For the third straight season, both Eagles WR A.J. Brown and Rams RB Kyren Williams have made the playoffs. They will be in action on Wild Card Weekend and will attempt to exploit favorable matchups to help their teams advance to the next round.
Below, we'll discuss Brown, Williams, and get into more of the top NFL Wild Card Weekend picks for PrizePicks, including some quick picks to keep in mind.
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Quick PrizePicks Picks for NFL Wild Card Weekend
Here are some quick PrizePicks picks for NFL Wild Card Weekend, including projections for pass yards, rush yards, and receiving yards.
Packers QB Jordan Love vs. Bears Projection: 223.5 Pass Yards
- In the one full game that Packers QB Jordan Love played against the Bears this season, he threw for 234 yards in a 28-21 win in Week 14.
- The Bears were tied for the fifth-most yards per pass attempt allowed (7.63) during the regular season.
Bills RB James Cook III vs. Jaguars Projection: 79.5 Rush Yards
- Bills RB James Cook III received at least 17 carries in a game 11 times during the regular season. Over those 11 games, he averaged 117.7 rush yards.
- On his way to setting a new career high with 1,621 rush yards this season, Cook posted at least 80 rushing yards in a game 11 times. That included nine games with at least 100 yards on the ground.
Bills WR Brandin Cooks vs. Jaguars Projection :42.5 Receiving Yards
- Bills WR Brandin Cooks was rested for a meaningless Week 18 matchup against the Jets. The week prior, he caught 4 of 5 targets for 101 yards in a 13-12 loss to the Eagles.
- The Bills are still searching for reliable pass-catchers behind WR Khalil Shakir, with WR Keon Coleman having been made inactive for two of their final three games. Coleman had a total of 6 receptions over the last eight weeks.
NFL Wild Card Weekend Picks for PrizePicks
Here are the top picks for NFL Wild Card Weekend. Player projections via the PrizePicks real money NFL game.
Eagles WR A.J. Brown vs. 49ers Projection : 66.5 Receiving Yards
- Brown was targeted 54 times over his first eight games of the season. Across the last seven games, he had 67 passes thrown his way.
- With the Eagles looking towards their top wide receiver more often, the former second-round pick totaled at least 68 receiving yards in five of his last seven games. That included three games with at least 100 receiving yards.
- The 49ers gave up the ninth-most receptions to wide receivers during the regular season.
- San Francisco wasn’t just allowing a bunch of short catches. They permitted the fifth-most yards per target to wide receivers (8.36).
Rams RB Kyren Williams vs. Panthers Projection: 64.5 Rush Yards
- Williams ran for at least 70 yards in eight of 10 games following the Rams’ bye in Week 8.
- The fourth-year back has proven to be difficult to bring down, averaging 3.1 yards after contact.
- The Panthers have allowed the ninth-most yards per carry to running backs (4.59).
- When Williams played Carolina in Week 13, he turned 13 carries into 72 yards in a 31-28 loss.
Panthers WR Tetairoa McMillan vs. Rams Projection: 52.5 Receiving Yards
- Panthers WR Tetairoa McMillan recorded at least 60 receiving yards in nine of his 17 games.
- The rookie had a 25.8% target share this season and accounted for 44.9% of the Panthers’ air yards.
- While he was only targeted 2 times against the Rams in Week 13, he turned one of them into a 43-yard TD reception.
- With teams often needing to throw a lot to keep up with the Rams’ high-powered offense, Los Angeles gave up the tenth-most receptions to wide receivers in the league.
Packers WR Christian Watson vs. Bears Projection: 55.5 Receiving Yards
- Watson has provided mixed stat lines in two meetings with the Bears. He had 4 receptions for 89 yards and 2 TDs against them in Week 14, but only caught 2 passes for 17 yards in Week 16 with Love departing early because of an injury.
- The 26-year-old had an average depth of target of 17.3 yards this season and was responsible for 23.8% of the Packers’ air yards.
- Per 4for4 Football, the Bears allowed the sixth-highest explosive pass percentage (13.6%) in the NFL.
- Chicago also permitted the second-most completions of at least 20 yards (61).
49ers QB Brock Purdy vs. Eagles Projection: 16.5 Rush Yards
- 49ers QB Brock Purdy ran for at least 21 yards in three of his last four games. In two of those matchups, he finished with at least 6 rush attempts.
- After averaging 4.9 yards per carry in 2024, the fourth-year signal caller averaged 4.5 yards per carry this season.
- The Eagles put a lot of pressure on opposing quarterbacks, registering the seventh-most quarterback hits.
- With quarterbacks often forced to scramble against them, the Eagles were tied for the fifth-most rushing attempts allowed to the position.
Chargers WR Keenan Allen vs. Patriots Projection: 3.5 Receptions
- Chargers WR Keenan Allen hauled in at least 4 passes in 13 of 17 games.
- The cagey veteran has a 22.4% target share during his second stint with the Chargers.
- Patriots star CB Christian Gonzalez could spend much of the game on Chargers top WR Ladd McConkey, which could force more targets towards Allen.
- Teams only completed 53.6% of their pass attempts to players that Gonzalez was covering during the regular season.
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Make NFL Wild Card Weekend Picks on PrizePicks
Brown and Williams will try to help lead their respective squads to wins during Wild Card Weekend. In addition to them possibly producing juicy stat lines, we could see excellent performances from players from McMillan, Watson, and Purdy, among others.
With plenty of positions and projection categories to consider, now is the time to build your NFL Lineup on PrizePicks. Just pick More or Less for at least two NFL player stat projections to build your Lineup on PrizePicks. Check out the Playbook for more NFL picks and analysis throughout the playoffs.




