The 2025 NFL regular season has arrived, and with it, a full slate of games will bless us on Sunday that we need to dig into. Need a refresher before jumping into the Week 1 games? We got you, with the NFL Week 1 stats to know.
We'll dive deep into four Week 1 games with team and player stats to bring you key insights to make your picks and predictions this week, whether you're playing fantasy football or NFL DFS on PrizePicks.
The Bengals travel to Cleveland, where they will try to buck their recent trend of slow starts; WR Drake London and the Falcons look to continue their success against the Buccaneers; and Sunday Night Football gives us a treat as MVP candidates Lamar Jackson and his Ravens takes on Josh Allen and the Bills.
Below, we'll dive into the Week 1 stats to know before you make your picks, including the top PrizePicks NFL picks to target. On PrizePicks, you can pick your players and predict More or Less on their Week 1 stats to win real money when your picks are right — all season long.
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Bengals vs. Browns: Week 1 Stats to Know
- The Bengals have started 0-2 or worse each of the last three seasons, including 0-3 last season. This included a 24-3 loss at Cleveland to start the 2023 season.
- Bengals QB Joe Burrow is 3-5 in his career against the Browns — one of only three teams he has a losing record against (min. 3 starts): 3-6 vs Baltimore Ravens, 0-3 vs. Washington Commanders.
- In those 8 games, Burrow averaged 248.8 pass yards per game with 15 passing TDs and 5 INTs.
- In WR Ja'Marr Chase’s seven career games vs. the Browns, he is averaging 5.4 receptions a game and 57.7 receiving yards per game. The 57.7 yards per game is the lowest vs. any opponent he has faced more than twice.
- Chase has only had more than 6 receptions vs. the Browns once in seven games — the same game was the only time he had more than 100 receiving yards vs. them.
- Browns QB Joe Flacco has started 11 total games over the last two seasons for both the Colts and Browns combined. In those 11 games, both teams have averaged a total of 53.1 PPG combined in those matchups.
- Browns WR Jerry Jeudy received 10+ targets in six of the final nine games of the 2024 season. However, in two games vs. the Bengals, he totaled 3 catches for 38 yards.
- The Bengals defense allowed 25.5 points per game (26th in NFL) and 384.3 yards per game (25th in NFL) in the 2024 season.
Bengals vs. Browns Picks to Target for NFL DFS
Bengals vs. Browns projections are via the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Browns WR Jerry Jeudy – 7.5 Targets
- Bengals RB Chase Brown – 68.5 Rushing Yards
- Bengals QB Joe Burrow – 1.5 Pass TDs
Buccaneers vs. Falcons: Week 1 Stats to Know
- Despite not winning the NFC South, the Falcons swept the Buccaneers in their two meetings last year, winning 36-30 and 31-26. The games averaged 61.5 points per game.
- In four games vs. the Falcons as the Buccaneers QB, Baker Mayfield is 1-3 with 9 TDs and 3 INTs, averaging 232.3 points per game.
- Buccaneers WR Mike Evans has faced the Falcons 19 times and has posted more than 100 receiving yards four times — none with Baker Mayfield as QB.
- In those three games with Mayfield, Evans has 12 catches for 152 total yards, but the Bucs will be without Bucs WR Chris Godwin.
- Falcons QB Michael Penix Jr. played the majority of his snaps in Weeks 16, 17, and 18 last season. During those three weeks, WR Drake London led the NFL in receiving yards and targets with 352 yards on 39 targets.
- In those three games, London had an average depth of target of 12.9 yards downfield.
- London had the two games with his most catches and yards of his career vs. the Buccaneers, catching 10 balls for 172 yards in Week 14 of 2023 and 12 catches for 154 yards last year in Week 5.
- Falcons RB Bijan Robinson has made three starts vs. the Buccaneers and have held him under 65 yards in all of those games.
- The Buccaneers defense allowed 97.8 rush yards per game last year, the 4th-fewest of any NFL team. In 2023, they allowed 95.3, which was 5th-fewest.
Bengals vs. Browns Picks to Target for NFL DFS
Buccaneers vs. Falcons projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Falcons WR Drake London – 73.5 Receiving Yards
- Falcons RB Bijan Robinson – 70.5 Rush Yards
- Bucs QB Baker Mayfield -– 242.5 Pass Yards
Lions vs. Packers: Week 1 Stats to Know
- Lions QB Jared Goff is 6-2 as a starter in season opening games. Meanwhile, the Lions are 5-1 vs. the Packers the last three seasons, including a perfect 3-0 at Green Bay.
- As Lions QB, Goff is 6-2 vs. the Packers, averaging 226.9 passing yards per game with 13 TDs and 4 INTs.
- In five of the eight games, Goff has thrown for 2+ TD passes.
- Lions WR Amon-Ra St. Brown has hit 100+ receiving yards in one of seven starts made vs. the Packers and in none of his past six games.
- Lions RB Jahmyr Gibbs has 16 receptions in four games vs. the Packers.
- Packers QB Jordan Love has one win in four starts vs. the Lions, with 6 passing TDs and 5 Ints.
- Including playoffs, the Lions have scored 30+ points in their last six games, and 13 of their last 20 games.
- Lions RB David Montgomery has 5 TDs in eight career games vs. the Packers.
Lions at Packers Picks to Target
Lions vs. Packers projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Lions RB Jahmyr Gibbs – 3 Receptions
- Packers QB Jordan Love – 0.5 INTs
- Lions QB Jared Goff – 237.5 Pass Yards
Ravens vs. Bills: Week 1 Stats to Know
- Last year, the Ravens offense was No. 1 in EPA/play and dropback EPA.
- Bills QB Josh Allen has faced the Ravens five times in his career as a starter, including the postseason. The most yards he has thrown for in those three games is 213, with 3 total pass TDs and three rushing TDs.
- In those same five games, Ravens QB Lamar Jackson has 9 total TDs, with just one game over 220 pass yards.
- Ravens RB Derrick Henry has rushed for 84+ yards in three of his last four games vs. the Bills, going for 199 in the Week 4 matchup last season.
- Including playoffs, the Ravens have scored 25+ points in their last six games and in 14 of their last 17 games.
- The Bills have scored 25+ points in their last three games and in 12 of the last 14.
Ravens vs. Bills Picks to Target for NFL DFS
Ravens vs. Bills projections are from the PrizePicks real money NFL game — pick players, predict More or Less on their stats, and win cash when you're right.
- Bills QB Josh Allen – 0.5 Rush+Rec TDTDs
- Ravens QB Lamar Jackson – 229.5 Pass Yards
- Ravens RB Derrick Henry - 83.5 Rush Yards
Pick More or Less on NFL Week 1 Stats
The Buccaneers vs. Falcons, Browns vs. Bengals, and the Lions vs,. Packers kickoff the NFL season with key divisional matchups. Meanwhile, Ravens QB Lamar Jackson and Bills QB Josh Allen look to give their teams a leg up early in the AFC race.
We hope these Week 1 stats to know can help you make your picks and predictions on PrizePicks real money NFL game.
Simply pick your players, predict More or Less on their Week 1 stats, and win cash when you're right. It's the simplest way to play NFL DFS, all season long.
