NFL Week 2 gives us a plethora of compelling matchups, with the Philadelphia Eagles traveling to Kansas City for an early season Super Bowl rematch; the Denver Broncos heading to Indianapolis in a showdown between two teams that won Week 1; QB Dak Prescott and his Cowboys looking to continue their domination of the Giants; and a Monday Night Football clash pitting Buccaneers' veteran QB Baker Mayfield against third-year Texans signal caller C.J. Stroud.
We'll dive deep into four Week 2 games with team and player stats to bring you key insights so you can make your picks and predictions this week, whether you're playing fantasy football or deep diving into NFL DFS on PrizePicks.
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Denver Broncos at Indianapolis Colts Stats to Know
- The last time the Colts started 2-0 (2009), Peyton Manning was behind center. They won the next 12 games, before losing to the Saints in the Super Bowl.
- The Colts scored on all seven of their possessions on Sunday vs. Miami. Per the Elias Sports Bureau, they are the first team since 1978 to score on every one of their possessions in a game.
- Statistically speaking, Daniel Jones’ 115.9 passer rating and 87.5 QBR (ESPN) ranked sixth-best in his career.
- The Broncos D picked up where they left off last season (No. 1 defense in 2024 EPA per play), holding Cam Ward and the Titans to 7 first downs, while registering 6 sacks.
- Colts RB Jonathan Taylor has only faced the Broncos once, when he rushed for 107 yards on 22 carries in last year's Week 15 matchup. Taylor was one of only three RBs to get 100-plus yards vs. the Broncos defense last season (Kenneth Walker III in Week 1 and Derrick Henry in Week 9).
- In that Week 15 matchup, Colts WR Michael Pittman Jr. had 58 receiving yards on 6 catches. No skill player other than the previously mentioned Taylor had more than 50 yards.
- Broncos QB Bo Nix had 3 TD passes and 3 INTs in Denver's Week 15 win last season.
- Broncos RB snap counts in Week 1 win over Titans: J.K. Dobbins 40, R.J. Harvey 22, Tyler Badie 14.
Broncos vs. Colts Picks to Target
Broncos vs. Colts projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Colts RB Jonathan Taylor: 73.5 rushing yards
- Broncos QB Bo Nix: 0.5 passing TDs
- Broncos RB J.K. Dobbins: 46.5 rushing yards
New York Giants at Dallas Cowboys Stats to Know
- The Cowboys have won eight straight and 15 of the last 16 vs. the Giants dating back to the 2017 season. That includes eight straight in Dallas, where the G-Men have not won since 2016.
- Dak Prescott has taken 13 of 15 meetings vs. the Giants, including 13 straight, racking up 29 TDs (1.9 per game) and 8 INTs in the process, while passing for 261.0 yards per game.
- The Giants offense was held to 231 yards in Week 1 vs. the Commanders. It was the sixth time in the last eight games in which the Giants offense did not top 250 total yards.
- Giants QB Russell Wilson has failed to reach 250 passing yards in six consecutive regular season games, counting last season with Pittsburgh.
- Although Wilson has not faced the Cowboys since 2020, he has had success against them, winning five of the seven matchups with 12 passing TDs and 2 INTs.
- Cowboys WR CeeDee Lamb has seen 10-plus targets in eight of his last 11 games.
Giants at Cowboys Picks to Target
Giants vs. Cowboys projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Cowboys QB Dak Prescott: 1.5 passing TDs
- Cowboys WR CeeDee Lamb: 82.5 receiving yards
- Giants QB Russell Wilson: 0.5 passing TDs
Philadelphia Eagles at Kansas City Chiefs Stats to Know
- This is the ninth time the last two Super Bowl combatants have reconnected in the following regular season. In the previous eight instances, the team that won the Super Bowl took the rematch. Only the 1993 Bills (vs. Cowboys) and 1970 Vikings (vs. Chiefs) avenged their Super Bowl loss.
- Despite the Super Bowl blowout, Eagles RB Saquon Barkley was held to 57 yards on 25 rushes (2.3 yards per rush) vs. the Chiefs. The 2.3 yards per rush were lowest vs. any opponent, including playoffs, since he joined the Eagles in 2024. His longest run was 10 yards, tied for lowest of any game last season.
- The Chiefs had won 17 consecutive one-score games before losing by 6 to the Chargers last week.
- Super Bowl MVP Jalen Hurts ran for a game-high 72 yards with a TD and passed for another 221 yards with 2 passing TDs in the Super Bowl win.
- The Chiefs offense mustered 275 total yards in the Super Bowl, with Chiefs WR Xavier Worthy accounting for 157 of them, along with 2 receiving TDs. He is questionable to play on Sunday, so the returning production leaders from the last time these teams met would be TE Travis Kelce (9 receiving yards) and QB Patrick Mahomes (25 rush yards).
- The Chiefs were held to 347 yards against the Chargers in Week 1 and have now failed to reach 350 yards of total offense in nine of their last 13 games, including postseason.
- Mahomes has played four career games vs. the Eagles — two of which were Super Bowls — during which he tossed 13 TDs and 4 picks.
- Hurts has been the opposing QB in all four of those meetings and has 6 rushing TDs to go along with 5 passing TDs and 2 INTs, Hurts completed between 63-77% of his passes in all four games.
Eagles at Chiefs Picks to Target
Eagles at Chiefs projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Eagles QB Jalen Hurts: 0.5 rushing+receiving TDs.
- Chiefs QB Patrick Mahomes: 2.5 passing TDs
- Eagles RB Saquon Barkley: 85.5 rush yards
Tampa Bay Buccaneers at Houston Texans Stats to Know
- The Buccaneers are looking to start 2-0 for the fifth straight season, which would extend their franchise record.
- The Texans hope to avoid their third 0-2 start since 2020.
- Dating back to last season, over the last eight games, the Texans, including the postseason, have topped 23 points one time, that being in their playoff win vs. the Chargers.
- Texans RB snap counts in Week 1 loss to Rams: Nick Chubb 32, Dare Ogunbowale 17, Dameon Piece 7, and Woody Marks 7.
- Buccaneers rookie WR Emeka Egbuka shined in his NFL debut with 4 catches for 64 yards and 2 TDs.
- The Buccaneers defense allowed 97.8 rush yards per game last year, the fourth-fewest of any NFL team. In 2023, they allowed 95.3, which was fifth-fewest. In their first meeting vs. the Falcons, they held Atlanta RB Bijan Robinson to 24 yards and the Atlanta offense to 69 total rush yards.
- C.J. Stroud has failed to reach 250 passing yards in eight of his last nine games and 10 of his past 12.
Buccaneers at Texans Picks to Target
Buccaneers and Texans projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Texans QB C.J. Stroud: 223.5 passing yards
- Buccaneers WR Emeka Egbuka: 59.5 rushing yards
- Buccaneers QB Baker Mayfield: 242.5 passing yards
Pick More or Less on NFL Week 2 Stats
The Eagles and Chiefs meet six months after their Super Bowl LIX clash, division rivals Giants and Cowboys do battle in Dallas, Buccaneers QB Baker Mayfield looks to give Tampa Bay its fifth straight 2-0 start in a Monday Night showdown with the Texans, and the Broncos and Colts look to get to 2-0 as they square off in Indy.
We hope these Week 2 stats to know can help you make your picks and predictions on PrizePicks real money NFL game.
Simply pick your players, predict More or Less on their Week 2 stats, and win cash when you're right. It's the simplest way to play NFL DFS, all season long.