The Big Monday showdown in Chapel Hill showcases a pair of squads seeking their tenth ACC victory.
The Louisville Cardinals (20-7) play three of their final four regular season games on the road, coming off an 87-70 home victory over Georgia Tech on Saturday.
The North Carolina Tar Heels (21-6) start a three-game stretch at the Dean Dome following a 77-64 road triumph over Syracuse.
Let’s look at the Louisville vs. North Carolina prediction, spread, and picks for Monday’s massive tilt at Dean E. Smith Center in Chapel Hill, tipping off at 7:00 p.m. ET on ESPN.
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Louisville vs. North Carolina Prediction, Spread, Picks
The Tar Heels captured five consecutive matchups from 2021 through 2024. Louisville ended that hex with an 83-70 home victory last January, 83-70 as 1.5-point favorites.
The teams combined to shoot 10-of-42 from 3-point range, while the Cardinals won in spite of missing 14 free throws.
Louisville last won in Chapel Hill in 2019, stunning UNC as 11-point underdogs, 83-62.
Louisville vs. North Carolina Over/Under, Spread
The Cardinals enter this matchup as 2.5-point favorites, returning a 1.66x payout on PrizePicks Team Picks if they win outright.
The Tar Heels are home underdogs with a 2.12x payout if they win, via PrizePicks Team Picks.
- Spread: Louisville -2.5
- Over/Under: 161.5
- Game Winner Payout: Louisville 1.66x | North Carolina 2.12x
(Team Picks data is live as of writing and is subject to change)
Louisville vs. North Carolina Numbers to Know
Here are some facts and figures to get you set for Louisville vs. North Carolina tonight, including insights on our Louisville vs. North Carolina prediction.
- The Cardinals are 3-6 against the spread (ATS) in the last nine games. Louisville failed to cover in the win against Georgia Tech and lost as a road favorite at SMU.
- In the past five road conference games, the Cardinals covered the spread once, coming in a 100-59 rout of Pittsburgh on January 17.
- UNC has failed to cash the number in consecutive games this month. The Tar Heels covered three straight to close out January against Notre Dame (91-69), Virginia (85-80), and Georgia Tech (91-75).
- North Carolina hit eight consecutive overs before finishing under the total in four of the last five games.
- Louisville ranks in the top four in ACC play in 3-point shooting (35.9%), 2-point shooting (58.4%), and free throw shooting (78.5%).
- North Carolina sits last in conference action defending the 3-point shot, allowing opponents to convert 39.1% of its attempts.
- The Tar Heels held Syracuse to 3-of-17 shooting from downtown on Saturday, their best defensive performance in ACC play.
- Both Louisville and North Carolina own 9-5 conference marks, looking to tie Clemson for fourth place with a victory.
- North Carolina freshman star Caleb Wilson (19.8 PPG) remains sidelined with a left hand injury. The Tar Heels are 2-1 since his injury.
Louisville vs. North Carolina CBB Player Picks
Here are three top Louisville vs. North Carolina picks to target on Monday. Key PrizePicks player projections are headlined by three players: Louisville G Mikel Brown, Jr., North Carolina C Henri Veesaar, and Cardinals G Ryan Conwell.
Louisville G Mikel Brown Jr. vs. North Carolina Projection: 21.5 Points
- The freshman torched NC State for 45 points on February 9, hitting 10-of-16 shots from deep.
- In the last four games, Brown drilled 21-of-36 3-point tries for a scorching 58.3%.
- The Orlando native topped the 29-point mark in three straight outings before scoring 19 points in Saturday’s win over Georgia Tech.
- Prior to his 29-point output against SMU on February 17, Brown combined for 19 points in two road games at Wake Forest and Duke.
North Carolina C Henri Veesaar vs. Louisville Projection: 27.5 Pts+Rebs
- Veesaar returned from a two-game absence, scoring 19 points and grabbing 3 rebounds against Syracuse.
- In the past three games, the junior failed to reach this projection, averaging 14.3 PPG and 6.6 rebounds per game.
- Veesaar hasn’t attempted a free throw in the last three contests and tried seven foul shots in the past six games.
- The Estonia native pulled down at least 10 rebounds in five of the previous six home contests. In the outlier, he snatched 9 boards against Wake Forest on January 10.
Louisville G Ryan Conwell vs. North Carolina Projection: 17.5 Points
- The senior is averaging a career-high 18.3 PPG after scoring 16.5 PPG at Xavier last season.
- Conwell finished with less than 15 points in six of the last seven games.
- Since January 24, the Indianapolis native topped the 20-point mark once, posting 31 points in a 118-77 rout of NC State.
- Conwell knocked down 5-of-6 attempts from deep in that 31-point performance, but hit 5-of-23 3-point attempts in the past three games.
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Make Picks Louisville vs. North Carolina CBB on PrizePicks
A huge game for ACC tournament seeding takes place in Chapel Hill tonight with Louisville and North Carolina shooting for fourth place.
There’s never been a better time to add to the excitement of every CBB moment than with PrizePicks.
There are hundreds of player stat projections on the CBB board for every game; just pick at least two player stat projections to build your Lineup on PrizePicks. Or, make your picks on winners, spreads, and over/unders on Team Picks, now available in 34 states!
Check out the Playbook throughout the season for more CBB picks, predictions, and news every day.





