NASCAR Coca-Cola 600 Predictions, Starting Lineup at Charlotte Today

The NASCAR Coca-Cola 600 gets started on Sunday, May 24 at 6:00 p.m. ET at Charlotte Motor Speedway on Amazon Prime.

The atmosphere surrounding this Memorial Day weekend race is dampened due to the death of veteran driver Kyle Busch this week. Busch completed 762 NASCAR races over 24 years and fell victim to pneumonia and subsequent complications at 41 years old.

The race must go on and will start the engines in Charlotte for the 400-lap race, spanning 600 miles following last weekend’s All-Star festivities.

Below, we'll break down our NASCAR Coca-Cola 600 predictions and pick to win for Sunday’s race, including the starting lineup and top driver picks for PrizePicks.

Make your NASCAR picks for the Coca-Cola 600 on PrizePicks — and earn real money if you're right, available in North Carolina!

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NASCAR Coca-Cola 600 Winner, Top 10 Predictions for Charlotte – Sunday, May 24

Ross Chastain came out on top of last season’s Coca-Cola 600 after starting last. William Byron led for 283 laps, including winning each of the first two stages, but finished second and was denied his first Charlotte victory.

Five of the top seven drivers at last May’s event drove Chevrolets with A.J. Allmendinger, Chase Elliott, and Michael McDowell finishing behind Chastain and Byron.

Christopher Bell, Ryan Blaney, Denny Hamlin, and Kyle Larson have all won at this track since 2021. Hamlin and Larson each captured the pole in their victories, while the last five winners started sixth or higher.

Seven different drivers have won the past seven races, capped off by Hamlin’s victory at Dover in the All-Star event last Sunday.

The favorite to win the Coca-Cola 600 is Denny Hamlin entering Sunday's race, according to PrizePicks Team Picks.

Hamlin currently returns a 5x payout ($100 pays out $500) if he wins while several other drivers, including Reddick, are right behind him at a 5.55x payout to win at Charlotte, according to PrizePicks.

Payout multipliers listed (like 2x) indicate real-money earnings if your NASCAR predictions are correct; for example, 2x on a $100 entry pays $200 if correct — available in 35 states, including North Carolina. “Yes” payouts represent a specific outcome occurring, whereas "No" payouts indicate the opposite.

NASCAR Coca-Cola 600 Winner Payouts on PrizePicks

Here are the payouts for drivers to win the NASCAR Coca-Cola 600 from Charlotte Motor Speedway on PrizePicks. Make your Coca-Cola 600 pick on 'Yes' or 'No' for a driver to win.

• Denny Hamlin – Yes 5x | No 1.14x
• Tyler Reddick – Yes 5.55x | No 1.12x
• Kyle Larson – 6.66x | No 1.08x
• Christopher Bell – Yes 8.33x | No 1.04x
• William Byron – Yes 8.33x | No 1.02x
• Chase Elliott – Yes 9.09x | No 1.04x
• Chase Briscoe – Yes 10x | No 1.03x
• Ty Gibbs – Yes 11.11x | No 1.03x
• Carson Hocevar – Yes 11.11x | No 1.03x
• Ryan Blaney – Yes 11.11x | No 1.02x

NASCAR Starting Lineup for Coca-Cola 600: Reddick Earns Pole Position

The NASCAR Coca-Cola 600 qualifying took place on Saturday afternoon at Charlotte Motor Speedway. 

Reddick picked up his sixth pole victory of the season and finished in the winner’s circle four times (Atlanta, COTA, Darlington, and Kansas).

Here is the full NASCAR Coca-Cola 600 starting lineup at Charlotte Motor Speedway for Sunday.

