The Buffalo Bills and Chicago Bears will showdown showdown in NFL Preseason Week 2 in Chicago, with kickoff set for 8 p.m. ET on Sunday, Aug. 17, televised nationally on FOX.
Below, we'll get into the top Bills vs. Bears predictions and NFL picks for tonight's preseason game, including four player picks for PrizePicks tonight.
After losing to the Giants, Buffalo goes on the road for the first time in the preseason. They’ll have to do so against a Bears team that will p[lay their first-team, including QB Caleb Williams — who has not had a strong training camp.
Meanwhile, we're unlikely to see the Bills play their starters tonight, including QB Josh Allen.
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Bills vs. Bears Predictions, NFL Picks on Sunday
Here are four of the top Bills vs. Bears predictions and NFL DFS picks on PrizePicks. Use this NFL preseason DFS analysis to help you build a Lineup on PrizePicks for Sunday, Aug. 17. Click each pick to read more.
- Bears QB Caleb Williams — 54.5 Passing Yards
- Bills QB Mitchell Trubisky — 87.5 Passing Yards
- Bills RB Frank Gore — 28.5 Rushing Yards
- Bears RB Kyle Monangai — 23.5 Rushing Yards
Bears QB Caleb Williams — 54.5 Passing Yards
- The 23-year-old second-year QB will see his first taste of 2025 preseason action after the other three quarterbacks suited up last week.
- It's Williams first live game action under new HC Ben Johnson, though it's unknown exactly how much he will play tonight.
- Buffalo allowed 317 total passing yards against four Giants quarterbacks in preseason Week 1.
- Williams last threw for 148 yards and 1 TD on January 5 vs. the Packers.
- This will be Williams’ first time squaring off against the Buffalo Bills.
Bills QB Mitchell Trubisky — 87.5 Rushing Yards
- Mich Trubisky’s 13 pass attempts in the Bills preseason opener were tied for the most on the team — it should remain similar with Allen not likely to play.
- The former Bears QB threw 138 yards with a touchdown past last week.
- At 30-years-old, Trubisky returns to the Bills this season after he played in Buffalo in 2021 as a reserve.
- Trubisky will square off with the team that drafted him No. 2 overall in 2017 for the first time. He left the team in 2020.
Bills RB Frank Gore Jr. — 30.5 Rushing Yards
- Gore had 33% of the team’s rushing attempts in Week 1 of the preseason.
- An 11-yard run helped his five attempts reach 21 total yards.
- The 23-year-old recorded 212 yards in last year’s preseason.
- Chicago allowed 101 rushing yards against Miami last week.
Bears RB Kyle Monangai — 24.5 Rushing Yards
- Seventh-round rookie Kyle Monangai led the Bears with his 30 rushing yards last week.
- It took the 23-year-old only 6 carries to reach that number, averaging 5 yards per carry.
- The four-year Rutgers RB had the longest carry (13 yards) of the day for Chicago.
- Buffalo held the Giants to just 3.2 yards per carry.
Make NFL Picks on PrizePicks
Sunday's two NFL preseason games are highlighted by the Bears hosting the Bills at 8 p.m. ET on FOX tonight. With two NFL games on tap, now is time to build your NFL Lineup on PrizePicks.
Just pick More or Less at least two NFL player stat projections to build your Lineup on PrizePicks, including the Bears starters as they will start their first unit tonightl. Use the players above to build your Lineups around, or use a 6-Pick Lineup to reach up to 2000x payouts.
Check out the Playbook for more NFL DFS picks and analysis all the way through the season.
