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NFL Week 3 Picks and Stats to Know: Saquon Barkley for 200-Plus Yards vs. Rams?

Eagles RB Saquon Barkley runs the ball in an NFL game.
AP Photo/Ed Zurga

NFL Week 3 gives us a plethora of compelling matchups, with the Los Angeles Rams traveling to Philadelphia for a rematch of their 2024 Division Round game; the Denver Broncos heading to Los Angeles in an AFC West showdown; QB Patrick Mahomes and his Chiefs looking to pick up their first win of the season on the road against the winless Giants; and a potential Super Bowl preview on Monday Night Football, pitting Lamar Jackson and the Ravens against Jared Goff and the Lions.

We'll dive deep into four Week 3 games with team and player stats to bring you key insights to make your picks and predictions this week, whether you're playing fantasy football or NFL DFS on PrizePicks.

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Denver Broncos at Los Angeles Chargers Picks & Stats to Know

  • The Chargers, under first-year coach Jim Harbaugh, swept the season series with the Broncos last season. Prior to 2024, the Bolts had not swept the season series since 2010.
  • The Chargers are looking for their first 3-0 start since starting 4-0 back in 2002. 
  • Chargers QB Justin Herbert is 5-4 in nine career games against the Broncos. In those nine games, he has averaged 244.3 passing yards with 13 TDs in the air and 7 INTs.
  • Broncos second-year QB Bo Nix lost both his starts facing the Chargers in 2024. In the first game, he threw for 216 yards with 2 TDs and 1 INT. In the rematch, he racked up 263 yards and 2 TDs, with nary a pick to be seen
  • Chargers kicker Cameron Dicker had 5 FGs over the two games last season, including the famous “Fair Catch Kick” at the end of the first half. He is 10-11 on field goals in five career games against the Broncos. 
  • This is a matchup between two top-ten defenses. The Chargers are third in the NFL in scoring defense (15.0), seventh in total defense (282.5 yards) and tops in red zone defense. The Broncos defense, which finished 2024 as the top NFL defense, is tenth in total yards and ninth in pass defense. 
  • Chargers WR Quentin Johnston has 70-plus receiving yards in his last three regular season games, along with 3 TDs.
  • Broncos RB snap counts through two weeks: J.K. Dobbins, 66 (24 in Week 2), R.J. Harvey, 41 (19 in Week 2), and Tyler Badie, 27 (13 in Week 2).
  • Chargers RB snap counts through two weeks: Omarion Hampton, 88, Najee Harris, 32.

Broncos vs. Chargers Picks to Target

Broncos vs Chargers projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.

  • Broncos QB Bo Nix - 218.5 passing TDs
  • Chargers QB Justin Herbert - 234.5 passing yards
  • Chargers WR Quentin Johnston - 46.5 receiving yards

Los Angeles Rams at Philadelphia Eagles Picks & Stats to Know

  • This is a rematch of the Eagles 28-22 Divisional Round win last season. In that game, Philly RB Saquon Barkley rushed for 205 yards and 2 TDs (68-yard TD and 78-yard TD).
  • In that same game, Rams RB Kyren Williams had 106 yards rushing and QB Matthew Stafford passed for 324 yards and a pair of TDs.
  • The teams also met in the regular season, where Barkley rushed for 255 yards and 2 TDs, while Matthew Stafford tossed 2 TDs.
  • The Eagles have won 9 of the last 10 matchups between the two teams, including postseason. 
  • Eagles QB Jalen Hurts passed for 179 yards with 1 TD in the regular season meeting and 128 yards in the postseason tilt. He added 70 rush yards and a rushing TD in the playoff game. 

Rams at Eagles Picks to Target

Rams at Eagles projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.

  • Eagles QB Jalen Hurts - 0.5 rushing+receiving TDs. 
  • Eagles RB Saquon Barkley - 89.5 rush yards
  • Rams QB Matt Stafford - 220.5 passing yards

Kansas City Chiefs at New York Giants Picks & Stats to Know

  • The Chiefs are 0-2 for the first time since 2014, when Alex Smith was their QB and Patrick Mahomes was a freshman at Texas Tech. They were last 0-3 at the start of the 2011 season. 
  • The Giants are 0-2 for the tenth time in the last 13 years (since 2014) and for the second straight season. 
  • This will be Chiefs QB Patrick Mahomes' second start against the Giants and first on the road. Mahomes threw for 275 yards with a TD (to Tyreek Hill) and a pick in the win. 
  • Giants QB Russell Wilson has faced the Chiefs seven previous times, losing five. He averaged 190.3 yards per games with 13 TDs and 5 INTs in the seven games, adding 3 rushing TDs. 
  • The Chiefs had won 17 consecutive one-score games before losing by 6 to the Chargers in Week 1 and three to the Eagles last week.  
  • The Chiefs were held to 294 yards last week against the Eagles after mustering 347 yards against the Chargers Week 1 They have now failed to reach 350 yards of total offense in 10 of the last 14 games, including postseason. 
  • Including postseason, Chiefs TE Travis Kelce has failed to reach 70-plus yards receiving in 11 of his last 13 games. 

Chiefs at Giants Picks to Target

Chiefs at Giants projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.

  • Chiefs QB Patrick Mahomes - 0.5 passing TDs
  • Chiefs TE Travis Kelce - 47.5 receiving yards
  • Giants QB Russell Wilson - 219.5 passing yards

Detroit Lions at Baltimore Ravens Picks & Stats to Know

  • Including playoffs, the Ravens have scored 25-plus points in their last eight games and in 16 of their last 19 games. 
  • Including playoffs, the Lions have scored 30-plus points in seven of their last eight games. 
  • Lions WR Amon-Ra St. Brown has had 6-plus targets in 13 consecutive games, including the postseason. 
  • This is a matchup of two top-five offenses. The Ravens lead the NFL in points per game at 40.5, while the Lions are third at 32.5.
  • The Lions are fifth in the NFL in total offense and passing offense and the Ravens lead the NFL at 6.54 yards per play.
  • Ravens RB Derrick Henry had 11 touches last week for 23 total yards, both the least he has had in a Ravens uniform. 
  • Ravens QB Lamar Jackson has rushed for 60-plus yards in six of his last nine games, including postseason. 

Lions at Ravens Picks to Target

Lions and Ravens projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.

  • Lions WR Amon-Ra St. Brown - 62.5 receiving yards
  • Ravens QB Lamar Jackson - 48.5 rush yards
  • Ravens RB Derrick Henry - 87.5 rush yards

Pick More or Less on NFL Week 3 Stats

The Rams and Eagles meet six months after their Divisional Round clash, AFC West rivals Broncos and Chargers do battle in Los Angeles, and Chiefs QB Patrick Mahomes looks to give Kansas City its first dub of the season. And lest we forget, the Lions and Ravens give us a potential Super Bowl preview on Monday night.

We hope these Week 3 picks and stats to know can help you make your picks and predictions on PrizePicks real money NFL game.

Simply pick your players, predict More or Less on their Week 3 stats, and win cash when you're right. It's the simplest way to play NFL DFS, all season long.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

David Bearman spent 18 years with ESPN in their Stats & Information Department and overseeing their betting content. From 2023-25, he served as Chief Content Officer of Pro Football Network, overseeing all content, including coverage of Super Bowls 58 and 59. He is also the Founder of Betting with Bearman, a 3x a week betting newsletter and weekly podcast on Bleav Podcast Network.

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