Row 1: Tyler Reddick / Ty Gibbs

Row 2: Shane van Gisbergen / Michael McDowell

Row 3: Chase Briscoe / Ryan Blaney

Row 4: Chris Buescher / Austin Cindric

Row 5: Austin Dillon / AJ Allmendinger

Row 6: Denny Hamlin / Ryan Preece

Row 7: Austin Hill / Daniel Suarez

Row 8: John Hunter Nemechek / Chase Elliott

Row 9: Christopher Bell / Kyle Larson

Row 10: Zane Smith / Todd Gilliand

Row 11: Erik Jones / Cole Custer

Row 12: Carson Hocevar / Bubba Wallace

Row 13: Connor Zilisch / Brad Keselowski

Row 14: Ross Chastain / Noah Gragson

Row 15: Alex Bowman / Riley Herbst

Row 16: William Byron / Ricky Stenhouse, Jr.

Row 17: Joey Logano / Josh Berry

Row 18: Ty Dillon / Timmy Hill

Row 19: Katherine Legge / Cody Ware

Row 20: Corey Heim

NASCAR Coca-Cola 600 Predictions, Driver Picks for Charlotte Motor Speedway

Here are three of the top Coca-Cola 600 picks to target in the NASCAR race from Charlotte Motor Speedway on Sunday. Top PrizePicks NASCAR picks are headlined by three drivers: William Byron, Ty Gibbs, and Ryan Blaney.

William Byron – 7.5 Finishing Position

William Byron to Finish Top 10 in Coca-Cola 600: Yes 1.38x | No 1.36x

• Byron has been the most consistent Charlotte driver the last five events, placing higher than fourth on four occasions.
• He seeks his first Charlotte victory despite capturing the opening stage and leading for 423 laps in the last three years.
• Byron completed his 300th career NASCAR race two weeks ago at Watkins Glen but posted his worst finish of the season at 36th.
• The driver of the #24 Chevy has seen success in three events at intermediate and large oval tracks in 2026, placing higher than eighth each time.

Add William Byron to your PrizePicks NASCAR Picks for the Coca-Cola 600.

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Ty Gibbs – 10.5 Finishing Position

Ty Gibbs to Finish Top 10 in Coca-Cola 600: Yes 1.29x | No 1.29x

• In three career Charlotte events, Gibbs placed in the top 10 once, finishing sixth in 2024.
• He won the pole in the 2024 event and will start second on Sunday. It marks his best starting position of this season.
• Gibbs has been the poster child of feast or famine in 2026. He owns eight top-10 finishes but has also closed 34th or worse three times.
• In 2025, Gibbs finished in the top 10 once in 11 races at intermediate and large oval tracks. This season, he owns a pair of top-10 finishes and crashed out at Texas earlier this month.

Add Ty Gibbs to your PrizePicks NASCAR Picks for the Coca-Cola 600.

Ryan Blaney – 7.5 Finishing Position

Ryan Blaney to Finish Top 10 in Coca-Cola 600: Yes 1.42x | No 1.35x

• Since winning at Charlotte in 2023, Blaney crashed out the last two years at this track, placing 38th and 39th. 
• In four of the last five Charlotte events, Blaney has finished 13th or lower.
• Blaney posted a strong five-race stretch placing higher than 6th four times from early March through mid-April.
• However, he has hit the skids lately with four consecutive finishes of 10th or lower.

Add Ryan Blaney to your PrizePicks NASCAR Picks for the Coca-Cola 600.

Make NASCAR Coca-Cola 600 Predictions on PrizePicks

The annual Memorial Day event in Charlotte may experience plenty of emotion following Busch’s passing this week, but the excitement could be high once the flags drop for 600 miles to see if Reddick can grab his sixth victory of the season.

Don’t wait until lock — make your NASCAR Coca-Cola 600 predictions on PrizePicks now and earn real money if you’re right.

There are unique picks on the NASCAR board for every race, including driver points and starting position; just pick at least two drivers to build your Lineup on PrizePicks. Or, make your picks on race winners on Team Picks, now available in 35 states, including North Carolina!

Stay locked in to Playbook throughout the season for more NASCAR picks, predictions, and news every day.