Packers vs. Vikings Prediction, Picks for NFL Week 18: Justin Jefferson, More

Minnesota Vikings WR Justin Jefferson runs with the ball against the Chicago Bears.
AP Photo/Kamil Krzaczynski

The Packers (9-6-1) visit the Vikings (8-8) in Sunday’s NFC North finale at U.S. Bank Stadium. Green Bay is prioritizing health and rest ahead of the postseason, while Minnesota is trying to close a frustrating season with a statement win at home. Kickoff is set for 1:00 p. m. ET on CBS.

Below, we’ll dive into a Packers vs. Vikings prediction and picks for Sunday's game. You can make your picks for player projections on PrizePicks and earn real money if you're right. Just predict More or Less on projected stats.

You can also make picks on winners, spreads, and over/unders on PrizePicks Team Picks, now available in 30 states.

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Packers vs. Vikings Prediction, Over/Under, Spread

This is the 131st regular-season matchup between these two NFC North foes, with Green Bay holding a 67-60-3 all-time record. The Vikings come in as the 9.5-point home favorites, with the over/under sitting at 36.5 points — the lowest total this week.​

The Packers are looking to get healthy for their playoff run, resting QB Jordan Love in a meaningless game.

Minnesota has its own injury concerns. Vikings RB Aaron Jones (hip) and TE T.J. Hockenson (shoulder) have been ruled out for Sunday’s regular-season finale.

Packers vs. Vikings Over/Under Spread

The Packers enter Sunday’s game as 9.5-point road underdogs, returning 4.16x payout on PrizePicks Team Picks if they win outright.

The Vikings are home favorites with a 1.21x payout if they win, via PrizePicks Team Picks.

  • Spread: Minnesota Vikings -9.5 
  • Over/Under: 36.5
  • Game Winner Payout: Packers 4.16x | Vikings 1.21x

Team Picks data is live as of writing and is subject to change.

Packers vs. Vikings Prediction on Spread

  • The Packers have been a bettor’s nightmare in 2025, posting a dismal 6-10 against-the-spread record (37.5%).
  • Minnesota enters Week 18 on a hot streak, covering the spread in four consecutive games to pull their ATS record even at 8-8 after a sluggish start.​
  • Defensive coordinator Brian Flores' defense has been the team's saving grace, boasting the NFL's best red zone defense by allowing TDs on just 43.8% of opponent trips inside the 20-yard line.​
  • Ball security remains a glaring issue for the Vikings, with 29 giveaways through 16 games resulting in a -8 turnover differential.​
  • Green Bay has struggled to bounce back from adversity, going a 0-5 ATS following a loss.​

Packers vs. Vikings NFL Week 18 Picks

Here are the top Packers vs. Vikings Week 18 picks on PrizePicks’ real-money NFL game, including projections for QB J.J. McCarthy and WR Justin Jefferson.

Vikings QB J.J. McCarthy vs. Packers Projection: 184.5 Pass Yards

  • Green Bay ranks top 10 in passing yards allowed overall but has been softer away from Lambeau Field, giving up the 12th-most YPG (232.6) on the road.
  • McCarthy could see a favorable game script with the Packers locked into the No. 7 seed, as they could limit starters' playing time.
  • Despite an underwhelming season, the Vikings' QB1 flashed his ceiling just three weeks ago against the Cowboys with a career-high 250 passing yards.​
  • Green Bay's secondary has sprung leaks recently, allowing 219.7 passing YPG during their three-game skid.
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Vikings WR Justin Jefferson vs. Packers Projection: 66.5 Receiving Yards

  • The Packers' defense struggles in coverage against opposing WRs, yielding 477 receiving yards (155.9 YPG) to them over their last three games.
  • Minnesota's superstar WR dominates this divisional matchup historically, averaging 76.2 YPG in 10 career meetings against Green Bay.
  • The Packers play zone at one of the league’s highest rates (78.5%, via Sharp Football Analysis) and with starters perhaps resting, Jefferson could thrive. He's among the NFL's best in yards per route run against zone coverage (2.37).
  • Minnesota’s game plan may feature a heavy dose of Jefferson, who needs exactly 53 receiving yards to extend his career streak of 1,000-yard seasons.

Make Packers vs. Vikings NFL Week 18 Picks on PrizePicks

This Packers vs. Vikings NFL Week 18 matchup presents plenty of opportunities to put your NFL knowledge to the test. Despite an up‑and‑down year, both McCarthy and Jefferson should aim to close strong for Minnesota against Green Bay in Week 18.

You can make Packers vs. Vikings picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.

Keep it locked in here with the Playbook for NFL picks, predictions, and news every day.


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about the author

Garrett Kerman is a seasoned sports writer who has written for numerous outlets over the years from ClutchPoints, to Ballislife, to OutKick Sports. He also goes by the name The Fight Analyst where he has been a prominent voice in combat sports. However, he still maintains his voice in all sports like NFL, NBA, and MLB bringing viewers the best in coverage and analysis.

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