The lights will be bright in Orchard Park, New York, tonight, as the Ravens travel to New York to take on the Buffalo Bills on Week 1 Sunday Night Football.
Below, we'll breakdown our Ravens vs. Bills Sunday Night Football prediction and picks in the most anticipated matchups of Week 1. Two AFC heavyweights collide in primetime, both with playoff aspirations, and both led by MVPs; this early-season clash could set the tone for the 2025 season for both teams.
Will the Ravens’ reloaded ground game wear down Buffalo’s front seven, or can Allen light up the scoreboard and bring the Bills Mafia to its feet under the primetime spotlight?
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Ravens vs. Bills Prediction, Preview for Sunday Night Football
The Baltimore Ravens come in retooled and ready to finally get QB Lamar Jackson to the finish line — a Super Bowl, but their path starts with a hostile road test in Buffalo.
On the other side, Josh Allen and the Bills are determined to prove their Super Bowl window hasn’t closed yet, especially after last year’s rocky finish left a sour taste in Western New York.
The rivalry between QB Josh Allen and QB Lamar Jackson — two NFL MVP winners — is unmatched. These two are even with three wins apiece in their six matchups versus each other, and they've given us some great games.
Jackson has the edge in the regular season (3-of-4), but Allen owns a 2-0 advantage in the postseason.
This Ravens vs. Bills rematch of the 2024 Divisional Round game is a great way to kick off the season with a primetime game between two teams looking to finally get over the Super Bowl hump.
Baltimore Ravens Preview
Baltimore has high expectations coming into 2025. The Ravens were bounced from the playoffs by Buffalo again last season after TE Mark Andrews dropped the game-tying two-point conversion.
The Ravens made moves to bolster both sides of the ball. With the additions of WR DeAndre Hopkins and CB Jaire Alexander, the Ravens put themselves in a position to contend once again for not only the AFC Championship, but also the Super Bowl.
Buffalo Bills Preview
Buffalo yet again comes off a disappointing season after losing to the Kansas City Chiefs in the AFC Championship. Allen played nearly flawless football, leading Buffalo to a game-tying TD.
However, QB Patrick Mahomes used his tricks up his sleeve to get into field goal range to send the Bills packing. Buffalo is hoping this is finally the year, and they made a key addition on the defensive side of the ball with the signing of DE Joey Bosa.
They hope that Bosa’s pass-rushing abilities will help the back-end of the defense, which struggled in key moments last season.
Ravens vs. Bills Picks for NFL DFS & PrizePicks
Here are three Ravens vs. Bills player picks for Sunday Night Football in Week 1 for PrizePicks real money NFL game, including Josh Allen, Lamar Jackson, and RB Derrick Henry.
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Bills QB Josh Allen Projection vs. Ravens: 0.5 Rush+Rec TDs
Bills QB Josh Allen is an integral part of this offense. Not only through the air but also on the ground. Allen finished the 2024 season with 12 rushing TDs, which was just two shy of Jalen Hurts’ league-leading 14 TDs
When the Bills enter the red zone, the threat of Allen running it in the end zone keeps the defense on their heels. Much like he did against Baltimore in 2024. In that game, he rushed in two TDs with 20 yards on 10 carries
Allen scored a rushing TD in 9 of 20 games last year, including the playoffs.
If Buffalo wants to come away with a big statement win over Baltimore, Allen will need to do everything to get the job done.
Ravens QB Lamar Jackson Projection vs. Bills: 46.5 Rush Yards
Much like Allen, Ravens QB Lamar Jackson is the motor of this offense. He’s versatile and can make incredible throws, but he is sometimes most effective as a runner.
He may not have the same TD upside of Allen, but his ability to extend plays and create something out of nothing makes him dangerous. Against Buffalo in 2024, Jackson had 93 rushing yards between two games.
Jackson averaged 54 yards rushing per game in 2024.
It will be up to Jackson to make plays not only with his arm, but with his feet to come away with another regular-season win against Buffalo on Sunday night.
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Ravens RB Derrick Henry Projection vs. Bills: 83.5 Rush Yards
Baltimore RB Derrick Henry was a massive addition to this Ravens offense in 2024. He finished the 2024 season with 1,921 rushing yards and 16 rushing TDs. Henry was second in the league in rushing yards only behind Eagles RB Saquon Barkley, and tied for the NFL lead in rushing TDs.
Against Buffalo, he was just as dominant in two outings. Henry ran all over Buffalo twice in 2024, rushing for 283 yards and 2 TDs. He should continue to get plenty of opportunities in 2025 to do the same — Henry had 20 or more carries in nine games last year.
The Bills' run defense is one of their main weaknesses, as they only ranked 12th best in run defense success rate in 2024, per rbsdm. They ranked 25th in run defense grade according to PFF.
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Will the Ravens get revenge for their 2024 playoff loss and remain dominant in the regular season against the Bills? Or will the Bills prove that it's their time and kick off the 2025 season with a statement win on Sunday Night Football?
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On PrizePicks, you're the GM — no draft, no roster headaches. Pick two to six players, choose any stat you want — from passing yards to touchdowns — then pick More or Less on the projection. Hit submit and see how your picks stack up. Try building your Sunday Night Football Lineup now on PrizePicks.
