The NBA is back in full force following Tuesday night’s action with a 12-game slate for Wednesday night. Out West, one of the more intriguing matchups takes place in Los Angeles.
Tipping off at 10:30 p.m. ET, the Nuggets and Clippers will square off from the Intuit Dome. In a regular-season rematch of April and May’s first-round playoff series, the conference foes will go head-to-head to see who gets bragging rights early on.
Below, we’ll break down a Nuggets vs. Clippers prediction and picks to consider for Wednesday night’s game. Use PrizePicks NBA to make player picks and win money if you’re right.
Nuggets vs. Clippers Prediction, Preview for Wednesday, 11/12
During the regular season, these two sides have played 197 times. The Nuggets own a commanding 110-87 series advantage, although the franchises split their four meetings in 2023 and 2024. In this past season’s Western Conference playoff stretch, Denver won in seven games.
Another advantage the Nuggets have entering Wednesday is health. They don’t have any noteworthy injuries on their roster, whereas the Clippers are slated to be without both G Bradley Beal (hip) and F Kawhi Leonard (ankle). Beal recently underwent evaluations on the hip.
Denver Nuggets Preview vs. Clippers
Despite the late-year firing of now-former head coach Mike Malone, the Nuggets turned their 50-32 record into a competitive Western Conference Semifinals fight with the eventual champion Thunder.
This year, Denver is proving their late surge was no fluke. They’re off to an 8-2 start, their best 10-game beginning to a season since the 2023 campaign.
Offensively, head coach David Adelman pushes an efficient attack that ranks second in two-point scoring, second in free throw percentage and third in points in the paint per game.
The Nuggets’ defense is no slouch, though, ranking inside the top five in fastbreak scoring and holding opponents to an ugly 30.5% mark from deep.
Los Angeles Clippers Preview vs. Nuggets
In a jam-packed Western Conference, last season’s Clippers also finished with 50 victories. Unfortunately, they ran into a hot Denver team and couldn’t get out of the aforementioned opening round of the playoffs.
Head coach Tyronn Lue's 2025 L.A. bunch is 3-7. They also started the 2023 season in similar fashion.
The Clippers are dead last in field goal attempts per game at 82.1, which could stem from them playing with the slowest pace in the sport.
Unlike in years prior, defense isn’t saving Los Angeles. It sits sixth in paint scoring allowed but allows more threes than anyone and is 25th in opposing assist-to-turnover ratio.
Nuggets vs. Clippers NBA Picks, Stats for PrizePicks Today
Here are three top Nuggets vs. Clippers picks to target on Wednesday. Key PrizePicks player projections are headlined by C Nikola Jokic and PGs Jamal Murray and James Harden.
Nuggets C Nikola Jokic vs. Clippers Projection: 1.5 3PT Made
- Jokic is taking 4.5 3-pointers per 36 minutes this year, down barely a hair from his 4.6 mark a season ago.
- The multi-time MVP went 11-for-21 (52.4%) on treys in just three regular-season outings against L.A. in 2024. In the first-round postseason slate, he made 45.2% of his tries.
- Per FantasyPros, the Clippers allow the 12th-most 3-point makes to the C position.
- Jokic’s 3-point rate of 25% is a career-high and ranks in the 74th percentile, per NBARAPM.
Nuggets PG Jamal Murray vs. Clippers Projection: 5.5 Asts
- Murray has averaged between 5.9 and 6.2 assists in each of his last four seasons.
- The 28-year-old managed at least 6 assists in four of his last six contests and three of his last four overall.
- Murray’s 16.5 potential assists per 100 possessions puts him in the 98th percentile, according to databallr.
- No team affords a higher per-game assist average to PGs than Los Angeles at 10.37.
Clippers PG James Harden vs. Nuggets Projection: 39.5 Pts+Rebs+Asts
- Harden averages 37.9 combined points, rebounds, and assists (PRA) in nine games. In his last five outings, that figure is 41.2.
- The Beard’s on-ball rate (42.2%) and potential assists per 100 (21.1) are both 100th-percentile marks, per databallr. His 25.4 true shot attempts per 100 put him in the 95th percentile.
- Harden averaged 5.43 rebounds per game in Los Angeles’ first-round playoff bout with Denver earlier this calendar year.
- With Beal and Leonard out, Harden may have significantly increased opportunities to command the Clippers’ offense.
Make NBA Picks on PrizePicks
Nuggets vs. Clippers isn’t the only avenue basketball fans have to make NBA picks. With PrizePicks, you can win real-money rewards for your predictions if you’re right.
Just choose players, predict More or Less on their projected stats, and follow the hoops action to see if your picks hit.
Stick around with the Playbook for continued NBA coverage and analysis all season.




