Week 13 of the NFL campaign ends with a clash between teams whose seasons have gone in opposite directions. The 2-10 Giants hit the road to face the 10-2 Patriots on the Monday Night Football stage.
This Monday matchup (8:15 p.m. ET on ESPN) is one of streaks. The Giants come into the week having dropped six straight contests, whereas the Patriots have won nine in a row since starting 1-2.
Below, we’ll break down some Giants vs. Patriots MNF picks as Week 13 of the season comes to a close. Use PrizePicks’ NFL game for player projections on QB Jaxson Dart and others.
Giants vs. Patriots MNF Picks Tonight: Week 13
Monday Night Football marks the 15th all-time meeting between the Giants and Patriots. With everything knotted up at 7-7, including a pair of Super Bowls, it’s been a tightly-contested series.
The Giants enter Monday’s game as 7.5-point road underdogs, returning a 3.7x payout on PrizePicks Team Picks if they win outright.
The Patriots are home favorites with a 1.25x payout if they win, via PrizePicks Team Picks.
- Spread: New England Patriots -7.5
- Total: 46.5
- Game Winner Payout: Giants 3.7x | Patriots 1.25x
Let’s take a closer look at the Giants vs. Patriots matchup, including top Monday Night Football PrizePicks player picks and projections for QB Jaxson Dart, QB Drake Maye, and WR Stefon Diggs.
Giants QB Jaxson Dart vs. Patriots Projection: 237.5 Pass + Rush Yards
- In seven starts, Dart averages 247.7 combined passing and rushing yards. When removing his debut under center, that number spikes to 261.5.
- Per NFL Pro, Dart has completed 77.6% of quick pass tries, eighth in the NFL. The Patriots allow the 11th-highest completion mark (74.3%) on such throws.
- Dart reached 50+ rushing yards in five of seven games from Weeks 4-10, leading all QBs in attempts (55), ground yardage (317), and rushing TDs (7).
- It’s worth monitoring how often Dart runs in his return from a concussion. He logged 5+ rush attempts in each 2025 start, including two games in double digits, before the injury.
Patriots QB Drake Maye vs. Giants Projection: 245.5 Pass Yards
- Maye averages 260.8 passing yards per game, including a 277.2 mark in his last five contests.
- According to SumerSports, Maye’s 99.02 pass EPA trails only Packers QB Jordan Love (100.91) this year.
- Prior to firing defensive coordinator Shane Bowen, the Giants ranked third in man coverage usage (32.6%, per Sharp Football Analysis). Maye’s 9.2 yards per attempt against man ranks second in the league.
- New York’s defense sits 22nd in EPA/dropback, 23rd in passing yards allowed, and 23rd in sack rate.
Patriots WR Stefon Diggs vs. Giants Projection: 47.5 Rec Yards
- Diggs has gone over the 45-yard receiving mark in half of his 12 games this year.
- Out of 67 WRs with 250+ opportunities, the four-time Pro Bowler ranks fifth at 2.49 yards per route run, via SumerSports.
- Diggs’ 81.3% catch rate and 65.3% success rate are both career-high marks for his 11-year NFL tenure.
- The Giants have yielded more receiving yards to WRs (2,002) than all but four teams.
- Per NFL Pro, Diggs has the NFL’s highest catch rate (90.9%) on outside-the-numbers targets. New York’s defense allows the 10th-highest yards per target (7.4) on those throws.
Make Giants vs. Patriots Picks on PrizePicks
Week 13 of the season may conclude with New York and New England going head-to-head, but Giants vs. Patriots picks aren’t your only avenue to rewards. With PrizePicks’ real-money NFL game, you can cash in on the action.
Doing so is simple. Just pick your players, predict More or Less for their projected stats, and win rewards if you’re right.
Keep it here with the Playbook for continued football coverage.
