Arsenal vs. Chelsea Prediction, Picks, XIs for EPL – Sunday, September 6

Sunday’s Premier League match between Arsenal and Chelsea is set to kick off at 11:30 a.m. ET. Arsenal enters the match as slight favorites on their home pitch, returning a 1.66x payout on PrizePicks.

The champions of England have jumped out to a perfect start, grabbing all 6 points from their first two games this season. Arsenal are one of two teams yet to concede a goal and now take on their biggest rivals in a London derby on Sunday morning.

Chelsea have had the picture-perfect start to life under new manager Xabi Alonso, winning their first two contests and scoring 7 goals in the process. They'll now look to dethrone the reigning champions and defeat Arsenal for the first time since 2021.

Below, we'll break down our Arsenal vs. Chelsea prediction and picks for Sunday's Premier League match, including winner payouts, total goals, and top EPL picks for PrizePicks today.

Make your Arsenal vs. Chelsea picks on PrizePicks for Sunday’s match now.

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Arsenal vs. Chelsea Prediction, Picks for EPL – Sunday, September 6

How to watch Arsenal vs. Chelsea: USA (English) / Telemundo(Spanish)

Kickoff Time: 11:30 a.m. ET

Venue: Emirates Stadium, London, England

One of the Premier League's biggest rivalries is set for Sunday morning, with both sides arriving unbeaten after two games. Chelsea's new-look front three has hit the ground running, with LW Morgan Rogers, ST João Pedro, and RW Cole Palmer combining for 9 goal contributions across just two Premier League appearances.

Now, they face arguably the best defensive unit in club football over the past few seasons.

Arsenal are yet to concede a goal despite the absence of two key defenders. CB William Saliba and RB Jurrien Timber continue to miss time, yet the Gunners have not been troubled defensively.

GK David Raya has been called upon to make just one save across the opening two games, with opponents generating a combined 0.53 xG against Arsenal's backline. Saliba's primary replacement, CB Cristhian Mosquera, is expected to miss Sunday's game, leaving summer signing CB Ezri Konsa as the most likely starter in Mikel Arteta's back four.

Arsenal may dominate possession in this one, particularly based on what we've seen from Alonso's Chelsea in the opening weeks. The Blues had the ball just 26% of the time in their most recent win and have been content to invite pressure and attack on the counter.

With Arsenal exceeding 60% possession in both of their matches, it could be another lopsided battle for the ball on Sunday.

Ultimately, Arsenal will need to remain defensively disciplined against Chelsea's counter-attacking threat while creating enough of their own chances against a Blues backline that has looked vulnerable in the early stages of the season.

Arsenal vs. Chelsea Spread, Total Goals, Payouts – Sunday, September 6

Arsenal enters Sunday’s game as home favorites against Chelsea, returning a 1.66x payout if they win outright, via PrizePicks Team Picks.

Meanwhile, Chelsea will look to pull off a massive upset as underdogs on the road (4.16x payout). PrizePicks has a 3.7x payout on a draw between the two sides.

Here are the full payouts for the Arsenal vs. Chelsea game on PrizePicks.

‍Play the Arsenal vs. Chelsea spread or total goals on PrizePicks Team Picks.

Team Picks data is live at the time of writing and is subject to change.

Arsenal vs. Chelsea Prediction on Total Goals – 9/6/26

Here are the key game stats and trends behind our Arsenal vs. Chelsea prediction on total goals for the Premier League match on Sunday, September 6.

Check out more of our EPL picks and predictions on PrizePicks.

• Chelsea matches are averaging 6 total goals through the first two Premier League fixtures under Alonso, with the Blues scoring a league-high 7 goals in that span.
• After scoring 3 goals in their opener, Arsenal managed just 1 in their most recent match against Aston Villa, registering only 2 shots on target in that game.
• Only one of the last four Premier League meetings between these sides has produced more than 2.5 total goals.
• Chelsea have created the second-most big chances in the Premier League this season with 10. Arsenal rank toward the bottom of the league with just 3 big chances created through two matches.
• Arsenal have allowed just 1 shot on target across their first two games combined. Aston Villa failed to register a single shot on target and generated just 0.33 xG against Arsenal's defense.

Predict Arsenal vs. Chelsea total goals on PrizePicks.

Arsenal vs. Chelsea Projected Lineups for Premier League – Sunday, September 6

Take a look at the Arsenal vs. Chelsea projected lineups for today's EPL match. Lineups are not official and should be confirmed before match start.

Arsenal Lineup vs. Chelsea: Projected 4-2-3-1

• Goalkeeper: David Raya
• Defense: Ben White, Ezri Konsa, Gabriel Magalães, Riccardo Calafiori
• Midfield: Myles Lewis-Skelly, Declan Rice, Martin Ødegaard
• Forwards: Bukayo Saka, Kai Havertz, Christos Tzolis

Chelsea Lineup vs. Arsenal: Projected 3-4-2-1

• Goalkeeper: Emi Martínez
• Defense: Wesley Fofana, Maxence Lacroix, Levi Colwill
• Midfield: Jorrel Hato, Roméo Lavia, Malo Gusto, Pedro Neto
• Forwards: Morgan Rogers, João Pedro, Cole Palmer

Arsenal vs. Chelsea Picks, Player Stats for PrizePicks: 9/6/26

Here are Arsenal vs. Chelsea picks to target for the Premier League on Sunday, September 6. Today’s EPL picks include Kai Havertz and Cole Palmer.

Arsenal ST Kai Havertz vs. Chelsea: 2.5 Shots

• Arteta has deployed the versatile Havertz primarily as a striker to open the season. The German international has scored 2 goals across all competitions.
• The former Chelsea man has a strong record against his old club, scoring 3 goals in six appearances against the Blues since joining Arsenal in 2023 — all while averaging just 1.0 shots per game in those matches.
• Chelsea have conceded 29 total shots across their first two Premier League games, with opposing strikers averaging 2.0 SPG in those fixtures. 

Add Kai Havertz to your PrizePicks EPL lineup now!

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Chelsea RW Cole Palmer vs. Arsenal: 1.5 Shots Assisted

• After an injury-hit 2025-26 Premier League campaign, Palmer has come out firing, averaging 3.33 key passes per game across all competitions.
• The Englishman played just 116 minutes against Arsenal last season, missing two of their four meetings. He managed 1 key pass across his two showings.
• Chelsea are averaging just over 20 shots per game as a team across all competitions, with Palmer accounting for 5.7 of those — leaving plenty of opportunities for his teammates.

 Add Cole Palmer to your PrizePicks EPL lineup now!

Make Arsenal vs. Chelsea Picks on PrizePicks

Arsenal will look to continue their title defense when they host Chelsea on Sunday. Chelsea, meanwhile, hopes to prove they’re genuine contenders by upsetting their London rivals to start the season with three straight wins.

Don’t wait until kickoff — you can make your Arsenal vs. Chelsea picks for Sunday’s EPL match now on PrizePicks to earn real money. 

Just pick your Premier League players, predict More or Less on their stats, and cash in if you’re right. With Team Picks, you can make predictions on the match winner, total goals, and both teams to score — now available in 36 states.

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