The Arizona Wildcats (28-2) own the top seed heading into next week’s Big 12 tournament in Kansas City. The Wildcats picked up a pair of crucial home victories over Kansas (84-61) and Iowa State (73-57) in the last week to wrap up the conference title.
The Colorado Buffaloes (17-13), meanwhile, overcame a slow start in league play to win three of their past four games.
Let’s look at an Arizona vs. Colorado prediction for Saturday’s battle at CU Events Center in Boulder, tipping off at 11:00 p.m. ET on ESPN2. Make your CBB picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!
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Arizona vs. Colorado Prediction, Spread, Over/Under
The Wildcats have defeated the Buffaloes in five straight meetings, dating back to their days in the Pac-12.
Arizona captured the first matchup as Big 12 rivals last February in Tucson, 78-63, as 14.5-point favorites.
Colorado’s last victory over Arizona came in Boulder as 9.5-point underdogs, 79-63, in 2022.
Arizona vs. Colorado Spread, Over/Under
The Wildcats enter this matchup as 14.5-point road favorites, returning a 1.06x payout on PrizePicks Team Picks if they win outright.
The Buffaloes are home underdogs with a 7.14x payout if they win, where you can earn money with your picks in 34 states.
- Spread: Arizona Wildcats -14.5
- Over/Under: 155.5
- Game Winner Payout: Arizona 1.06x | Colorado 7.14x
Team Picks data is live as of writing and is subject to change.
Arizona vs. Colorado Prediction on Spread
Here are some key stats to know before locking in your Arizona vs. Colorado prediction on the spread for Saturday, March 7 on PrizePicks.
- The Wildcats have failed to cover in their last three opportunities as a road favorite. In three of its last five away contests, Arizona allowed 80+ points.
- Colorado overcame a six-game slide to close January to win five of its nine contests. The Buffaloes are 5-2 against the spread since February 7.
- CU seeks its fifth consecutive home victory, with the best win yet coming as short dogs against TCU, 87-61, on February 1.
- Colorado hasn't lost a home game by more than 10 points this season. The Buffs previously logged a 2-point defeat to Texas Tech and a 6-point setback to Kansas.
- The Wildcats limited Kansas to 39.2% shooting on effective field goal percentage, then held Iowa State to 34.6%.
- Arizona has not given up less than a 40% eFG% in three straight games all season.
- Colorado ranks 341st in the country in defensive 3-point percentage (37%), however, the Buffs have held opponents to 25% from deep in their last four home games.
Arizona vs. Colorado Picks for PrizePicks Today: 3/7/26
Here are three top Arizona vs. Colorado picks to target on Saturday, March 7. Key PrizePicks player projections are headlined by three players: Colorado G Isaiah Johnson, Arizona G Brayden Burries, and Wildcats G Jaden Bradley.
Colorado G Isaiah Johnson vs. Arizona Projection: 16.5 Points
- The star freshman leads the Buffs in scoring at 16.6 points per game (PPG).
- In each of the last three games, Johnson topped the 18-point mark. He posted 22 points in Tuesday’s victory at Utah.
- Johnson topped this projection in his last home outing, checking in with an 18-point effort against Kansas State.
- Johnson compiled at least 18 points in five of six conference games against ranked opponents.
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Arizona G Brayden Burries vs. Colorado Projection: 17.5 Points
- Another freshman standout leads his team in scoring, putting up 15.5 PPG.
- Following consecutive 20+ point efforts against Baylor and Kansas, Burries was held to 11 points in Monday’s rout of Iowa State.
- In four of the last six road games, Burries has scored at least 18 points. Three times in this stretch, he's compiled more than 24 points.
- Burries has knocked down 12 of 26 attempts (46.1%) from 3-point range in his past seven games away from Tucson.
Arizona G Jaden Bradley vs. Colorado Projection: 21 Pts + Rebs
- The senior is averaging a career-high 13.9 PPG, a slight jump from 12.1 PPG last season.
- In last season’s victory over Colorado, Bradley was held to 7 points and 2 rebounds.
- Since scoring 26 points against BYU on January 26, Bradley's finished below this projection in eight of nine games.
- In the last nine contests, Bradley has failed to knock down a 3-pointer eight times.
Make #2 Arizona vs. Colorado Picks on PrizePicks
The Wildcats are guaranteed the top seed in the Big 12 tournament and track to be a #1 seed in the NCAA Tournament. Will they continue to roll, or get tripped up at Colorado in the regular-season finale?
You can make your Arizona vs. Colorado picks on PrizePicks and PrizePicks Team Picks to earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states.
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