The AFC wild card race heats up when the Cincinnati Bengals (4-8) face off against the Buffalo Bills (8-4) on Sunday. This Week 14 matchup kicks off at Highmark Stadium in Orchard Park, NY, at 1:00 p.m. ET on FOX.
After a dominant 32-14 Thanksgiving win over Baltimore, Cincinnati travels to Buffalo with its season on the line. Bengals QB Joe Burrow’s return has reignited the Bengals’ offense, but a depleted defense faces a tall task against Bills QB Josh Allen and one of the AFC’s most potent offenses.
Below, we’ll take a look at a Bengals vs. Bills prediction and picks for NFL Week 14 on PrizePicks.
Bengals vs. Bills Prediction, Preview for NFL Week 14
Here’s how the Cincinnati Bengals and Buffalo Bills stack up heading into this Week 14 matchup.
Cincinnati Bengals Preview vs. Bills
- The Bengals head to Buffalo on a mission after throttling Baltimore on Thanksgiving, but face a steep hill to climb with a bad defense.
- Cincy is facing elimination, with playoff chances dropping to 1% if they lose Sunday, making this a do-or-die matchup.
- Star DE Trey Hendrickson has been ruled out with a hip/pelvis injury, further crippling Cincinnati's already struggling defense.
- Burrow and the offense have regained rhythm, but they may be tested against Buffalo in brutally cold weather at Highmark Stadium.
Buffalo Bills Preview vs. Bengals
- The Bills boast the league's premier passing defense, allowing just 163.2 YPG, and held the Steelers to 108 yards through the air in Week 13.
- Allen has totaled 30 TDs (19 passing, 11 rushing) through 12 games, showcasing the ability needed to exploit Cincinnati's league-worst defense.
- Bills RB James Cook is second in the NFL in rushing yards with 1,228, just 54 yards behind the leader, Jonathan Taylor. The team's ground game has accumulated 155.7 YPG and 21 TDs, ranking near the top in the NFL.
- Buffalo will be without DE Joey Bosa and LB Terrel Bernard against a Bengals offense now at full strength.
Bengals vs. Bills Spread, Total for NFL Week 14
The Bengals enter this matchup as 6.5-point road underdogs, returning a 3.12x payout on PrizePicks Team Picks if they win outright.
The Bills are home favorites with a 1.33x payout if they win, via PrizePicks Team Picks.
- Spread: Buffalo Bills -6.5
- Total: 53.5
- Game Winner Payout: Bengals 3.12x | Bills 1.33x
Payouts as of Saturday, 10:30 a.m. ET and are subject to change.
Bengals vs. Bills Picks for PrizePicks, NFL Week 14
Here are the top Bengals vs. Bills Week 14 picks on PrizePicks’ real-money NFL game, including QBs Joe Burrow and Josh Allen.
Bengals QB Joe Burrow vs. Bills Projection: 252.5 Pass Yards
- In his Week 13 return from a nine-game absence, Burrow immediately threw a massive 46 passes for 261 yards, which tied for his season-high in attempts.
- The Bengals' defense ranks dead last in passing yards allowed (256.8 YPG). With that in mind, Burrow might need to handle the load on offense to go toe-to-toe with Allen and the high-powered Bills offense.
- The Bengals’ offensive line has seen improvements in recent weeks, allowing just one sack against Baltimore while giving Burrow 2.44 seconds to throw. This could bode well for the star QB, as Buffalo’s pass rush is significantly compromised after Bosa suffered his injury.
- With Higgins back in action after suffering a concussion in Week 12, Burrow has a full cast of playmakers to combat a stingy pass defense.
Bills QB Josh Allen vs. Bengals Projection: 234.5 Pass Yards
- Allen is averaging 236 passing YPG (2,832 total) with 8.1 yards per attempt. He has exceeded 250 passing yards in four of his last five starts, averaging nearly 280 YPG in that span.
- Cincinnati’s defensive front ranks 30th in pass-rush win rate (29%) and records just 1.5 sacks per game. Without Hendrickson, Allen could have all the time in the world to dissect the secondary.
- With a projected game total of 53.5 and the Bengals’ offense averaging 26.7 PPG with Burrow, there is a potential shootout on our hands between two of the league’s premier offenses.
Bills RB James Cook vs. Bengals Projection: 99.5 Rush Yards
- RB James Cook is averaging 19.3 carries per game, ranking second in the NFL with 231 attempts while posting 1,228 rushing yards.
- The Bills are 6-1 when he receives 20+ carries, including a career-high 32 totes in Week 13’s win over Pittsburgh.
- Buffalo’s RB has recorded seven 100-yard rushing games this year (tied for most in Bills history through 12 games).
- Bengals rank 31st in rush defense at 153.3 YPG allowed, with five RBs eclipsing 100 yards against them.
- Should the Bills control clock against a Bengals defense allowing 32.7 PPG and 6.3 yards per play, Cook could earn heavy involvement to stretch the game.
Make Bengals vs. Bills NFL Week 14 Picks on PrizePicks
The Bengals vs. Bills Week 14 matchup presents plenty of opportunities to put your NFL minds to the test.
Burrow aims to keep the offense flowing against a tough Bills pass defense. Meanwhile, Allen and Cook will aim to take it to the vulnerable Bengals defense as they push toward the playoffs.
With PrizePicks, you can make Bengals vs. Bills predictions and win real money on your picks. Just pick players, predict More or Less on their projected stats, and cash out if you're right.
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