Colts vs. Jaguars Prediction, Picks: Daniel Jones-Trevor Lawrence Tussle

Colts QB Daniel Jones throws a pass in an NFL game.
AP Photo/Darron Cummings

The Colts and Jaguars, tied atop the AFC South, square off in the first of their two annual division meetings,with the rematch in three weeks in Jacksonville. The Jags have won three of the last four meetings between the two teams.

The Colts and Jaguars Week 14 game kicks off Sunday at 1:00 p.m. ET on CBS.

Below, we'll break down our Colts-Jaguars prediction and Sunday picks for Week 14, including the top player picks on PrizePicks real money NFL game, among them Colts QB Daniel Jones and RB Jonathan Taylor and Jaguars QB Trevor Lawrence.

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Colts vs. Jaguars Over/Under Picks, Spread on PrizePicks 

The Colts had a 2.5-game lead in the AFC South after Week 8 of the season, but after losing three of the last four weeks, the division is now tied. 

Indy enters the Sunday Week 14 game as 2.5-point road favorites, returning a 1.72x payout on PrizePicks Team Picks if they win.

The Jaguars are home underdogs with a 2x payout if they win, via PrizePicks Team Picks.

Spread: Indianapolis Colts -2.5

Total: 48.5a

Game Winner Payout: Colts 1.72x | Jaguars 2x


Colts vs. Jaguars Over/Under: 48.5 

The total of 48.5 is the third-highest total of the Week 14 slate, behind Thursday’s Cowboys-Lions (53.5) and Sunday’s BIlls-Bengals (53.5) games. 

  • Overall, Indy’s 12 games have been six unders and six overs, but three of the last four have gone under. 
  • The listed total of 53.5 would be the highest total of any Colts game this season and only the second one over 50 this season (Week 9 vs. Pittsburgh was 52).  
  • The Colts lead the NFL in scoring, averaging 29.8 PPG. They also top the league at 6.26 yards per play and 5.1 yards per rush. 
  • On the defensive side, the Colts are ninth in the NFL, allowing 20.8 PPG. 
  • Jacksonville has also played six unders and six overs this season, with three of the last five Jaguars games going over. 
  • The 53.5 total is the first Jaguars game this season over 50. Their Week 2 game vs. the Bengals was 49.5 and ended 31-27. 
  • The Jaguars average 24.3 points per game on offense (11th) and allow 21.1 points per game (12th).
  • According to DVOA, the Colts have the second-best offense and the Jaguars 21st. 

Colts vs. Jaguars Prediction, Picks

Here are three Colts vs. Jaguars player picks for Week 14 for PrizePicks real money NFL game, including Colts QB Daniel Jones and RB Jonathan Taylor and Jaguars QB Trevor Lawrence..

Pick More or Less on these projections on PrizePicks — plus thousands more —to win real money this NFL season.

Colts QB Daniel Jones Projection vs. Jaguars: 233.5 Pass Yards

  • Colts QB Daniel Jones has hit more than his player projection in eight of 12 games this season, but not in the last two games. 
  • The listed projection of 233.5 is the fourth-highest posted passing projection of the season for Jones. He has had more than his projection in each of the other three highest ones. 
  • In seven of Jones’ 12 games this season, he has 250+ yards passing, including four straight from Weeks 7-10. Since the Colts bye week, Jones has a high of 201 passing yards.  
  • After throwing for 1 TD in each of his first four games of the season, Jones has 2+ TD passes in six of his last eight.   

Colts RB Jonathan Taylor Projection vs. Jaguars: 93.5 Rush Yards

  • Colts RB Jonathan Taylor has hit more on his rushing prop in six of 12 games this season. 
  • The listed player projection of 93.5 rushing yards is the third-highest of the season for Taylor. The projection was listed at 99.5 in Week 8 vs. Tennessee (153 yards rushing) and 97.5 in Week 9 vs. Pittsburgh (45 rush yards)
  • Taylor has five 100+ yard games this season, second-most in the NFL behind James Cook. 
  • The Colts lead back has rushed for an NFL-high 1,282 yards on the season and also leads the league with 15 rushing TDs. 

Jaguars QB Trevor Lawrence Projection vs. Colts: 222.5 Pass Yards

  • Jaguars QB Trevor Lawrence has hit more on his passing prop in six of 12 games this season, including each of the last two games.
  • The 222.5 listed player passing yards projection marks the fifth straight game in which it was lower than 230 passing yards. 
  • The Clemson product has failed to pass for 225+ yards in seven of his 12 starts this season.  
  • Per PFF, Lawrence ranks 11th in ADot and 16th in time to throw among all QBs.     
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Make Week 14 Football Picks on PrizePicks

Will the Colts-Jaguars game be the high-flying affair that the over/under implies? Or will either of the defenses step up for a lower scoring game? The Colts and Jaguars meet on Sunday at 1:00 p.m. ET on CBS.

As the NFL season enters its 14th week, there's no better place to get real money action with your NFL predictions than on PrizePicks.

There is a wide variety of player stat projections on the NFL board, so you can make predictions on whatever you'd like — from yards to field goals. Just pick at least two players and pick More or Less on their stats to build your Lineup on PrizePicks.

Check out the Playbook throughout the NFL season for more NFL predictions for your PrizePicks and NFL DFS Lineups.


Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

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about the author

David Bearman spent 18 years with ESPN in their Stats & Information Department and overseeing their betting content. From 2023-25, he served as Chief Content Officer of Pro Football Network, overseeing all content, including coverage of Super Bowls 58 and 59. He is also the Founder of Betting with Bearman, a 3x a week betting newsletter and weekly podcast on Bleav Podcast Network.

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