The San Antonio Spurs (45-17) continue their homestand when they take on the Los Angeles Clippers (30-31) on Friday evening.
The two teams have yet to play each other this season, but the Clippers came away with a 122-117 win in their most recent clash last April. Tip-off for Friday’s showdown is scheduled for 9:30 p.m. ET on ESPN.
Below, we'll break down our Clippers vs. Spurs prediction and picks for Friday night's contest. Make your NBA picks on PrizePicks and earn real money if you’re right, including on game winners, spreads, and totals.
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Clippers vs. Spurs Prediction, Spread, Over/Under
The Spurs are nipping at the heels of the Oklahoma City Thunder for the top spot in the Western Conference, trailing by just three games entering Friday. San Antonio has won 13 of its last 14 games and took down the Eastern Conference-leading Detroit Pistons, 121-106, on Thursday.
Spurs C Victor Wembanyama had a monster game to the tune of 38 points on 12-of-24 shooting, along with 16 rebounds and five blocks. On the flip side, Wembanyama has experienced his own offensive struggles, shooting just 44.9% from the field over the past eight games since the All-Star break.
Meanwhile, the Clippers are in the midst of a rebuilding year. While Los Angeles is currently in contention for a play-in tournament spot, the franchise moved PG James Harden and C Ivica Zubac at the NBA trade deadline.
Following the break, F Kawhi Leonard has played some very inspired basketball. Over the past six games, he's averaged 27.7 PPG and shot 35.0% from deep.
Clippers vs. Spurs Over/Under, Spread
The Spurs are 6.5-point home favorites, returning a 1.31x payout on PrizePicks Team Picks if they win outright.
The Clippers are road underdogs and return a 3.33x payout if they win outright, per PrizePicks Team Picks, where you can earn money with your picks in 34 states.
- Spread: San Antonio Spurs -6.5
- Over/Under: 223.5
- Game Winner Payout: Clippers 3.33x | Spurs 1.31x
Team Picks data is live as of writing and is subject to change.
Clippers vs. Spurs Injury Report
Let’s dive into the full Clippers vs. Spurs injury report for Friday, via NBA.com.
Los Angeles Clippers Injury Report
- PF John Collins (neck): OUT
- PG Darius Garland (toe): OUT
San Antonio Spurs Injury Report
- F Harrison Barnes (ankle): OUT
- SF Julian Champagnie (knee): Questionable
- C Mason Plumlee (conditioning): OUT
Clippers vs. Spurs Prediction on Spread
Here are the key stats to know before locking in your Clippers vs. Spurs prediction on the spread for Friday, March 6, on PrizePicks.
- The Spurs have a 14-11-1 against-the-spread record as a home favorite, producing a 56.0% cover rate.
- The Clippers are 9-1 ATS in their last 10 games.
- Los Angeles allows its opponents to put up the seventh-fewest shot attempts per game (87.5) in the NBA.
- San Antonio ranks third in rebounds per game (46.5).
- The Spurs have recorded 16.4 fastbreak points per contest, ranking ninth.
Clippers vs. Spurs Picks for PrizePicks Today: 3/6/26
Here are two of the top Clippers vs. Spurs picks to consider for Friday, March 6. Today's PrizePicks NBA player projections feature C Victor Wembanyama and G-F Bennedict Mathurin.
Spurs C Victor Wembanyama vs. Clippers Projection: 38.5 Pts + Rebs + Asts
- Wembanyama has averaged 36.3 points, rebounds, and assists since the break.
- The Spurs' star big man has tallied at least 39 combined points, rebounds, and assists in four of his last eight games.
- Per NBA Advanced Stats, Wembanyama pulls down 37.1% of his contested rebound opportunities.
- Wembanyama has registered at least 11 boards in five of his previous eight contests.
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Clippers G-F Bennedict Mathurin vs. Spurs Projection: 23.5 Pts + Rebs
- Mathurin has averaged 26.8 points and rebounds since being acquired via trade from the Indiana Pacers.
- The former Arizona Wildcat has scored 20+ points in four of his eight games during that span.
- Mathurin has averaged 6.3 rebounds per contest since landing with the Clippers.
- Per databallr, Mathurin records 9.8 creation true shot attempts per 100 possessions.
Make Clippers vs. Spurs Picks on PrizePicks
The Spurs continue to enjoy some home cooking as they welcome the Clippers to Frost Bank Arena. San Antonio aims to keep its sensational play alive, while Los Angeles looks to extend its winning streak to four consecutive games.
You can make your Clippers vs. Spurs picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states.
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