Ravens vs. Chiefs Prediction, NFL Week 4 Picks: Lamar Jackson, Patrick Mahomes, More

The Ravens and Chiefs are both off to disappointing 1-2 starts to the season, which has landed them in last place in their respective divisions. It’s incredible to think that after this heavyweight matchup, one of these Super Bowl contenders will be 1-3...or, who knows, maybe 1-2-1.

Let’s break down this matchup and highlight three Ravens vs. Chiefs picks for PrizePicks, including Chiefs QB Patrick Mahomes and Ravens QB Lamar Jackson.

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Ravens vs. Chiefs Prediction, Preview for 9/28/25

The Ravens have scored 111 points through three games, but have two losses primarily because their defense has allowed 96 points. The Chiefs have played much better on the defensive side of the ball, giving up a total of just 56 points. However, their offense has scored only 60 points during their slow start.

Baltimore Ravens Preview

Jackson's offense has been generating a lot of big plays in the early going: According to 4for4 Football, they rank second in the league in explosive pass percentage (18.4%) and first in explosive rush percentage (16.4%). That has resulted in them having a high-scoring offense, despite managing the second-fewest total offensive plays in the league.

Kansas City Chiefs Preview

The Chiefs should receive a big boost to their attack with WR Xavier Worthy (shoulder) trending toward a return. They need him in the worst way considering the state of their rushing game. As per 4for4 Football, K.C. has the sixth-worst explosive rush percentage (3.7%) in the league.

Ravens vs. Chiefs Picks for NFL DFS & PrizePicks

Here are three of the top predictions and NFL DFS picks on PrizePicks for Ravens vs. Chiefs. Use this analysis to build your Lineups on PrizePicks NFL for Week 4.

Chiefs QB Patrick Mahomes vs. Ravens Projection: 36.5 Pass Attempts

• Mahomes hasn’t thrown for more than 258 yards in a game this season, but it hasn’t been because of a lack of opportunities. He has attempted at least 37 passes in two of three outings.
• The future Hall of Famer has been throwing often despite Worthy's (shoulder) and Chiefs WR Rashee Rice's (suspension) absences.
• The Chiefs’ lack of explosiveness in their running game has resulted in them having the ninth-fewest rushing attempts in the league.
• The Ravens are averaging 37.0 points per game, which has forced teams to throw a lot against them to try and keep pace. The result has been the Ravens seeing the NFL's second-most pass attempts by an opponent.

Chiefs WR Xavier Worthy vs. Ravens Projection: 41.5 Receiving Yards

• Worthy has been a full participant in practice this week and should immediately be the Chiefs’ top wideout with Rice still serving his suspension.
• While his rookie season got off to a slow start, Worthy posted at least 41 receiving yards in each of his final seven games, excluding a Week 18 matchup against the Broncos in which he logged only one offensive snap.
• The speedy wide receiver also recorded at least 45 receiving yards in all three playoff games, including 157 yards in the Super Bowl.
• The University of Texas at Austin product accounted for 25.1% of the Chiefs’ air yards last season.
• With teams throwing so much against them, the Ravens have given up the second-most passing yards per game.

Ravens QB Lamar Jackson vs. Chiefs Projection: 46.5 Rush Yards

• Jackson has posted at least 6 rushing attempts in two of three games. That included a Week 1 matchup with the Bills in which he ran for 70 yards.
• When the Ravens faced the Chiefs in Week 1 last season, Jackson ran 16 times for 122 yards.
• Including the playoffs, the Ravens’ star QB has faced the Chiefs six times. Across those six games, he has averaged 79.8 rushing yards.
• Jackson has averaged at least 5.5 yards per carry in each of the last six seasons.

Make Ravens vs. Chiefs Picks, Win Cash on PrizePicks

The Ravens and Chiefs will both be trying to avoid 1-3 starts, and Mahomes and Jackson will need to carry their respective squads. Luckily for Mahomes, he could a boost at the wide receiver position should the explosive Worthy return to the fold.

Use Ravens vs. Chiefs picks to help build your NFL Lineups on PrizePicks. Just pick More or Less for at least two NFL player stat projections to build your Lineup on PrizePicks. Check out the Playbook for more NFL DFS picks and analysis all the way through the season.