The Seahawks (14-3) host the 49ers (12-5) in a Divisional Round matchup that pits two NFC West foes against each other. Saturday’s game kicks off at 8:00 p.m. ET on FOX.
Seattle captured the top seed in the NFC playoff picture following a 13-3 win against San Francisco in Week 18, earning a first-round bye in the process. Meanwhile, the 49ers were forced to travel to Philadelphia to face off against the Eagles and managed to come away with a hard-fought 23-19 victory on Wild Card Weekend.
Below, we will use PrizePicks Team Picks data to make a 49ers vs. Seahawks spread prediction for the NFL playoff contest and point out some key trends to consider in the Divisional Round.
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49ers vs. Seahawks Spread, Over/Under
The Seahawks enter their Divisional Round showdown as 6.5-point home favorites, returning a 1.29x payout on PrizePicks Team Picks if they win outright.
The 49ers are road underdogs with a 3.33x payout if they win, via PrizePicks Team Picks.
- Spread: Seattle Seahawks -6.5
- Over/Under: 45.5
- Game Winner Payout: 49ers 3.33x | Seahawks 1.29x
Team Picks data is live at the time of writing and is subject to change.
49ers vs. Seahawks Spread Prediction for Divisional Round
Here are some stats to keep in mind for the Divisional Round, as well as a 49ers vs. Seahawks spread prediction.
- The Seahawks are tied for the best cover rate (70.6%), owning a 12-5-0 record against the spread. The 49ers are 11-6-1 ATS, the third-best cover rate in the NFL. Seattle is 4-4 ATS at home, with the 49ers being 2-2 ATS as road underdogs.
- San Francisco has covered in six of its last nine meetings against Seattle.
- According to Jefe’s Handiwork, the 49ers rank fifth in passing EPA per play (0.177) compared to a Seahawks defense that sits fourth (-0.065) against the pass.
- During the regular season, Seattle allowed just 285.6 total yards per game, good for sixth. San Francisco ranked seventh on offense with an average of 351.4 yards.
- 49ers RB Christian McCaffrey has a 4.40 efficiency rating, per NFL Pro. That ranks fifth behind only Broncos RB RJ Harvey (4.85), Falcons RB Tyler Allgeier (4.71), Seahawks RB Kenneth Walker III (4.5), and Bucs RB Bucky Irving (4.3).
- The Seahawks allowed the third-fewest rushing yards per game (91.9) during the regular season. McCaffrey rushed for 92 yards in two games vs. Seattle this year.
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Make 49ers vs. Seahawks Divisional Round Picks on PrizePicks
When Seattle and San Francisco take the field Saturday, there are ample opportunities for football fans to maximize player projections and much more in this Divisional Round matchup.
You can make 49ers vs. Seahawks picks on PrizePicks and PrizePicks Team Picks and earn real money. Just pick players, predict More or Less on their projected stats, and cash in if you’re correct. With Team Picks, make predictions on winners, spreads, and over/unders, now available in 30 states.
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