A matchup between two of the best teams in the NBA takes center stage tonight when the Boston Celtics (43-21) march into the Frost Bank Center to take on the San Antonio Spurs (47-17).
This is the second and final matchup of the season between these two teams, with Boston looking to even the score after dropping the first game at home 100-95.
Celtics vs. Spurs tips off at 8:00 p.m. ET on Thursday from San Antonio, TX, live on NBC and Peacock.
Below, we’ll break down our Celtics vs. Spurs prediction and Tuesday NBA picks for PrizePicks. Use PrizePicks NBA to make picks on player projections and win real money if you’re right.
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Celtics vs. Spurs Prediction, Spread, Over/Under
Don’t look now, but the Celtics are coming for the No. 1 seed in the Eastern Conference. Winners of eight of their last 10, they're just 2.5 games behind the Detroit Pistons, who have lost their last four games.
The C’s have looked every bit of a true title threat, but with F Jayson Tatum back in the fold, that has gone to a whole new level. A 20-point win at home over the Dallas Mavericks in his first game back was nice, but somewhat expected. An 11-point win in Cleveland against the Cavaliers was much more impressive.
It’s taken this team no time to jell following Tatum’s return, and he has somehow looked like the Tatum he was before he tore his Achilles.
We could be watching a dynasty being born with the Spurs. This team is young but has followed the competitive mindset of its best player, C Victor Wembanyama, and is steamrolling the NBA, winning four straight games and 15 of its last 16.
San Antonio has the second-best record in the NBA and sits just three games back of the Oklahoma City Thunder for the No. 1 seed in the Western Conference.
“Yes” on both the Celtics and the Spurs to hoist this year’s Larry O’Brien Trophy is currently returning a 5.55x payout on PrizePicks Team Picks.
Celtics vs. Spurs Spread, Over/Under
The Spurs enter Tuesday’s game as 4.5-point home favorites, returning a 1.63x payout on PrizePicks Team Picks if they win outright.
The Celtics are road underdogs with a 2.12x payout if they win, via PrizePicks Team Picks, where you can earn money with your picks in 35 states.
- Spread: San Antonio Spurs -4.5 (2x payout)
- Over/Under: 222.5 (1.81x payout on over)
- Game Winner Payout: Celtics 2.12x | Spurs 1.63x
Team Picks payouts are live as of publishing and are subject to change.
Celtics vs. Spurs Injury Report
Let’s dive into the full Celtics vs. Spurs injury report for Tuesday, via NBA.com.
Boston Celtics Injury Report
- G Payton Pritchard (neck): Questionable
- SG Baylor Scheierman (thumb): Available
- C Nikola Vucevic (finger): OUT
San Antonio Spurs Injury Report
- SF Harrison Barnes (ankle): OUT
- C Mason Plumlee (conditioning): Questionable
- SG Lindy Waters III (illness): Questionable
Celtics vs. Spurs Prediction on Spread
Here are the key stats to know before locking in your Celtics vs. Spurs prediction on the spread for Tuesday, March 10, on PrizePicks.
- The Celtics are 22-11-0 (66.7%) against the spread (ATS) on the road, the best cover percentage in the NBA.
- For the season, the Celtics have the second-best net rating (+8.2), one point better than the Spurs (+7.2).
- Over their last 10 games, San Antonio has the best net rating in the NBA (+13.6), only 1.6 points better than the Celtics over that same span (+12).
- This is a great stylistic matchup for the Celtics because teams struggle most against the Spurs when they rely on paint scoring, which is wiped out by Wembanyama.
- Boston ranks 25th in percentage of points scored from 2-point range (47%). Head coach Joe Mazzulla and the C’s shoot the third-most 3-pointers in the NBA at 42.4 per game.
Celtics vs. Spurs Picks for PrizePicks Today: 3/10/26
Here are two of the top Celtics vs. Spurs to consider for Tuesday, March 10, on PrizePicks. Today’s NBA picks for PrizePicks are headlined by F Jaylen Brown and C Victor Wembanyama.
Celtics F Jaylen Brown vs. Spurs Projection: 37.5 Pts + Rebs + Asts
- Brown is averaging 41 points, rebounds, and assists (PRA) per game. On the road, that number increases to 43.5.
- JB is averaging a career-high 7.2 rebounds and 5.1 assists. In February, those numbers increased to 8.7 and 5.2, respectively. So far in March, those figures have increased even further to 8.8 and 7.5.
- Brown has gone over this projection in both games since Tatum has returned, posting 24-7-7 (41 PRA) and 23-9-8 (40 PRA).
- This is a notable tempo-up game for the Celtics, who rank last in the NBA in pace, facing the Spurs, who rank 12th.
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Spurs C Victor Wembanyama vs. Pistons Projection: 37.5 Pts + Rebs + Asts
- Wemby is averaging 37.9 PRA, but at home, that number rises to 39.9.
- This increase in production is because he averages 1.6 more rebounds, 0.3 more assists, and 2 more PPG in San Antonio.
- Wembanyama has gone over this projection in his last three games, all against great defensive teams in the Houston Rockets, Los Angeles Clippers, and Pistons.
- Boston allows opponents to shoot the sixth-most 3-point attempts per game (38.8). At home, Wemby tries 5.5 3-pointers per game at a career-high 36.2% clip.
Make Celtics vs. Spurs Picks on PrizePicks
We may be looking at a potential NBA Finals preview tonight in San Antonio, but Celtics vs. Spurs picks aren’t the only way hoops fans can get in on the daily NBA action.
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