For the second time this month, the San Francisco 49ers and Seattle Seahawks go head-to-head on the gridiron. After Week 18’s rumble for the NFC West crown and No. 1 overall seed, this weekend’s matchup raises the stakes even higher.
This time around, it’s the Divisional Round of the playoffs. Star players could swing outcomes, and both sides possess plenty of talent. 49ers, RB Christian McCaffrey might be the player to watch as Saturday’s game (8:00 p.m. ET on FOX) approaches.
Below, we’ll expand on some Christian McCaffrey stats and a pick vs. the Seahawks in the Divisional Round. Use PrizePicks and PrizePicks Team Picks to make predictions on player projections and futures, over/unders, game winners, and spreads — now available in 30 states.
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Christian McCaffrey Stats, Pick for Divisional Round vs. Seahawks
Below are some Christian McCaffrey projections to monitor against Seattle. Use PrizePicks to make predictions on other Divisional Round player projections as well.
49ers RB Christian McCaffrey Projection vs. Seahawks: 114.5 Rush + Rec Yards
- McCaffrey produced just 29 rushing yards in Week 18, but he hauled in 6 passes. On Wild Card Weekend vs. a tough Philadelphia Eagles defense, he amassed exactly 114 scrimmage yards.
- In eight career playoff games, McCaffrey averages 118.7 combined rushing and receiving yards. He has 11 TDs in that span.
- According to StatRankings, the former Offensive Player of the Year is the only halfback with a touch share of over 40%.
- Over the last eight seasons, only 2024 Bijan Robinson and 2020 Derrick Henry forced more missed tackles than McCaffrey’s 113 (NFL Pro).
- Per SumerSports, CMC’s 23.41% target share led all RBs by more than 3%. Among players with 100+ carries, his 849 yards after contact were sixth.
- McCaffrey’s 1.80 yards per route run is his highest figure since 2021 (2.91), via Pro Football Focus.
- Seattle’s defense has allowed the third-fewest rushing yards (1,156) but the sixth-most receiving yards (640) to the RB position.
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More Christian McCaffrey Projections vs. Seahawks in Divisional Round
McCaffrey has many other Saturday Divisional Round projections for 49ers vs. Seahawks to pick from, via PrizePicks.
- 53.5 Rush Yards
- 16.5 Rush Attempts
- 11.5 Yards on Longest Rush
- 53.5 Receiving Yards
- 6.5 Receptions
- 8.5 Receiving Targets
- And More
Make 49ers vs. Seahawks Picks on PrizePicks
With two NFC West foes battling on the playoff stage, Christian McCaffrey picks aren’t the only avenues to finding real-money action with the Divisional Round.
Make your NFL playoff picks on PrizePicks and PrizePicks Team Picks. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.
Keep it locked in here with the Playbook for continued NFL picks, predictions, and news.




