Thunder vs. Spurs Prediction on Spread for Game 3 – 5/22/26

Game 3 of the Oklahoma City Thunder vs. San Antonio Spurs in the Western Conference Finals is set to tip off at 8:30 p.m. ET on Friday, May 22, with the Spurs entering as 1.5-point favorites on the spread, via PrizePicks.

After splitting the first two games of the Western Conference Finals, the series shifts to San Antonio, where the Spurs won both matchups against the Thunder during the regular season. 

How important is Game 3? When tied 1-1 in a best-of-seven series, the Game 3 winner has gone on to win the series 72.3% of the time.

Below, we’ll break down our Thunder vs. Spurs prediction and picks for Friday’s NBA game, including the spread for PrizePicks.

Make your Thunder vs. Spurs picks on PrizePicks for Game 3 of the Western Conference Finals.

{{nba_offer_banner="/style-system/ui-components-playbook"}}

Thunder vs. Spurs Prediction, Spread, Over/Under for Game 3 – Friday, May 22

Injuries continue to be a story in the Thunder-Spurs series, as Oklahoma City G Jalen Williams (hamstring) and San Antonio G Dylan Harper (leg) both left Game 2 with injuries. Without PG De’Aaron Fox, the Spurs assist numbers declined by 12% in Game 2.

The NBA injury report currently lists Williams, Harper, and Fox as questionable for Friday night.

Spurs C Victor Wembanyama followed up his 41-point, 24-rebound performance in Game 1 with 21 points and 17 rebounds in Game 2. He is shooting 53.7% from the field through two games of this series. After attempting a playoff-career high 25 shots in Game 1, the Thunder held the Spurs star to 16 field goal attempts in Game 2. 

One game removed from 7-of-23 shooting (30.4%), two-time MVP Shai Gilgeous-Alexander made 12-of-24 shots (50.0%) for a game-high 30 points in Game 2. He leads all playoff scorers with 28.7 points per game.

Overall, the Thunder shot much better in Game 2, hitting 47.9% of their shots after struggling with a 40.6% field goal percentage to open the WCF. 

Thunder vs. Spurs Spread, Over/Under – Friday, May 22

The Spurs enter Friday’s game as 1.5-point favorites against the Thunder, returning a 1.75x payout if they win outright, via PrizePicks Team Picks.

Here are the full payouts for Thunder vs. Spurs on PrizePicks

• Spread: San Antonio Spurs -1.5 (1.81x payout)
• Over/Under: 218.5 (1.88x payout on Over)
• Game Winner Payout: Thunder 2x | Spurs 1.75x

Play the Thunder vs. Spurs spread or over/under on PrizePicks Team Picks to earn real money — available in 35 states!

Team Picks data is live at the time of writing and is subject to change.

Oklahoma City Thunder vs. San Antonio Spurs Timeline

Here is the full Thunder vs. Spurs timeline, including the playoff series game-by-game and recent matchup history.

All-Time: Spurs, 107-91

Regular Season: Spurs, 4-1

Postseason: Tied, 1-1

Thunder vs. Spurs Western Conference Finals Timeline, Schedule

• Game 1: Spurs, 122-115
• Game 2: Thunder, 122-113
• Game 3: Friday, May 22, 8:30 p.m. in San Antonio
• Game 4: Sunday, May 24, 8:00 p.m. in San Antonio
• Game 5: Tuesday, May 26, 8:30 p.m. in Oklahoma City
• Games 6-7 if necessary

Thunder vs. Spurs Prediction on Spread for Game 3 – 5/22/26

Here are the key stats and trends behind our Thunder vs. Spurs prediction on the spread for Friday, May 22

Lock in your Thunder vs. Spurs prediction on PrizePicks before Game 3 tips off.

• The Spurs are 55-39-2 against the spread this season. The 55 covers are the most of any team in the league. 
• After covering four of five games vs. the Trail Blazers in the first round and four of six games vs. the Timberwolves in the conference semifinals, San Antonio has covered in one of two games vs. the Thunder.
• The Spurs were an underdog in the first two games in Oklahoma City, breaking their streak of being favored in the first 11 playoff games. As a favorite, the Spurs are 41-32-2 ATS. The 41 covers are the third-most behind the Thunder and Knicks. 
• The Spurs have gotten it done on both sides of the ball. The offense is ranked third in the postseason in PPG, field goal percentage, offensive rating, and eFG%. On the defensive side, the Spurs lead all teams with a 103.9 defensive rating while holding opponents to 41.1% from the field.
• The Thunder are 45-47 this season against the number. That includes a 6-4 ATS record in the postseason.
• Friday night marks only the fifth time the Thunder have been underdogs this season. The defending champs are 2-2 ATS in the underdog role, but SGA did not play in any of the games. 
• The Thunder had the best defensive rating during the regular season (106.5) but are only sixth among postseason teams through 10 games. On the offensive side, the Thunder have the best offensive rating (123.4), the most PPG (120.7), and the second-highest field goal percentage (49.5%).

{{nba_offer_banner="/style-system/ui-components-playbook"}}

Make Thunder vs. Spurs Picks on PrizePicks

Will the Spurs remain unbeaten at home vs. the Thunder this season? Or will the defending champs grab a key road win and a 2-1 series lead?

Don’t wait until lock — make your Thunder vs. Spurs vs. picks on PrizePicks now and earn real money if you’re right.

With Team Picks, you can make predictions on game winners, spreads, and over/unders, now available in 35 states.

Stay locked in on Playbook for daily NBA predictions, picks, and news every day all the way through the 2026 NBA Finals.