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Arsenal vs. Newcastle Prediction, Picks, XIs for EPL – Saturday, April 25

Arsenal F Viktor Gyokeres warms up for the Champions League quarterfinals.
AP Photo/Armando Franca

Arsenal vs. Newcastle is set to kick off at 12:30 p.m. ET on Saturday, April 25, with Arsenal entering as 1.36x favorites, via PrizePicks. 

Arsenal looks to regain its spot at the top of the table after Man City overtook it on goal difference during the midweek. The Gunners have gone over a month without a win in the Premier League.

Newcastle’s mediocre season has it likely to remain in the bottom half of the table, barring any unexpected results. Eddie Howe’s squad enters Saturday’s contest as large road underdogs, with several key players slated to miss the match with injuries. 

Below, we'll break down our Arsenal vs. Newcastle prediction and picks for Saturday's EPL match, including the spread, total goals, and key player picks for PrizePicks.

Make your Arsenal vs. Newcastle prediction on PrizePicks now for Saturday's EPL match.

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Arsenal vs. Newcastle Prediction, Picks for Premier League – Saturday, April 25

It seems like just the other day Arsenal was nine points ahead of everyone atop the EPL table. Now, after over 200 days of owning that top spot, Arsenal heads into Saturday afternoon’s match as the second-placed team.

Mikel Arteta’s squad will be eager to avoid finishing as runners-up for the fourth consecutive season. The Gunners should have some much-needed reinforcements returning in this match, headlined by club vice-captain Bukayo Saka. Saka was out of commission for just under a month due to an Achilles issue.

Arsenal’s attack has struggled in his absence, with the club scoring just 4 goals in its last five games across all competitions. Luckily for the Gunners, Newcastle has struggled defensively as of late and will be missing key players in the back line in this one. Veteran defender Fabian Schar and Valentino Livramento are both set to miss this match with lower-body injuries.

Neither club enters this match in particularly good form, with Newcastle losing four straight matches — three of them coming in the EPL. Howe’s team has conceded 6 goals in that three-game span. We already touched on Arsenal’s recent woes; however, Saturday afternoon’s matchup could be a chance to right the ship at home against a struggling opponent.

Arsenal miraculously defeated Newcastle the first time these teams met, all the way back in matchweek 6. The Gunners were down 1-0 as late as the 83rd minute. Thanks to the heroics of Mikel Merino and Gabriel, Arsenal went on to secure three points on the road back in late September. 

Arteta will hope to replicate the fluidity the attack had at that point in the season. Arsenal had 20 shots, 7 on target, in that match, compared to its most recent defeat, when it finished with 9 shots and just 3 on target. The Gunners will bank on the return of Saka, alongside many quality players in the squad, to leapfrog them forward and past Man City for good.

Will Arsenal win and take first place in the Premier League? Make your prediction on PrizePicks Team Picks and earn money if you're right.


Arsenal vs. Newcastle Spread, Total Goals, Payouts – 4/25/26

Arsenal enters Saturday’s game as home favorites against Newcastle, returning a 1.38x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for the Arsenal vs. Newcastle game on PrizePicks.

  • Winner Payout: Arsenal – 1.36x | Tie – 4.34x | Newcastle – 5.88x
  • Spread: Arsenal -1.5 (2.12x Payout)
  • Total Goals: 2.5 (Over – 1.66x)
  • Both Teams to Score: Yes 1.81x | No 1.88x

Play the Arsenal vs. Newcastle match winner or total goals on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.


Arsenal vs. Newcastle Prediction on Total Goals for Premier League – 4/25/26

Here are the key game stats and trends behind our Arsenal vs. Newcastle prediction on total goals for Saturday, April 25. Check out more of our soccer picks and predictions on PrizePicks.

