJIvEDL
- Eric Rivers is coming off the two best performances of the season, with 117 receiving yards in Week 12 and 97 in Week 10.
- Pitt is 10th in the ACC in passing yards allowed per game against conference opponents (254.8).
- Georgia Tech is No. 1 in the FBS in yards after the catch per reception (6.5), via CFB Graphs.
- The Panthers are allowing 3.2 yards after the catch, which ranks 41st.
- Pitt has allowed an opponent to have a 90+ yard pass catcher in three straight games.
Tennessee WR Chris Brazzell Projection: 71.5 Receiving Yards
No. 20 Tennessee vs. Florida Pick – 7 p.m. ET
BREAKING: Tennessee’s Chris Brazzell II has been named a Biletnikoff Award Semifinalist.
— Rocky Top (@Rockytop) November 17, 2025
pic.twitter.com/jyLEXHdMf9
- Chris Brazzell ranks 10th in the nation in receiving yards (873).
- Brazzell has more than 100 yards in four games this season.
- Florida has allowed an opposing pass catcher to have more than 70 yards in four of its last five games.
- The Gators rank 119th in yards allowed after the catch per reception (4.1).
Make College Football DFS Picks on PrizePicks
Week 13 of college football could reshape the CFB Playoff rankings.
Whether you're watching the SEC matchup between Oklahoma and Missouri or the Big Ten clash featuring USC and Oregon, PrizePicks is the best way to cash in on your college football picks.
Just pick your players — including Arch Manning and Carson Beck — predict More or Less on their stat projections, and get paid if your picks are correct.
Stay locked in on the Playbook for more CFB DFS picks and college football predictions throughout the 2025 season.
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