Rams vs. Jags Prediction, NFL London Game Picks: Matthew Stafford, 2 More

The Rams and Jaguars meet in London for a matchup of 4-2 teams, both in contention in their respective divisions and conferences. The trip marks the fifth international game for the Rams and 14th for the Jaguars, who have made London their second home. The Sunday morning game kicks off at 9:30 a.m. ET on NFL Network.

Below, we'll break down our Rams vs. Jaguars prediction and Week 7 Sunday picks, including the top player picks on PrizePicks real money NFL game, including Rams QB Matthew Stafford and RB Kyren Williams, and Jaguars QB Trevor Lawrence.

Rams vs. Jaguars Prediction, NFL London Week 7 Picks

Los Angeles Rams Preview

• The Rams offense comes into Week 7 ranked third in DVOA offense, per FTN Fantasy. A good part of that is their rushing attack, which is second in DVOA, behind Buffalo. The Rams passing attack comes in ranked sixth in DVOA. 
• LA’s defense allows 306.8 yards per game, eighth-best in the NFL. The pass defense is ninth at 199.0 pass yards per game. Overall, the Rams defense is fifth in DVOA, behind the Falcons, Packers, Texans, and division-rival Seahawks. 
• Per PFF, the Rams have the highest-rated offense in the league and the highest-rated run blocking unit of the 32 teams. They also have the second-highest rated defense. 
• Rams WR Puka Nacua entered Week 6 as the NFL’s leading WR with 588 yards (117.6 per game). He got injured in the second quarter of last week’s game, held to 28 yards and is out this week. Nacua was on the field for 76% of the Rams snaps through the first five games.
• The Rams are 2-2 in International games, having last played in London in 2019. 

Jacksonville Jaguars Preview

• The Jaguars defense has held opponents to 91.5 rush yards per game, eighth best in the NFL. The defense is ranked 15th overall in DVOA. 
• Jacksonville has shown a balanced offense in 2025, ranking 11th in rushing yards per game (124.0) and 15th in passing yards per game (207.0).
• HC Liam Coen's crew has played the most games (13) and have the most wins (7) in International contests, all of which have been played in the UK. 
• The Jags are looking for their first 5-2 start since 2023, when they started 6-2 before losing six of their last nine games for a 9-8 finish. Prior to 2023, the Jags had not started 5-2 since the 2004 season.

Rams vs. Jaguars Picks for NFL DFS & PrizePicks

Here are three Rams vs. Jaguars  player picks for Week 7 for PrizePicks real money NFL game, including Rams QB Matthew Stafford and RB Kyren Williams, and Jaguars QB Trevor Lawrence.  

‍Pick More or Less on these projections on PrizePicks — plus thousands more — to win real money this NFL season.

Rams QB Matthew Stafford Projection vs. Jaguars: 250.5 passing yards

• Rams QB Matthew Stafford has thrown 2+ TD passes in four of six games this season and in 12 of his last 18 games, dating back to last season. 
• In Stafford’s six games this season, he has thrown for 245+ yards in four. 
• Stafford’s 1,684 passing yards is most in the NFL season. 
• The Rams starter has 14 TD passes through six games. Entering Week 7, that’s tied for the third-most in the NFL. 

Rams RB Kyren Williams Projection vs. Jaguars: 69.5 rushing yards

• Rams RB Kyren Williams does not have a 100-yard rushing game this season. In 2024, Williams had four 100+ yard rushing games, including three in his last five regular season games and in one of two postseason games. 
• Williams has rushed for 65+ yards in five of six games this season.
• The Rams RB scored a rushing TD last week against the Ravens, ending a four-game drought without a rushing TD. He was fourth in the NFL last season with 14 rushing TDs, but has 2 this season. 
• The Notre Dame product goes up against a Jaguars defense that ranks eighth in the NFL, allowing 91.5 rush yards per game.  

Jaguars QB Trevor Lawrence Projection vs. Rams: 223.5 passing yards

• Jaguars QB Trevor Lawrence has passed for 220+ yards in four of six games this season.
• Lawrence has failed to throw multiple TD passes in four of the six games here in 2025.
• He had 3 TDs passes vs. the Bengals in Week 2 and 2 TDs last week vs. Seattle. 
• The former Clemson standout's 81.9 QB rating is ranked 26th among 30 qualified QBs entering Week 7.

Make Week 7 Football Picks on PrizePicks

The Rams and Jaguars, both 4-2 on the season, meet in a marquee Week 7 Sunday battle in London, 9:30 a.m. ET on NFL Network. Can the Jaguars keep pace with the red-hot Colts in the AFC South by racking up a win over a 4-2 Rams team? Or will the Rams take control of the NFC West, beating the Jaguars in their home away from home?

As the NFL season enters its seventh week, there's no better place to get real money action with your NFL predictions than on PrizePicks.

There is a wide variety of player stat projections on the NFL board, so you can make predictions on whatever you'd — from yards to field goals. Just pick at least two players and pick More or Less on their stats to build your Lineup on PrizePicks.

Check out the Playbook throughout the NFL season for more NFL predictions for your PrizePicks and NFL DFS Lineups.