Three interconference matchups populate Friday night’s NBA slate, and perhaps the most intriguing of the bunch takes place when the New York Knicks meet up with the Denver Nuggets.
The 9:00 p.m. bout at Ball Arena sees a battle-tested Nuggets team clash with a hungry Knicks squad. With the NBA playoff picture coming into focus, this matchup is critical for both sides.
Below, we’ll break down our Knicks vs. Nuggets prediction and picks for Friday night’s game. Make your NBA picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Knicks vs. Nuggets Prediction, Spread, Over/Under
Following a 51-31 campaign but another failed attempt to reach the NBA Finals, the Knicks let head coach Tom Thibodeau go and ushered in the Mike Brown era. Thus far, New York is 40-23, good for the No. 3 seed in the Eastern Conference.
Denver also let its head coach go in 2025, albeit late in the regular season. Out is Michael Malone, and in is David Adelman. The Nuggets, marred by injuries all year, still sit pretty at 49-24. That’s good for the fifth seed in a tight-knit Western Conference.
Friday is the 103rd all-time regular-season clash between these two clubs. It’s a close series, with the Nuggets owning a 52-50 lead, although the Knicks have won three straight.
Knicks vs. Nuggets Spread, Over/Under
The Knicks enter Friday’s game as 1.5-point road favorites, returning a 1.78x payout on PrizePicks Team Picks if they win outright.
The Nuggets are home underdogs with a 2x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 34 states.
- Spread: New York Knicks -1.5
- Over/Under: 229.5
- Game Winner Payout: Knicks 1.78x | Nuggets 2x
Team Picks data is live at the time of writing and is subject to change.
Knicks vs. Nuggets Injury Report
Let’s dive into the full Knicks vs. Nuggets injury report for Friday, via NBA.com.
New York Knicks Injury Report
- F-G Josh Hart (back): Questionable
Denver Nuggets Injury Report
- PF Aaron Gordon (hamstring): Questionable
- F Cameron Johnson (ankle): Questionable
- SF Spencer Jones (shoulder): Questionable
- F-G Peyton Watson (hamstring): OUT
Knicks vs. Nuggets Prediction on Spread
Here are the key stats to know before locking in your Knicks vs. Nuggets prediction on spread for Friday, March 6 on PrizePicks.
- These two teams perform remarkably similarly against the spread. Denver is 35-28-1 ATS, whereas the Knicks are right behind them at 35-29.
- New York’s offense produces a healthy 117.0 PPG, ranking 10th, also occupying the No. 8 slot for effective field goal percentage (55.3).
- Defensively, the Knicks allow the sixth-lowest shooting percentage (45.7) and surrender the fourth-fewest points in the paint each night (43.9).
- The Nuggets’ offense puts up more PPG (120.4) than any NBA team. Denver also paces the field in eFG% at 57.2.
- Adelman’s crew does show a bit of weakness on defense, ranking 19th in scoring (116.0 PPG) and 21st inside the arc (55.3%).
Knicks vs. Nuggets Picks for PrizePicks Today: 3/6/26
Here are three top Knicks vs. Nuggets picks to target for Friday, March 6 on PrizePicks. Player stat projections via PrizePicks are headlined by PG Jalen Brunson, PG Jamal Murray, and C Nikola Jokic.
Knicks PG Jalen Brunson vs. Nuggets Projection: 33.5 Pts + Asts
- Brunson averages 32.8 combined points and assists per game. In 15 outings since the start of February, that number is 30.9.
- The eighth-year PG’s 58.4 true shooting percentage is his lowest mark since 2021-22, when he was with the Dallas Mavericks.
- Although Brunson’s usage rate is 30.5%, his 29.8% assist clip marks the first year below 30% since 2022-23.
- The Knicks’ franchise player averages just 1.4 potential assists per minute on-ball, per NBARAPM.
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Nuggets PG Jamal Murray vs. Knicks Projection: 30.5 Pts + Asts
- Murray’s career campaign rolls on, seeing him post a combined average of 33 points and assists.
- The 10th-year man is canning a career-best 48.4% of his shots from the field and 43.2% of attempts from deep.
- After seeing his on-ball workload drop to 29% last season, Murray is up to a personal record of 38%.
- Murray’s 18.2 potential assists per 100 possessions puts him in the 99th percentile, according to databallr.
Nuggets C Nikola Jokic vs. Knicks Projection: 48.5 Pts + Rebs + Asts
- On the year, Jokic averages 51.6 points, rebounds, and assists. Since his return to the lineup on January 30, that benchmark is down to 47.8.
- In 11 games in February, the three-time MVP shot just 46.6% on field goals and an ugly 31.1% on 3-pointers.
- New York cedes the sixth-fewest rebounds each night to opponents (50.9), including being the third-stingiest on the offensive boards (10.2).
- In that same post-injury, Jokic’s 44.4% assist rate is well below his season average of 48.7%.
Make Knicks vs. Nuggets Picks on PrizePicks
Knicks vs. Nuggets picks aren’t the only avenue hoops fans have to getting in on the daily NBA action.
You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states.
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