NFL Week 17 Picks for PrizePicks, NFL DFS: Will Saquon Barkley Roast The Bills?

Eagles RB Saquon Barkley runs a football in an NFL game.
AP Photo/Matt Slocum

The Week 17 Sunday slate isn’t exactly jam-packed after five total games were played across Thursday and Saturday. However, there are still some superstars who could be primed for juicy stat lines, among them Bengals WR Ja’Marr Chase in his matchup with the Cardinals and Eagles RB Saquon Barkley in his battle with the Bills.

Below, we'll discuss Chase and Barkley, and get into more of the top Week 17 NFL DFS picks for PrizePicks, including some quick NFL DFS picks to keep in mind.

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Quick PrizePicks Picks for NFL Week 17

Here are some quick PrizePicks DFS picks for NFL Week 17, including projections for pass yards, rush yards, and receiving yards.

Cardinals QB Jacoby Brissett vs. Bengals Projection – 254.5 Pass Yards

  • Despite throwing for just 203 yards in a 26-19 loss to the Falcons last week, Cardinals QB Jacoby Brissett has tossed for at least 258 yards in eight of his 10 starts.
  • The veteran signal caller averages 41.6 pass attempts over 10 games since taking over as the Cardinals’ starter.
  • The Bengals have allowed the third-most yards per pass attempt (8.16) in the league.

Giants RB Tyrone Tracy Jr. vs. Raiders Projection – 59.5 Rush Yards

  • Giants RB Tyrone Tracy Jr. has had at least 15 carries in four of his last five games. The one game that he didn’t, he left early because of injury.
  • Taking advantage of the additional work, he ran for at least 62 yards in all four games.

Raiders WR Tre Tucker vs. Giants Projection – 48.5 Receiving Yards

  • The Raiders placed TE Brock Bowers (knee) on injured reserve this week. He accounted for 19.9% of the Raiders’ targets this season.
  • Not far behind Bowers is Raiders WR Tre Tucker, who has an 18.1% target share.
  • The Giants have permitted the fifth-most yards per target to wide receivers (8.45) in the league.

NFL Week 17 Picks for PrizePicks, NFL DFS

Here are the top NFL DFS picks for Week 17. Player projections via the PrizePicks real money NFL game.

Bengals WR Ja’Marr Chase vs. Cardinals Projection – 87.5 Receiving Yards

  • Chase hauled in 9 of 11 targets for 109 yards in a 45-21 win over the Dolphins in Week 16.
  • Since Bengals QB Joe Burrow returned from injury, the star wide receiver has racked up at least 109 receiving yards in three of four games.
  • Chase has a 31.0% target share for the Bengals and has accounted for 35.3% of their air yards.
  • The Cardinals have allowed the tenth-most passing yards per game (224.1) in the league.

Eagles RB Saquon Barkley vs. Bills Projection – 83.5 Rush Yards

  • The Eagles have given Barkley at least 20 rush attempts in three straight games. In two, he finished with at least 122 rushing yards.
  • The former Giant has 10 games with at least 18 carries this season.
  • While he hasn’t been as efficient as he was in 2024, Barkley has already rushed for over 1,000 yards, the fifth season of his career with at least 1,000 yards on the ground.
  • According to RotoWire, the Bills have allowed the third-most yards per carry to running backs (5.21) in the league.

Dolphins RB De’Von Achane vs. Buccaneers Projection – 26.5 Receiving Yards

  • Dolphins RB De’Von Achane has recorded at least 28 receiving yards in seven of his 15 games.
  • With the Dolphins hurting at wide receiver, their star running back has a 19.8% target share.
  • The speedster is averaging 8.2 yards after the catch.
  • Per RotoWire, the Buccaneers have allowed 9.35 yards per target to running backs, most in the league.

Raiders RB Ashton Jeanty vs. Giants Projection – 69.5 Rush Yards

  • Raiders RB Ashton Jeanty almost helped the Raiders pull off an upset over the Texans last week, rushing 24 times for 128 yards and 1 TD. He also had a 60-yard TD reception in the 23-21 loss.
  • The rookie running back has been given at least 20 rushing attempts in three games this season; in each, he ran for at least 75 yards.
  • The Giants have allowed the second-most rushing yards per game (150.9) in the league.
  • New York has permitted a single running back to rush for at least 80 yards against them in five of their last seven games.

Cardinals RB Michael Carter vs. Bengals Projection – 47.5 Rush Yards

  • Cardinals RB Michael Carter has taken over as the starter at the position with RB Bam Knight (ankle) and RB Trey Benson (knee) on injured reserve.
  • After rushing 14 times for 56 yards in a 40-20 loss to the Texans in Week 15, Carter racked up 65 yards on 11 carries in a 26-19 loss to the Falcons in Week 16.
  • The former fourth-round pick has rushed for at least 51 yards in all three games in which he has received at least 11 rushing attempts this season.
  • The Bengals have allowed an NFL-high 156.0 rushing yards per game.

Colts QB Philip Rivers vs. Jaguars Projection – 0.5 INT

  • After attempting 27 passes in his first start with the Colts, QB Philip Rivers aired out 35 passes in a 48-27 loss to the 49ers in Week 16.
  • In both of his starts, the 44-year-old has thrown an interception.
  • Before his retirement, interceptions plagued Rivers. He coughed up at least 18 interceptions in a season four times.
  • The Jaguars have been adept at picking off passes, compiling 19 interceptions. That trails only the Bears, who lead the NFL with 21 picks.
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Make NFL Picks on PrizePicks

Chase and Barkley are two of the biggest names who will take the field for the Sunday slate of games. They both have favorable matchups that could see them pile up the stats. While they don’t carry the same name recognition, Carter and Tracy are among the other players who could thrive.

With plenty of positions and projection categories to consider, now is the time to build your NFL Lineup on PrizePicks. Just pick More or Less for at least two NFL player stat projections to build your Lineup on PrizePicks. Check out the Playbook for more NFL DFS picks and analysis all the way through the season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

Mike Barner has been covering fantasy sports since 2007. He specializes in the NBA, NFL, and MLB. He is a two-time finalist for the Fantasy Sports Writers Association Basketball Writer of the Year award and won the 2021-22 FSGA NBA Experts Champions league. In addition to PrizePicks, Mike has written for Sports Illustrated, RotoWire, SportsLine, and more.

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