  • Arsenal matches have gone over 2.5 total goals in back-to-back EPL contests for the first time since February.
  • Newcastle has surpassed this threshold far more often, with over 2.5 total goals in 9 of its last 10 matches in the EPL.
  • Arsenal are averaging just under 2 goals per game in the Prem this season. However, the last time they scored at least 2 goals was March 14. 
  • Newcastle’s goals scored and conceded are both around 1.5 per game this season. 
  • Arsenal has dominated at the Emirates Stadium in the EPL with a 36 to 11 goal differential over 16 games this season. The Gunners' goals per home game are about +0.3 goals higher than a combination of home and away games. 

Arsenal vs. Newcastle Projected Lineups for Saturday, April 25

Take a look at the Arsenal vs. Newcastle projected lineups for today's EPL match. Lineups are not official and should be confirmed before the match starts.

Arsenal Lineup vs. Newcastle: Projected 4-3-3

Goalkeeper: David Raya

Defense: Ben White, William Saliba, Gabriel, Piero Hincapie

Midfield: Martin Odegaard, Martin Zubimendi, Declan Rice

Forwards: Bukayo Saka, Viktor Gyokeres, Eberechi Eze

Newcastle Lineup vs. Arsenal: Projected 4-3-3

Goalkeeper: Aaron Ramsdale

Defense: Lewis Hall, Sven Botman, Malick Thiaw, Kieran Trippier

Midfield: Bruno Guimaraes, Sandro Tonali, Lewis Miley

Forwards: Harvey Barnes, William Osula, Joe Murphy


Arsenal vs. Newcastle Player Picks, Stats for PrizePicks – 4/25/26

Here are the top Arsenal vs. Newcastle picks to target on PrizePicks for Saturday, April 25. Today’s EPL picks for PrizePicks include Viktor Gyokeres and Aaron Ramsdale.

Arsenal F Viktor Gyokeres vs. Newcastle

Viktor Gyokeres Projections via PrizePicks: 0.5 Goal (Demon), 0.5 Shots on Target (Goblin), 1.5 Shots (Goblin) 

  • Viktor Gyokeres is Arsenal’s top goal scorer (12) in the Premier League this season.
  • The Swedish striker has scored 2 of his 12 goals in his last five games.
  • Gyokeres averages just 0.6 shots on target per game. However, Newcastle has allowed 4 shots on target vs. strikers over its last three matches (1.3 shots on target per game).
  • The 27-year-old attacker averages 1.5 shots per game. Over his last five starts in the Prem, Gyokeres averaged slightly more at 1.8 shots per match.

Add Viktor Gyokeres to your PrizePicks Lineup now


Newcastle GK Aaron Ramsdale vs. Arsenal

Aaron Ramsdale Projections via PrizePicks: 3.5 Goalie Saves, 36.5 Passes Attempted

  • Aaron Ramsdale has just one clean sheet in his 11 EPL starts. The former Arsenal keeper is conceding 1.4 goals per game heading into this matchup. 
  • Over his last five EPL matches, Ramsdale posted more than 3.5 saves just twice.
  • The English keeper’s 60% save rate would rank last in the league if he had enough games played to count the stat.
  • Ramsdale is averaging just under 36.5 (36.36) passes attempted per game. Goalkeepers are averaging just 29.2 passes against Arsenal over the last five games.

Add Aaron Ramsdale to your PrizePicks Lineup now

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Make Your Arsenal vs. Newcastle EPL Picks on PrizePicks

Arsenal will look to reclaim first place in the EPL table when they host Newcastle on Saturday afternoon. Newcastle searches for some revenge following the last meeting in September.

Don’t wait — you can make your Arsenal vs. Newcastle picks now on PrizePicks and PrizePicks Team Picks to earn real money. 

Just pick players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states

Stick around with the Playbook for continued soccer and EPL predictions, picks, and analysis.

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Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Anthony is a journalist based in South Florida who specializes in sports content. He has covered the NFL, NBA, UFL, March Madness, the World Cup, the English Premier League, and the Champions League.

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