NFL Week 5 gives us a plethora of compelling matchups, among them the undefeated Philadelphia Eagles hosting the Denver Broncos; the 3-1 Seattle Seahawks and 3-1 Tampa Bay Buccaneers throwing down; the surprising Indianapolis Colts, off their first loss of the season, hosting the Las Vegas Raiders; and the Kansas City Chiefs looking for their third straight win down in Jacksonville, where they'll face the 3-1 Jaguars.
We'll dive deep into four Week 5 games with team and player stats offering key insights to make your picks and predictions this week, whether you're playing fantasy football or NFL DFS on PrizePicks.
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Broncos vs. Eagles Picks & Stats to Know
- The Eagles have won 20 of their last 21 games, with the only loss being to the Commanders last December, a game in which QB Jalen Hurts left with an early injury. The last team to win 20 of 21 games was the Kansas City Chiefs over the 2019-20 season, which included their Super Bowl title.
- The Eagles are 4-0 for the third time in the last four seasons. They started 8-0 in 2022 and 5-0 in 2023.
- Hurts has 1+ rushing TD in three of four games this season and in six of his last seven overall, including the postseason. The only one he didn’t score in was last week vs. the Buccaneers.
- Through the first 10 quarters of this season, Hurts had 0 TD passes. He has 5 passing TDs in his last six quarters, tossing 3 TDs in the second half of Week 3 against the Rams, plus 2 more last week vs. the Bucs.
- Eagles RB Saquon Barkley has rushed for 60, 88, 46, and 43 yards in the four games this season. In 20 games played with the Eagles last year, Barkley had 90-plus yards in 15 outings.
- Including the postseason, Eagles WR A.J. Brown has failed to reach 50 yards receiving in seven of his last nine games. He has one game of 100-plus yards during that stretch.
- Broncos QB Bo Nix passed for 176, 206, and 153 yards in his first three games this season before tossing for a career-high 326 yards on Monday night against the Bengals. At the end of his rookie season, Nix passed for 250+ yards in five of his last seven games.
- Nix has thrown at 1+ TD passes in 13 consecutive games. Nine of the 13 games have been 2+ TD passes.
- Broncos RB snap counts through four weeks: J.K. Dobbins 137 (51.3 pct), R.J. Harvey 89 (33.3 pct), Tyler Badie 37 13.9 pct).
Broncos vs. Eagles Picks to Target
Broncos vs Eagles projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Eagles QB Jalen Hurts - 1.5 passing TDs
- Eagles RB Saquon Barkley - 81.5 rushing yards
- Broncos QB Bo Nix - 221.5 passing yards
Buccaneers vs. Seahawks Picks & Stats to Know
- Buccaneers QB Baker Mayfield had 2 passing TDs last week against the Bengals on Monday night, the ninth time in 10 games with 2+ passing TDs. He had 2+ passing TDs in 13 of 18 games last season, including the playoffs, and now in 28 of his 41 games played with the Bucs.
- Bucs WR MIke Evans was out last week, while WR Chris Godwin returned. The one constant has been rookie WR Emeka Egbuka, who has seen 4+ targets in all four games, with 4 TDs.
- Egbuka’s targets have increased each week: 6 targets Week 1, 7 targets Week 8, 8 targets Week 3 and 10 targets Week 4. He leads the Bucs WRs with a 22.3 pct target share.
- RB Bucky Irving has a sprained foot and is in a walking boot. He leads the Buccaneers backfield with 70.2 pct of the team’s snaps. Rachaad White (31.6 pct) and Sean Tucker (3 total snaps) are the only other Bucs RBs to receive snaps this season.
- Seattle QB Sam Darnold has thrown 1-plus passing TD in three of four games this season and in 11 of the past 13 overall, including his games with the Vikings.
- Jaxson Smith-Njigba has seen his output decrease in every game this season:
- Week 1: 13 targets, 9 receptions, 124 yards
- Week 2: 10 targets, 8 receptions, 103 yards
- Week 3: 6 targets, 5 receptions, 96 yards (TD)
- Week 4: 5 targets, 4 receptions, 79 yards
- The Seahawks defense ranks first in defensive DVOA, per FTN Fantasy and the offense ranks eighth in the league.
- Seahawks RB snap counts through four weeks: Kenneth Walker III 107, Zach Charbonnet 97, rest of team 25.
