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76ers vs. Timberwolves Prediction, Spread, Picks: Anthony Edwards, More

Minnesota Timberwolves SG Anthony Edwards dunks over the Golden State Warriors during a game.
AP Photo/Godofredo A. Vásquez

Stars galore take the court on Sunday, with the NBA carrying 11 matchups for fans to choose from. A nighttime bout between the Philadelphia 76ers and Minnesota Timberwolves (7:00 p.m. ET) sees two conferences collide.

With both teams occupying the No. 6 seeds in their respective playoff races, there’s plenty to play for to cap off the weekend of hoops action. 

Below, we’ll break down our 76ers vs. Timberwolves prediction and picks for Sunday night’s game. Make your picks on PrizePicks and PrizePicks Team Picks and earn real money if you’re right, including on game winners, spreads, and totals!

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76ers vs. Timberwolves Prediction, Spread, Over/Under

Following an ugly 24-58 effort last season, the 76ers and head coach Nick Nurse have bounced back this year. Their 30-26 record has them teetering on play-in territory, but all it takes is one hot stretch to push for the Toronto Raptors' spot in the fifth seed.

Minnesota, meanwhile, has been to the Western Conference Finals in back-to-back years. After winning 49 games a season ago, they’re pacing to surpass the 50-victory mark now. Since a slow 10-8 start to the year, Chris Finch’s crew has gone 25-14. 

Sunday marks the 69th all-time meeting between these franchises in the regular season. With the series all knotted up at 34 apiece, something’s got to give in this clash. 

76ers vs. Timberwolves Spread, Over/Under

The 76ers enter Sunday’s game as 9.5-point road underdogs, returning a 3.44x payout on PrizePicks Team Picks if they win outright.

The Timberwolves are home favorites with a 1.26x payout if they win, via PrizePicks Team Picks.

  • Spread: Minnesota Timberwolves -9.5
  • Over/Under: 239.5
  • Game Winner Payout: 76ers 3.44x | Timberwolves 1.26x

Team Picks data is live at the time of writing and is subject to change.


76ers vs. Timberwolves Injury Report

Let’s dive into the full 76ers vs. Timberwolves injury report for Sunday, via NBA.com.

Philadelphia 76ers Injury Report

  • N/A — not yet submitted

It's worth noting that superstar C Joel Embiid (knee/shin) missed Saturday's game against the New Orleans Pelicans. He hasn't played since Feb 7 against the Phoenix Suns and was initially viewed as a game-time decision for Sunday.

Minnesota Timberwolves Injury Report

  • C Rudy Gobert (league suspension): OUT
  • PF Naz Reid (shoulder): Questionable

76ers vs. Timberwolves Prediction on Spread

Here are some stats to know to help you make your 76ers vs. Timberwolves prediction on Sunday, February 22.

  • Neither of these teams fares particularly well in non-conference outings. Philadelphia is 8-10 against the spread in such scenarios, with Minnesota being an even 10-10 ATS.
  • The 76ers may score the 14th-most points on a nightly basis (115.9), but they sit 26th in effective field goal percentage (52.8). 
  • Defensively, Nurse’s crew allows the fourth-most fastbreak PPG (16.9) and the third-most assists per made shot (0.658). 
  • Only three teams put the ball in the net more than the Timberwolves, who score 119.7 PPG and also sit fourth in eFG% (56.3). 
  • On the other end of the court, Minnesota cedes the eighth-fewest points per shot (1.134).

76ers vs. Timberwolves Picks for PrizePicks Today: 2/22/26

Here are three top 76ers vs. Timberwolves picks to target for Sunday, February 22 on PrizePicks. Player stat projections via PrizePicks are headlined by PG Tyrese Maxey, PF Julius Randle, and SG Anthony Edwards.

76ers PG Tyrese Maxey vs. Timberwolves Projection: 38.5 Pts + Rebs + Asts

  • Leading the league in minutes per game at 38.6, Maxey is having a career year with 21.5 shot attempts each night.
  • The sixth-year PG produces 39.7 points, rebounds, and assists per night on 59.5% true shooting.
  • Maxey’s 11.1% defensive rebounding rate marks a new career-high figure.
  • According to NBARAPM, Maxey spends 37% of his time on the ball and nets 20.2 assist points per 100 possessions. 

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Timberwolves PF Julius Randle vs. 76ers Projection: 29.5 Pts + Rebs

  • Randle brings home 29.1 points and rebounds each night. In his last eight contests dating back to January 31, that number is 29.4. 
  • The 12th-year big man’s 59.5 TS% is his best since 2018-19 as a member of the New Orleans Pelicans. 
  • Aside from his debut campaign when he played in just one game, Randle owns a double-digit rebounding percentage in every season. 
  • Per FantasyPros, the 76ers allow the second-most rebounds per game to the PF position at 11.01.

Timberwolves SG Anthony Edwards vs. 76ers Projection: 29.5 Points

  • Forty-seven games into the season, Edwards pours in exactly 29.5 points each night.
  • Edwards’ 31.6 shot attempts per 100 possessions puts him in the 100th percentile, via databallr
  • Ant Man’s career-high 62.0 TS% is fueled by new personal bests from every single scoring range: 0-3 feet (75.1%), 3-10 feet (45.6%), 10-16 feet (51.1%), 16 feet to the 3-point line (41.7%), and on treys (40.1%). 
  • Only three teams — the Pelicans, Washington Wizards, and Utah Jazz — surrender more PPG than the 76ers (23.18) to the SG spot.

Make 76ers vs. Timberwolves Picks on PrizePicks

76ers vs. Timberwolves picks aren’t the only avenue hoops fans have to getting in on the daily NBA action.

You can make your picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 34 states. 

Stick around with the Playbook for continued NBA predictions, picks, and news.

Get in the game! Sign up for PrizePicks and cash in on your sports predictions. Play $5 and get $50 instantly in Lineups with promo code PLAYBOOK.

Team Picks and Culture Picks are event contracts offered by Performance Predictions II, LLC d/b/a PrizePicks Predict, a CFTC-registered FCM and NFA Member. All event contract customers must be U.S. residents and 18+. Some event contracts may not be available in every state. Event contract trading carries significant risk and is not appropriate for everyone. No guarantee against loss is offered. Past results are not necessarily indicative of future results. Void where prohibited by law. Restrictions apply. For full terms of service see prizepicks.com/predict-regulatory. Team and Culture Pick Early Payouts subject to market liquidity. The content provided is for informational and educational purposes only and does not constitute investment advice, or a recommendation to trade any commodity interest.

about the author

Jordan Foote is a seasoned sports writer with years of experience covering the NFL, NBA and MLB for multiple outlets. He is a Baker University alumnus, earning his degree in Mass Media with an emphasis in sports journalism. Foote was born and raised in Kansas City, where he still resides to this day.

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