Big Ten hoops action is back on Friday night, with the Indiana Hoosiers hitting the road to square off against the Purdue Boilermakers at Mackey Arena in West Lafayette, IN.
The nighttime bout (8:00 p.m. ET on FOX) sees the No. 7-ranked Boilermakers host a Hoosiers squad that’s looking to further bolster its case for the NCAA Tournament.
Below, we’ll break down our Indiana vs. Purdue prediction and picks for Friday’s game. Make your college basketball picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Indiana vs. Purdue Prediction, Spread, Over/Under
Following consecutive 19-win campaigns, Indiana is just two victories away from matching that total in year one with Darian DeVries as head coach. They’re 8-7 in conference play and have split their last four contests.
Purdue, meanwhile, has rounded back into form after an underwhelming 24-12 season under Matt Painter. This year, the Boilermakers are 21-5, including an 11-4 conference record.
Friday night marks the 142nd clash between Indiana and Purdue since 1949, with the Boilermakers owning a narrow 71-70 series advantage. That includes an average win margin of 1.1 points.
Indiana vs. Purdue Spread, Over/Under
Indiana enters Friday’s game as 10.5-point road underdogs, returning a 5.26x payout on PrizePicks Team Picks if they win outright.
Purdue is a home favorite with a 1.12x payout if they win, via PrizePicks Team Picks.
- Spread: Purdue Boilermakers -10.5
- Over/Under: 148.5
- Game Winner Payout: Hoosiers 5.26x | Boilermakers 1.12x
Team Picks data is live at the time of writing and is subject to change.
Indiana vs. Purdue Prediction on Spread
Here are some stats to know to help you make your Indiana vs. Purdue prediction on Friday, February 20.
- Neither team fares particularly well in its home/away split against the spread. Purdue is just 4-9 ATS as home favorites, with Indiana being 2-3 ATS as road underdogs.
- Indiana’s offense sits 66th in per-game scoring at 80.3 PPG but makes shots to the tune of the 29th-best effective field goal percentage (55.9).
- Defensively, the Hoosiers hold opponents to the 26th-lowest eFG% (47.1) and are top-50 against both 3-pointers (30.9%, 37th) and 2-pointers (47.6%, 47th).
- Purdue’s offense keeps the ball moving and takes care of it, ranking second in average assists (19.5) and leading the nation in assist-to-turnover ratio (2.126).
- On the other end of the court, the Boilermakers are 100th in opponent shooting efficiency (1.068) and 115th in made field goals ceded (25.1 per game).
Indiana vs. Purdue Picks for PrizePicks Today: 2/20/26
Here are three top Indiana vs. Purdue picks to target for Friday, February 20 on PrizePicks. Player stat projections via PrizePicks are headlined by G Lamar Wilkerson, G Braden Smith, and F Trey Kaufman-Renn.
Indiana G Lamar Wilkerson vs. Purdue Projection: 28.5 Pts + Rebs + Asts
- In his senior campaign, Wilkerson averages a combined 27.4 points, rebounds, and assists.
- Wilkerson’s impressive 61.5 true shooting percentage and 22.6 PER on the season include sparkling 62.9 and 27.0 marks during Big Ten play.
- The Sam Houston State transfer has held a rebounding percentage between 6.6 and 6.8 in three straight years.
- Despite his usage rate being a career-high 29.3%, Wilkerson’s personal best assist clip (16.5%) comes with a 7.8% turnover share that’s a new low.
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Purdue G Braden Smith vs. Indiana Projection: 29.5 Pts + Rebs + Asts
- Twenty-six games into his fourth year with the Boilermakers, Smith produces 27.5 points, rebounds, and assists each night. In conference play, that figure rises to 29.0.
- In his last dozen outings, Smith is making 50.3% of his field goals, 43.1% of his 3-point tries, and 86.1% of his free throws.
- Indiana ranks 270th with a 74.4% opponent defensive rebound rate allowed.
- After leading the nation with a 44.1% assist rate in 2024-25, Smith maintains a video game-like 43.8% mark in 2025-26.
Purdue F Trey Kaufman-Renn vs. Indiana Projection: 25.5 Pts + Rebs
- Another Purdue senior, Kaufman-Renn pours in 22.1 combined points and rebounds nightly. Since the start of Big Ten contests, that number’s dropped to 21.3.
- Kaufman-Renn thrived a year ago, leading the Big Ten with a 27.0 PER and a 31.8% usage rate. This year, those benchmarks have declined to 22.5 and 23.7, respectively.
- One thing that’s improved is Kaufman-Renn’s rebounding. He tops all Big Ten players in both defensive rebounding rate (24.6%) and total rebounding clip (19.8%).
- Per Bart Torvik, among 21 Big Ten athletes capable of matching his minutes share and usage, Kaufman-Renn ranks 11th in adjusted points over replacement.
Make Indiana vs. #7 Purdue Picks on PrizePicks
Indiana vs. Purdue Big Ten picks are just one of many ways hoops fans can get in on the daily college basketball action.
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