Buccaneers vs. Seahawks Picks to Target
Buccaneers vs Seahawks projections are from the PrizePicks real money NFL game.
- Buccaneers QB Baker Mayfield - 1.5 passing TDs
- Seahawks QB Sam Darnold - 225.5 passing yards
- Buccaneers WR Emeka Egbuka - 61.5 receiving yards
Raiders vs. Colts Picks & Stats to Know
- Colts QB Daniel Jones has thrown for 225-plus yards in all four games this season with 1+ TD in each game. In his final 16 games with the Giants over the 2023 and 2024 seasons, he reached 225 yards five times.
- Indy RB Jonathan Taylor leads the NFL with 414 rushing yards. He has rushed for 100-plus in the two of his last three games and in six of his last eight games overall.
- One reason for the Colts offensive success has been its OL. Per PFF, the Colts OL ranks fourth in the league in run blocking and 15th in pass blocking, which leads to them having the fifth-ranked offense.
- The Colts have the third-most efficient offense according to DVOA, just behind the Bills and Rams.
- On the other side, the Raiders offense comes in at 26th in DVOA, with their passing offense 27th and rush offense 25th.
- Raiders rookie RB Ashton Jeanty recorded his first 100-yard rushing game last week as part of a 240-yard rushing game by the Raiders. It was the most rushing yards by the Raiders since Week 12 of the 2022 season, when they had 283 rushing yards against Seattle, who was coached by current Raiders coach Pete Carroll.
- After opening up with a 103-yard receiving game Week 1, Raiders TE Brock Bowers has been held to 38, 38 and 46 yards over his last three games. In his rookie season in 2024, he never went three straight games without hitting 50 receiving yards.
Raiders vs. Colts Picks to Target
Raiders vs. Colts projections are from the PrizePicks real money NFL game.
- Colts QB Daniel Jones - 229.5 passing yards
- Colts RB Jonathan Taylor - 87.5 rushing yards
- Raiders TE Brock Bowers - 53.5 receiving yards
Chiefs vs. Jaguars Stats to Know
- The Chiefs had won 17 consecutive one-score games before losing by 6 to the Chargers in Week 1 and 3 to the Eagles in Week 2.
- K.C. put up 382 yards last week vs. the Ravens, the first time they topped 350 yards since last year’s AFC Championship win over Buffalo and fifth time over the last 16 games.
- Including postseason, Chiefs TE Travis Kelce has failed to reach 70-plus yards receiving in 13 of his last 15 games.
- Chiefs QB Patrick Mahomes had 4 TD passes last week vs. the Ravens after being held to 1 in each of the first three games of the season. Dating back to last season, Mahomes has multiple TD passes in only two of his last seven games. Prior to that, Mahomes had thrown 2+ passing TDs in 10 of 20 games.
- Chiefs WR Xavier Worthy made his return to the lineup after the Week 1 injury and made an immediate impact with 5 catches for 83 yards. Last year, Worthy had 50-plus yards receiving in six of his last ten games.
- The Jaguars have won three of their first four games of the season for the first time since 2018 and only the second time since 2008.
- Jaguars WR Brian Thomas Jr. has failed to go over 55 yards receiving in any game this season after going for 55-plus in 12 of 17 games in his rookie season, including the last seven games of the season.
- Jaguars RB Travis Etienne Jr's 394 rushing yards are third-most in the NFL this season. His 6.1 yards per rush leads all RBs and is second overall, behind Jets QB Justin Fields.
Chiefs vs. Jaguars Picks to Target
Chiefs at Jaguars projections are from the PrizePicks real money NFL game.
- Chiefs QB Patrick Mahomes - 1.5 passing TDs
- Chiefs WR Xavier Worthy - 56.5 receiving yards
- Jaguars WR Brian Thomas Jr. - 56.5 receiving yards
Pick More or Less on NFL Week 5 Stats
The undefeated Eagles host the 2-2 Denver Broncos, the Buccaneers and Seahawks meet as 3-1 teams in an NFC battle, the Colts try to bounce back from their first L of the season, and Chiefs QB Patrick Mahomes looks to give Kansas City its third dub of the year, traveling to Jacksonville Monday night.
We hope these Week 5 picks and stats to know can help you make your picks and predictions on PrizePicks' real money NFL game.
Simply pick your players, predict More or Less on their Week 5 stats, and win cash when you're right. It's the simplest way to play NFL DFS, all season long.
