Cavaliers vs. Raptors Prediction, Monday NBA Picks: Target Donovan Mitchell?

Cavaliers SG Donovan Mitchell reacts during an NBA game.
AP Photo/Sue Ogrocki

The NBA brings us a huge Eastern Conference matchup between the Cleveland Cavaliers (12-6) vs. Toronto Raptors (12-5) at 7 p.m. ET on Peacock tonight, Monday, November 24.

Below, we’ll break down our Cavaliers vs. Raptors prediction and player picks for Monday, including the top picks on PrizePicks' real-money NBA game for F-G Scottie Barnes and SG Donovan Mitchell.

These teams will face each other for the third and final time this season. The Raptors have already secured the season series by winning the two previous games in Cleveland and will aim to finish the series sweep in front of their home crowd. Both teams look like potential Eastern Conference juggernauts, with the Raptors holding the second seed and the Cavs right behind in third.

Let's get into our Cavaliers vs. Raptors prediction and player picks on PrizePicks tonight, including star Donovan Mitchell and Scottie Barnes going head-to-head.

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Cavaliers vs. Raptors Prediction, Preview for Monday, Nov. 24

Let’s break down Cleveland and Toronto as they head into this top-three Eastern Conference matchup on Monday, November 24 on Peacock tonight.

Cleveland Cavaliers Preview vs. Raptors

  • While they didn’t match their run of 15 consecutive wins to start the 2024-25 season, they still went an impressive 10-5 to begin this season.
  • At 12-6 overall, they currently hold the third seed in the Eastern Conference.
  • Cleveland’s success is due to being one of the league's most balanced teams. They enter this game as one of three teams in the top ten in both adjusted offensive and defensive ratings.
  • This success is despite the Cavs' lineup dealing with injuries throughout the season. PG Darius Garland returned on November 21st against the Pacers, but missed 13 games with a toe injury. Max Strus (foot) has yet to play this season, and Jarrett Allen (finger) has missed the last two games.
  • The Cavs have a laundry list of injuries vs. the Raptors tonight, including Darius Garland (injury management), Jarrett Allen (finger), De'Andre Hunter (rest), Sam Merrill (hand), and Craig Porter Jr. (hamstring) all listed as out.

Toronto Raptors Preview vs. Cavaliers

  • After missing the playoffs for the past three seasons, the Raptors are looking strong, currently holding the second seed in the Eastern Conference.
  • Toronto is an NBA Cup contender, becoming the first team to advance to the knockout round with its win over the Wizards on Friday.
  • This team is making its mark early in the season, as they just set a franchise record for five straight games of shooting at least 50% from the floor.
  • The Raptors are coming into this game with an eight-game winning streak, which ties for their best mark since January and February 2022.
  • The Raptors will be without RJ Barrett (knee) tonight, as he's been ruled out.

Cavaliers vs. Raptors Picks for PrizePicks – Monday, 11/24/25

Below are three top Cavaliers vs. Raptors picks for PrizePicks NBA onMonday. Use PrizePicks real-money NBA game and win real money if your NBA pick is correct.

Raptors F-G Scottie Barnes Projection: 28.5 Pts+Reb

  • In Barnes’ lone game against the Cavaliers this season, he led the team with 28 points and 10 rebounds.
  • Barnes has had success against Cavaliers F Evan Mobley in the past. He’s averaging 17.0 points and 7.9 rebounds in 15 career head-to-head matchups.
  • Barnes' usages jumps from 27% with Barrett on the floor to 29.8% without him. Barrett is out tonight vs. the Cavs.
  • The Cavs are allowing the most points (27.9) and rebounds (12.8) to power forwards this season.
  • Cleveland ranks 16th in allowing 11.6 offensive rebounds per game.
  • Barnes grabs the rebound on 16.2% of his own misses, which is in the 100th percentile.
  • The Cavs are allowing 32.8% of opponents' field goal attempts from within five feet.
  • Barnes is taking 5.6 shots per game from within five feet, which is in the 90th percentile.
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Raptors PG Immanuel Quickley Projection: 6 Assists

  • The Cavaliers are 18th in assists allowed per game at 27.0.
  • Immanuel Quickley is 17th in the league with a 29.1 assist ratio.
  • His assist ratio jumps to 39.9% with Barrett off the court, per Add More Funds.
  • Quickley has 6 assists in both matchups this year against the Cavs.
  • The guard out of Kentucky has 7+ assists in five of seven home games this season.
  • Cleveland is allowing 8.6 assists per game on the road to point guards, which is the fourth-most. 
  • 66.2% of the field goals allowed by the Cavaliers were assisted, ranking 26th.

Cavaliers SG Donovan Mitchell Projection: 28.5 Points

  • Mitchell is fifth in the league in scoring per game, averaging 30.8 points per game.
  • The Cavs guard has more than 28 points in five of his last six games.
  • Mitchell has played one game against the Raptors this season. He led that game with 31 points. 
  • Mitchell should have the ball in his hands plenty tonight due to all of the injuries; Mitchell has a 31.4% usage rate overall since last year; that jumps to 31.6% without Allen.
  • Mitchell scored 31 points vs. the Raptors last week in his lone game against them this season.
  • The former Jazz guard is heavily involved in the Cavs' offense, ranking seventh in usage percentage (30.9%) this year.

Make Monday NBA Picks on PrizePicks

On Monday, the NBA offers a 10-game slate featuring some excellent matchups. One of the top matchups features Mitchell and the Cavs going up to Toronto to avoid losing all three games to Barnes and the Raptors.

In an Eastern Conference matchup, there are plenty of options to make your NBA picks on PrizePicks. Just predict More or Less on NBA player projections and win money if you're right.

Check out the Playbook for more PrizePicks NBA picks and analysis all the way through the season.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

about the author

John is a graduate from Quinnipiac University with a Master’s Degree in Sports Journalism. With almost 15 years working in radio, TV and blogs, it includes stops at ESPN, NBC Sports, and Audacy. Along with being an avid sports fan, he is into fitness and cooking.

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