The Lions and Bears cap off the 2025 regular season with a Week 18 matchup that will decide the Bears' playoff seed.
While the Lions are eliminated from postseason contention, the Bears, depending on Saturday night’s Seahawks-49ers result, could be the NFC's two or three seed.
The Lions and Bears Week 18 rumble kicks off Sunday at 4:25 p.m. ET on Fox.
Below, we'll break down our Lions and Bears prediction and picks for Week 18, including the top player picks on PrizePicks real money NFL game, including Lions QB Jared Goff and Bears QB Caleb Williams and WR DJ Moore.
Lions vs. Bears Over/Under Picks, Spread
The Lions and Bears meet for the second of their annual two meetings after the Lions took the first meeting, 52-21 in Detroit in Week 2. Since that loss, the Bears have won 11 of 14 games and won the NFC North.
Lions vs. Bears Over/Under, Spread
The Bears enter the Week 18 contest as 2.5-point favorites, returning a 1.58x payout on PrizePicks Team Picks if they win.
The Lions are underdogs with a 2.22x payout if they win, via PrizePicks Team Picks.
- Spread: Chicago Bears -2.5
- Total: 50.5
- Game Winner Payout: Lions 2.22x | Bears 1.58x
Lions vs. Bears Prediction on Spread
The Bears roll into this NFL North tussle as a 2.5-point favorite over the Lions, the first time Chicago has been the favorite in this matchup since 2023.
- The Lions are 7-9 against the spread this season, their worst season against the number since Dan Campbell took over as head coach in 2021.
- Since Campbell arrived, the Lions are 24 games over .500 against the spread, four games better than any other team.
- Detroit is 1-4 (20%) as an underdog this season, the worst cover percentage of any team as an underdog in 2025.
- The lone cover as an underdog this season for Detroit was in Week 3, a 38-30 outright win in Baltimore as 4.5 point 'dogs.
- The Lions enter Week 18 third in the league in scoring offense at 28.9 points per game. They are sixth in the league in total offense and fifth in passing offense.
- On the defensive side, Detroit is tied for 22nd in scoring defense at 24.8 PPG.
- The Bears are 10-6 against the spread this season, their best ATS record since 2018 (12-5).
- It’s a complete turnaround for the Bears, as they had the third worst cover percentage (41.1%) from 2019-24.
- Chicago is 5-1 ATS as a favorite this season, second best to Jacksonville (6-1).
- The Bears sit tenth in the NFL in scoring offense at 26.6 PPG and third in total offense at 375.8 yards per game. The last time Chicago finished top-five in total yards was the 1977 season.
- On the defensive side, the Bears are tied 22nd in scoring defense (24.8 PPG) and 28th in total defense.
Lions vs. Bears Picks for PrizePicks
Here are three Lions vs. Bears player picks for Week 18 for PrizePicks real money NFL game, including Lions QB Jared Goff and Bears QB Caleb Williams and WR DJ Moore.
Pick More or Less on these projections on PrizePicks — plus thousands more — to win real money this NFL season. Or, make your picks on winners, spreads, and over/unders on Team Picks, now available in 30 states.
Lions RB Jared Goff Projection vs. Bears: 253.5 Pass Yards
- Lions QB Jared Goff has reached his passing projection in nine of 16 games.
- He did not hit his passing projection last week vs. the Vikings, ending a streak of five straight games of exceeding it.
- Goff has passed for 255+ yards in eight of the last nine games, with the 197-yard effort last week being the only one without more than 255 passing yards.
- The Lions signal caller is second in the NFL in TDs with 33 and third in passer rating at 107.0.
Bears WR DJ Moore Projection vs. Lions: 34.5 Receiving Yards
- Bears WR DJ Moore has reached his receiving yards projection in half (eight) of his games (16) this season.
- The listed projected receiving mark of 34.5 yards is the second-lowest projection of the season for the former Panther.
- Moore has been inconsistent this season, with nine games of 40+ receiving yards and six with fewer than 25.
- Three of Moore’s 6 receiving TDs have come over the last three games.
Bears QB Caleb Williams Projection vs. Lions: 237.5 Pass Yards
- Bears QB Caleb Williams has reached his passing projection in half of his 16 games (16).
- The 237.5 passing projection is tied for the highest projection of the season for Williams (Week 9 against Bengals was 238.5) and also tied for the second-highest of his two-year career.
- Williams has passed for 240+ yards in three straight games, with 6 TDs and 0 INTs.
- The Bears QB needs 270 passing yards to reach 4,000 passing yards, something no Bears QB has ever done.
Make Lions vs. Bears Predictions on PrizePicks
Can the Lions sweep the Bears and end their season on a high note? Or will the NFC North Champion Bears win their 12th game for the first time since 2018?
As the NFL season enters its 18th week, there's no better place to get real money action with your NFL predictions than on PrizePicks.
There is a wide variety of player stat projections on the NFL board, so you can make predictions on whatever you'd like — from yards to field goals. Just pick your players, predict More or Less on their stats, and cash in on your predictions if you're right. Or make your picks on winners, spreads, and over/unders on Team Picks, now available in 30 states.
It's the simplest way to get real-money action on NFL action.
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