The Miami Hurricanes are waiting for their opponent in the National Championship, and it'll be a Big Ten squad.
Top-ranked Indiana (14-0) rolled past Alabama in the Rose Bowl, 38-3, marking their 25th win in 27 games under head coach Curt Cignetti. Oregon (13-1), meanwhile, shut out an explosive Texas Tech offense in the Orange Bowl, 23-0.
It's a rematch of October's 30-20 Hoosiers win, which saw them score the final 10 points on the road. With that in mind, let’s look at an Oregon vs. Indiana spread prediction for Friday’s Peach Bowl at Mercedes-Benz Stadium in Atlanta, kicking off at 7:30 p.m. ET on ESPN.
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Oregon vs. Indiana Prediction, Spread, Over/Under
Both teams own 9-5 against-the-spread records, which includes a cover in the last round of the College Football Playoff.
Oregon vs. Indiana Over/Under, Spread
The Hoosiers enter this matchup as 3.5-point favorites, returning a 1.51x payout on PrizePicks Team Picks if they win outright.
The Ducks are underdogs with a 2.43x payout if they win, via PrizePicks Team Picks.
- Spread: Indiana Hoosiers -3.5
- Over/Under: 49.5
- Game Winner Payout: Ducks 2.43x | Hoosiers 1.51x
(Team Picks data is live at the time of writing and is subject to change)
Oregon vs. Indiana Prediction on Spread for Peach Bowl, CFP Semis
Here are some stats to know to get you set for Oregon vs. Indiana tonight.
- The Ducks are listed as an underdog for the second consecutive week after being favored in their previous eight games.
- Oregon won as a 4.5-point road dog at Penn State in late September, then closed as a 1.5-point dog against Texas Tech and held the Red Raiders to 215 yards in last week’s shutout.
- All five of Indiana’s ATS losses came as a favorite of nine or more points. In their two opportunities as a 7.5-point favorite or fewer, the Hoosiers went 2-0.
- Both teams rank in the top four of net EPA/Play offensively; the Hoosiers sit third, followed by the Ducks at fourth.
- Since joining the Big Ten in 2024, Oregon is 18-2 against conference opponents. Their two defeats came to Ohio State in last year’s CFP Quarterfinals and Indiana at home in Week 7. Indiana is 18-1 vs. the Big Ten under Cignetti.
- In the first matchup in Eugene, Heisman Trophy winner Fernando Mendoza threw for 215 yards and the go-ahead TD to WR Elijah Sarratt with less than seven minutes left.
- Oregon QB Dante Moore was held to his lowest QBR (35.1) against Indiana, also tossing 2 INTs and mustering just 186 passing yards.
- Underdogs are 6-3 ATS in the CFP, with five outright victories. The only favorite that failed to cover in a win was Oregon as 20.5-point favorites in a 51-34 victory over James Madison.
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Make Oregon vs. Indiana CFP Picks on PrizePicks
Can Oregon grab revenge against Indiana and a spot in the National Championship at Friday’s Peach Bowl? There’s never been a better time to add to the excitement of every CFB moment than with PrizePicks.
You can make your Oregon vs. Indiana Peach Bowl and other CFP picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.
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