The Denver Nuggets (33-18) visit Madison Square Garden on Wednesday night to face the New York Knicks (32-18) in a marquee interconference showdown.
Denver looks to snap a two-game skid and reset their momentum behind All-Star C Nikola Jokic, while New York aims to defend home court and extend its seven-game winning streak. Tip-off is set for 7:00 p.m. ET on ESPN.
Below, we’ll break down our Nuggets vs. Knicks prediction and spread for Wednesday night’s game. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Nuggets vs. Knicks Prediction, Spread
The Nuggets enter Wednesday’s contest looking to rebound from a tough 124–121 loss to the Pistons on Tuesday. They remain near the top of the West at 33–18, but are navigating a rough patch with key injuries. The Nuggets will be without F Aaron Gordon, who remains sidelined with a right hamstring strain, a loss that continues to test the team’s defensive versatility.
New York, conversely, is one of the league’s hottest teams, riding a seven-game surge to 32–18. The Knicks have climbed up the Eastern Conference standings, anchored by dominant home performances at Madison Square Garden, though they are managing their own depth issues with SG-SF Josh Hart and G Miles McBride both questionable for tonight’s contest.
This is their first meeting this season, with a return date in Denver set for March. New York won the most recent meeting in January 2025, 122–112, but Denver still leads the all-time series 52–49.
Nuggets vs. Knicks Over/Under, Spread
The Nuggets enter Wednesday’s game as 7.5-point road underdogs, returning a 2.94x payout on PrizePicks Team Picks if they win outright.
The Knicks are home favorites with a 1.35x payout if they win, via PrizePicks Team Picks.
- Spread: New York Knicks -7.5
- Over/Under: 226.5
- Game Winner Payout: Nuggets 2.94x | Knicks 1.35x
Team Picks data is live at the time of writing and is subject to change.
Nuggets vs. Knicks Injury Report
Let’s dive into the full Nuggets vs. Knicks injury report for Wednesday, via NBA.com.
Nuggets Injury Report
- F Cam Johnson (knee) – Doubtful
- G Tamar Bates (foot) – OUT
- F Aaron Gordon (hamstring) - OUT
Knicks Injury Report
- F Kevin McCullar (calf) - Questionable
- C Mitchell Robinson (ankle) - Probable
- G Mohamed Diawara (ankle) - Questionable
- G-F Josh Hart (undisclosed) - Questionable
- G Miles McBride (ankle) - Questionable
Nuggets vs. Knicks Prediction on Spread
Here are some stats to know to help you make your Nuggets vs. Knicks prediction on Wednesday, February 4.
- The Nuggets are 30-21-0 ATS (58.8%), one of the league’s best marks, while the Knicks are 28-23-0 ATS (54.9%).
- Denver is 18-9-0 ATS on the road (66.7%), ranking among the league’s elite away from Ball Arena.
- New York has been rock-solid at Madison Square Garden, posting an 18-8-0 ATS record (69.2%) at home.
- Without Aaron Gordon, Denver's defense rating has dipped to 121.5, creating more pressure on Jokic and PG Jamal Murray to carry the offensive load and outscore opponents.
- The Knicks have covered in five of the last six meetings with Denver.
Nuggets vs. Knicks for PrizePicks Today: Wednesday, February 4
Knicks PG Jalen Brunson vs. Nuggets Projection: 25.5 Points
- Brunson is averaging 27.1 points per game this season on 47.1% shooting while handling 20.4 field goal attempts per contest. He’s established himself as New York's primary offensive weapon with a 30.1% usage rate.
- He has historically dominated Denver, averaging 26.3 PPG over his last three matchups against the Nuggets, including a 30-point performance in their most recent meeting on January 29, 2025.
- Denver's perimeter defense has been porous this season, ranking 23rd in defensive rating at 116.7 and allowing 117.9 points per 100 possessions.
- With Hart and McBride potentially sidelined, Brunson's usage and shot volume could be elevated even further as he shoulders more of the offensive load.
Nuggets C Nikola Jokic vs. Knicks Projection: 43.5 Pts+Rebs+Asts
- Jokic averages 51.7 combined points, rebounds, and assists (29.1 PPG, 12.1 RPG, 10.5 APG) through 35 games this season.
- Over his last 10 games, Denver’s star center posted 49.9 PRA (28.8 points, 11.4 rebounds, 9.7 assists per game).
- New York allows at 187.3 PRA per game, and Jokic averages 24.8 points, 9.6 rebounds, and 7 assists (41.4 PRA) in his last five against the Knicks.
- The Joker’s 29.3% usage rate anchors Denver's offense entirely, and since coming back from injury without Gordon in the lineup, he’s averaging 23.7 points, 11.3 rebounds, and 5.7 assists in his last three.
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