The New York Knicks and Philadelphia 76ers meet in a Saturday afternoon national TV game (3:00 p.m. ET on ABC). This is the 479th regular-season showdown between the longtime rivals, who have also squared off 39 times over 10 postseason series.
The Knicks sit in third place in the Eastern Conference but have lost four out of five and nine of their last 12. The Sixers are in fifth place with wins in two of the last three contests.
Below, we’ll break down our Knicks vs. 76ers prediction and picks for Saturday’s game. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Knicks vs. 76ers Prediction, Spread, Over/Under
The Knicks and 76ers clash for the third time this season. Philly took the first two games by a combined three points. It’s a turnaround from last season, when New York swept through the four-game season series.
Knicks vs. 76ers Over/Under, Spread
The Knicks enter this Saturday Eastern Conference game as 1.5-point favorites, returning a 1.81x payout on PrizePicks Team Picks if they win.
The 76ers are the small underdogs with a 1.88x payout if they win, via PrizePicks Team Picks.
- Spread: New York Knicks -1.5
- Over/Under: 228.5
- Game Winner Payout: Knicks 1.81x | 76ers 1.88x
Team Picks data is live at the time of writing and is subject to change.
Knicks vs. 76ers Prediction on Spread
are you accepting or denying? pic.twitter.com/05U5c89rmn
— Philadelphia 76ers (@sixers) January 23, 2026
Saturday marks the 11th time in the last 12 games the Knicks have been the favorite. Here are some stats to get you ready for Knicks vs. 76ers.
- The Knicks are 22-23 against the spread. They covered and won on Wednesday night vs. the Brooklyn Nets, ending a streak of not covering in four straight games.
- New York is 20-19 ATS as a favorite but just 4-11 ATS as a road favorite, the most non-covers of any team.
- Twenty-four of the Knicks’ 45 games have gone over the projected total, the sixth-highest percentage of any NBA team. However, each of the last three and four of their last five games finished below the listed mark.
- The Knicks are eighth in the NBA in scoring at 117.9 PPG, third in 3-point percentage (37.7), and third in offensive rating at 119.1.
- The 76ers have been one of the better ATS teams, covering in 25 of 43 games (58.1%). That’s the second-highest cover clip behind the Phoenix Suns.
- Philly is 10-7 ATS as an underdog, including a 5-4 figure at home.
- Similar to the Knicks, the 76ers have played more games to the tune of the over (23 of the 43 matchups).
- The Sixers’ offense has struggled shooting, as they are 26th in field goal efficiency (45.6%) and 25th in effective field goal percentage (52.8). On the defensive side, they are 11th in defensive rating at 113.3.
Knicks vs. 76ers Injury Report
Let’s dive into the full Knicks vs. 76ers injury report for Saturday, via NBA.com
Knicks Injury Report
- C Karl-Anthony Towns (back): Questionable
76ers Injury Report
- C Joel Embiid (ankle): Probable
- F Paul George (knee): Probable
Knicks vs. 76ers Picks for PrizePicks Today: Saturday, January 24
Here are two Knicks vs. 76ers picks to target for Saturday, January 24 on PrizePicks. Player stat projections via PrizePicks are headlined by Knicks PG Jalen Brunson and 76ers PG Tyrese Maxey.
Knicks PG Jalen Brunson Projection vs. 76ers: 37.5 Pts + Rebs + Asts
This game showed why Jalen Brunson was named the captain. They got smoked by a bad Dallas team and he held a players-only meeting to wake up the guys.
— Dylan Backer (@DylanBackerESM) January 22, 2026
They responded with the largest win in franchise history. Keep this energy the rest of the way. pic.twitter.com/UyqeiwK68N
- Brunson has failed to reach his player points + rebounds + assists projection in 22 of 40 games, including six of the last seven.
- The veteran PG has scored 20+ in 20 consecutive games in which he didn't leave with an injury.
- After recording 7+ assists eight times over a span of 10 games, the Villanova product has only done so twice in his last nine.
- In two prior games this year vs. the 76ers, Brunson averaged 26.5 points, 6.5 assists, and 5.0 rebounds.
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76ers PG Tyrese Maxey Projection vs. Knicks: 5.5 Assists
Tyrese Maxey of the @sixers has tallied 142 made threes and 83 steals in his 40 games this season.
— OptaSTATS (@OptaSTATS) January 22, 2026
The only other player in NBA history to reach those two marks in his first 40 games of a season was Stephen Curry in 2015-16, when he became the first unanimous NBA MVP. pic.twitter.com/yvKpDh61Wd
- Maxey has recorded 6+ assists in 28 of 41 games, including each of the last four.
- Over those four outings, Maxey has stockpiled 34 assists, good for an average of 8.5 per game.
- The Kentucky product averages 6.8 assists on the year, 20th-best in the NBA and the most on the 76ers.
- Maxey’s usage percentage of 28.6% ranks 25th in the league and 18th among guards.
Make Knicks vs. 76ers Picks on PrizePicks
Can the Knicks turn Thursday’s blowout of the Nets into a winning streak by slowing the 76ers, or will Philadelphia continue climbing up the Eastern Conference standings?
You can make your Knicks vs. 76ers picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.
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