Las Vegas plays host to the 49ers vs. Raiders preseason game on Saturday at 4 p.m. ET. The matchup is headlined by the 2025 No. 6 overall pick, Raiders RB Ashton Jeanty, who is a top NFL preseason DFS pick today on PrizePicks.
Jeanty struggled in the team’s preseason opener behind an abysmal offensive line, rushing 3 times for -1 yard, becoming a meme in the process. Now, he’s set to make his Allegiant Stadium debut.
Below, we’ll break down Saturday’s 49ers vs. Raiders predictions for the preseason clash, and give you the best NFL DFS picks for PrizePicks for Saturday, August 16, including player projections.
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49ers vs. Raiders Predictions & NFL DFS Picks
Here are three of the top 49ers vs. Raiders predictions and NFL DFS picks for PrizePicks. Use this NFL preseason DFS analysis to help you build a Lineup on PrizePicks for Saturday, August 16. Click each pick to read more.
- Raiders RB Ashton Jeanty – 23.5 Rush Yards
- Raiders WR Phillip Dorsett – 17.5 Receiving Yards
- 49ers WR Robbie Chosen – 17.5 Receiving Yards
Raiders RB Ashton Jeanty — 23.5 Rushing Yards
- Raiders RB Ashton Jeanty finished his first NFL game with negative yardage, 3 carries for -1 yard.
- The 49ers allowed 153 rushing yards against the Broncos last week.
- Five of Denver’s seven RBs finished with 20+ yards against San Francisco.
- Last season at college, Jeanty was never held to under 100 yards in a game.
Raiders WR Phillip Dorsett — 17.5 Receiving Yards
- Raiders WR Phillip Dorsett was targeted a team-high 4 times last week.
- Dorsett hauled in 3 receptions for 36 yards.
- The 2015 fist round pick has not had 36+ yards in a game since December 24, 2022.
- San Francisco allowed 215 passing yards last week.
- Five Broncos receivers recorded 18+ yards against the 49ers defense in preseason Week 1.
49ers WR Robbie Chosen — 17.5 Receiving Yards
- 49ers WR Robbie Chosen was held to 1 reception for 1 yard against the Broncos.
- He played just 12 snaps — fourth on the team.
- The Temple graduate had just 5 yards last season after putting up 126 in 2023.
- San Francisco’s newest weapon spent his last two years in Miami.
- Las Vegas held Seattle to a 56.25% completion rate for only 198 yards last week.
- Chosen is entering his 10th year in the league, giving the 49ers little reason to give him extended run, as he'll come into the season as the team's WR4.
Play Preseason NFL DFS on PrizePicks
There’s exciting action on Saturday's NFL preseason slate, highlighted by the Raiders hosting the 49ers on NFL Network at 4 p.m. ET. With 11 NFL games on tap on Saturday, now is time to build your NFL Lineup on PrizePicks.
Just pick More or Less at least two NFL player stat projections to build your Lineup on PrizePicks — the more players you pick, the more you can win. Use the players above to build your Lineups around, or use a 6-Pick Lineup to reach up to 2000x payouts.
Check out the Playbook for more NFL DFS picks and analysis all the way through the 2025 NFL season.
